The Baltimore Orioles (67-61) and the Cleveland Guardians (68-59) play the middle contest of a 3-game set at Progressive Field Wednesday. First pitch is scheduled for 6:10 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Orioles at Guardians odds with MLB picks and predictions.
Season series: Guardians lead 3-1
The Orioles have dropped 2 games in a row, and the offense has hit the collective skids lately. Baltimore has amassed just 2 total runs in the past 2 losses, and 14 combined runs — or 2.3 runs per game — across its last 6 showings.
The Guardians are clinging to first place in the AL Central with a 1.5 game buffer ahead of the Minnesota Twins after Cleveland’s 5-1 win over Baltimore in the series opener Tuesday.
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Orioles at Guardians projected starters
RHP Jordan Lyles vs. RHP Triston McKenzie
Lyles (9-9, 4.45 ERA) makes his 27th start. He has a 1.46 WHIP, 2.8 BB/9 and 7.5 K/9 through 145 2/3 IP.
- Has a dismal 5.85 ERA across 75 1/3 IP over 14 road starts vs. a 2.94 ERA in 70 1/3 IP across 12 home outings
- Is 2-1 with a 3.95 ERA over 27 1/3 IP through 5 August starts
- Looking for back-to-back winning months for the first time Aug.-Sept. 2019 when he was a member of the Milwaukee Brewers
McKenzie (9-10, 3.17 ERA) makes his 24th start and 25th appearance. He has a 0.96 WHIP, 2.3 BB/9 and 8.7 K/9 through 147 2/3 IP.
- Is 5-2 with a 2.78 ERA and .185 opponent batting average across 58 1/3 IP over 9 home starts
- Allowed 5 ER with 3 HR on 3 H and 3 BB with 4 K across 7 IP in a loss at Baltimore June 4
Orioles at Guardians odds and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6 a.m. ET.
- Money line (ML): Orioles +140 (bet $100 to win $140) | Guardians -175 (bet $175 to win $100)
- Run line (RL)/Against the spread (ATS): Orioles +1.5 (-150) | Guardians -1.5 (+122)
- Over/Under (O/U): 7.5 (O: -130 | U: +105)
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Orioles at Guardians picks and predictions
Prediction
Guardians 4, Orioles 2
Money line
The GUARDIANS (-175) are rather heavy favorites, but they’re a good play behind McKenzie. He has been lights out at home, while Lyles has been very giving on the road. McKenzie should also have revenge on his mind after serving up 3 HR to the O’s in his first meeting with them back in early June.
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Run line/Against the spread
The GUARDIANS -1.5 (+122) are worth a roll of the dice at plus money but don’t expect this one to be a blowout. The Orioles have had trouble scoring lately, but Cleveland has dropped 3 of its last 5 games to allow Minnesota to reel it in somewhat for the division crown.
Over/Under
The UNDER 7.5 (+105) is a decent value at plus money.
The O’s have had a power outage lately, averaging just more than 2 runs per game across the previous 6 outings. The Guardians haven’t exactly set the world afire either, scoring just 12 total runs across their previous 5 contests — just 2.4 runs per game.
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