Houston Astros at Boston Red Sox odds, picks and predictions

Analyzing Monday’s Houston Astros at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Houston Astros (74-58) and Boston Red Sox (69-62) start a 3-game series at Fenway Park Monday. First pitch is slated for 7:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Astros vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 2-2

The Astros started their 6-game road trip with a series win in Detroit, outscoring the Tigers 27-10 over their 3 games. Houston heads to Boston after splitting a 4-game series with the Red Sox less than a week ago at Minute Maid Park. They are 39-27 on the road this season.

The Red Sox started their 6-game homestand with a series loss to the Dodgers. Boston scores the 4th-most runs per game at home in the MLB at over 5 per game. They are 36-30 at Fenway Park this season.

Astros at Red Sox projected starters

RHP Cristian Javier vs. LHP Chris Sale

Javier (9-2, 4.52 ERA) will make his 25th start. He has a 1.26 WHIP, 3.2 BB/9 and 8.1 K/9 in 127 1/3 innings.

  • Last start: Win, 5 IP, 3 ER, 7 H, 3 BB, 3 K in 9-4 home win against the Red Sox Monday
  • 2023 road stats: 4-1, 5.33 ERA (74 1/3 IP, 44 ER), .231 OBA in 14 starts
  • Has not lost a start since July 22

Sale (5-3, 4.68 ERA) will make his 15th start. He has a 1.14 WHIP, 2.3 BB/9 and 11.1 K/9 in 73 innings.

  • Last start: No-decision, 5 IP, 4 ER, 6 H, 1 BB, 9 K in 7-5 road win at the Houston Astros Wednesday
  • 2023 home stats: 1-0, 3.69 ERA (31 2/3 IP, 13 ER), .190 OBA in 6 starts
  • Has not won a start since May 26

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Astros at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:04 a.m. ET.

  • Moneyline (ML): Astros +105 (bet $100 to win $105) | Red Sox -125 (bet $125 to win $145)
  • Run line (RL)/Against the spread (ATS): Astros +1.5 (-190) | Red Sox -1.5 (+155)
  • Over/Under (O/U): 9.5 (O: -115 | U: -105)

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Astros at Red Sox picks and predictions

Prediction

Astros 6, Red Sox 5

Moneyline

BET ASTROS (+105).

There is a reason that the odds are so tight for this game, it’s hard to handicap but I’m going to bet the talent of the Astros to get the victory.

Sale has not beaten the Astros since July 2, 2016.

Run line/Against the spread

PASS.

I don’t like the run line either way in this game. I’m going to look toward the run total.

Over/Under

BET OVER 9.5 (-115).

These teams played a 4-game series just a week ago and all 4 games in that series went over this total. The Astros score over 5 runs per game on the road and the Red Sox score over 5 runs per game at home.

These 2 starters also allowed at least 3 ER in their last starts against each other’s teams.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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