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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Sunday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (44-45) and San Diego Padres (49-44) close out a 3-game series Sunday. First pitch from Petco Park is at 4:10 p.m. ET (Roku). Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 5-4

The Diamondbacks, after losing Friday’s opener on a walk-off homer, scored 3 runs in the 10th inning to win 7-5 Saturday and even the series. They are 5-2 in their last 7 games.

Saturday’s loss for the Padres was just their 4th in their last 16 games overall and their 2nd in their last 11 at home.

Diamondbacks at Padres projected starters

RHP Ryne Nelson vs. RHP Dylan Cease

Nelson (5-6, 5.42 ERA) makes his 14th start and 16th appearance. He has a 1.56 WHIP, 2.3 BB/9 and 6.0 K/9 in 73 innings.

  • Last start: No-decision, 5 IP, 1 ER, 6 H, 1 BB, 3 K in 6-5 road loss to Los Angeles Dodgers Tuesday
  • 2024 vs. Padres: 1-1, 9.72 ERA (8 1/3 IP, 9 ER), 2.28 WHIP, 4.3 K/9 in 2 starts
  • Career vs. Padres: 2-3, 6.95 ERA (33 2/3 IP, 26 ER), 1.57 WHIP, 6.1 K/9 in 7 starts

Cease (7-7, 4.24 ERA) makes his 19th start. He has a 1.12 WHIP, 2.8 BB/9 and 11.5 K/9 in 102 innings.

  • Last start: Loss, 3 2/3 IP, 6 ER, 8 H, 2 BB, 5 K in 7-0 road loss to Texas Rangers Tuesday
  • Has allowed 4+ runs 6 times this season, 3 times in his last 4 outings
  • 2024 vs. Diamondbacks: 1-0, 1.35 ERA (6 2/3 IP, 1 ER), 3 H, 0 BB, 8 K in 1 start, a 7-1 road win May 3
  • Career vs. Diamondbacks: 1-0, 1.84 ERA (14 2/3 IP, 3 ER), 0.41 WHIP, 9.8 K/9 in 2 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Diamondbacks at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:36 a.m. ET.

  • Moneyline (ML): Diamondbacks +135 (bet $100 to win $135) | Padres -160 (bet $160 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-150) | Padres -1.5 (+125)
  • Over/Under (O/U): 8 (O: -120 | U: +100)

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Diamondbacks at Padres picks and predictions

Prediction

Padres 8, Diamondbacks 6

Moneyline

The Diamondbacks are 2 walk-off hits from a 7-game winning streak. They have scored 7 runs or more in 4 straight games.

But Nelson has struggled against the Padres (-160) this season and Cease’s 1 start against Arizona was a good one.

Arizona is 22-24 on the road this season and 17-25 against teams with winning records, so expect the Padres to bounce back and win the finale and the series, but there are plus odds on the run line to bet.

PASS.

Run line/Against the spread

All 5 of the Padres’ wins over the Diamondbacks have been by 2 or more runs. Nine of their last 10 wins have been by 2 or more runs. Nine of their 10 wins with Cease starting have been by at least 2 runs.

Twelve of Arizona’s last 13 losses have been by multiple runs.

BET PADRES -1.5 (+125).

Over/Under

Eight of the 9 games this season between Arizona and San Diego have had more than 8 total runs.

Three of Cease’s last 4 starts have had more than 8 total runs.

The Diamondbacks’ last 5 games, and 9 of their last 11, have had more than 8 total runs.

BET OVER 8 (-120).

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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Saturday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (43-45) and San Diego Padres (49-43) face off Saturday for the 2nd game of their 3-game series. First pitch from PETCO Park is at 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 5-3.

The Diamondbacks lost the opener Friday 10-8 on a walk-off home run by 3B Manny Machado after they scored 6 in the top of the 9th to take a 8-7 lead. The Over (8.5) cashed in. The D-Backs have still won 4 of 6.

The Padres’ win gave them 3 straight. They are 12-3 in their last 15 games after losing 5 in a row.

Diamondbacks at Padres projected starters

RHP Brandon Pfaadt vs. RHP Matt Waldron

Pfaadt (3-6, 4.28 ERA) makes his 18th start. He has a 1.18 WHIP, 2.3 BB/9 and 8.2 K/9 through 103 innings.

  • Last start: No-decision, 6 IP, 1 ER, 5 H, 2 BB, 8 K in 5-1 home win over Oakland A’s Sunday
  • 0-2 with 6.35 ERA in 2 starts vs. Padres this year

Waldron (5-7, 3.56 ERA) makes his 18th start. He has a 1.19 WHIP, 2.7 BB/9 and 8.4 K/9 through 93 2/3 innings.

  • Last start: Loss, 4 1/3 IP, 4 R (3 ER), 6 H, 1 BB, 3 K in 4-1 road loss to Boston Red Sox on Sunday
  • Got the win in a 13-1 victory June 8 over Arizona, allowing 1 run in 6 innings
  • 1-2 with 8.36 ERA in 3 career starts vs. Arizona

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Diamondbacks at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11 a.m. ET.

  • Moneyline (ML): Diamondbacks +100 (bet $100 to win $100) | Padres -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-225) | Padres -1.5 (+165)
  • Over/Under (O/U): 7.5 (O: +100 | U: -120)

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Diamondbacks at Padres picks and predictions

Prediction

Diamondbacks 7, Padres 6

Moneyline

The Diamondbacks are 2 walk-off hits from a 6-game winning streak. They scored 6 in the 9th inning to take a 1-run lead, only to have closer Paul Sewald give up 2 homers in the bottom of the inning. They have scored 29 runs in their last 3 games.

The Padres are 12-3 in their last 15 games and 10-1 in their last 11 home games.

Waldron picked up his 1st career win over Arizona last month, but he has struggled in 2 other career starts, while Pfaadt has struggled against the Padres this season.

The bats will be active.

BET DIAMONDBACKS (+100). 

Run line/Against the spread

Of the last 18 times the Diamondbacks have covered the spread, 17 have been outright wins.

Of the last 8 times that the Padres failed to cover the spread, 7 were outright losses.

And at -225 odds, you are far better taking the even-money odds for an Arizona outright win than the cover.

PASS. 

Over/Under

Six of the last 7 meetings this season have had double-digit runs.

The Diamondbacks have scored 5 or more runs in 5 straight games. Eight of their last 10 games have had more than 7 total runs.

BET OVER 7.5 (+100). 

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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Friday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (43-44) open a 3-game road series against the San Diego Padres (48-43) Friday. First pitch from Petco Park is at 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 4-3

The Diamondbacks are coming off a series win on the road over the Los Angeles Dodgers. They won the finale 9-3 Thursday behind 1B Christian Walker‘s 2 homers and a 4-run 9th inning to blow the game open. They have won 4 of their last 5 games.

The Padres are 11-3 since losing 5 straight games June 14-18. They went 4-2 on their 6-game road trip and won the final 2 games of a series against the Texas Rangers, beating them 3-1 Thursday.

Diamondbacks at Padres projected starters

RHP Slade Cecconi vs. RHP Randy Vasquez

Cecconi (2-6, 5.81 ERA) makes his 12th start and 13th appearance. The rookie has a 1.26 WHIP, 1.7 BB/9 and 7.5 K/9 in 57 1/3 innings.

  • Last start: No-decision, 4 IP, 3 ER, 5 H, 2 BB, 7 K in 9-4 home loss to Oakland A’s June 28
  • 2024 vs. Padres: 0-1, 9.35 ERA (8 2/3 IP, 9 ER), 1.73 WHIP, 7.3 K/9 in 2 starts
  • Career vs. Padres: 0-1, 7.84 ERA (10 1/3 IP, 9 ER), 1.55 WHIP, 7.0 K/9 in 3 appearances (2 starts)

Vasquez (2-4, 4.88 ERA) makes his 12th start. The rookie has a 1.67 WHIP, 2.3 BB/9 and 5.6 K/9 in 51 2/3 innings.

  • Last start: No-decision, 4 IP, 1 ER, 5 H, 1 BB, 1 K in 9-2 road win over Boston Red Sox June 28
  • Went 2-1 with 4.20 ERA in 6 June starts
  • 2024 vs. Diamondbacks: 0-0, 4.05 ERA (6 2/3 IP, 3 ER), 6 H, 0 BB, 3 K in 1 start, a 4-3 home loss June 6
  • Career vs. Diamondbacks: 0-0, 5.00 ERA (9 IP, 5 ER), 1.22 WHIP, 5.0 K/9 in 2 appearances (1 start)

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Diamondbacks at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:17 p.m. ET.

  • Moneyline (ML): Diamondbacks -115 (bet $115 to win $105) | Padres -105 (bet $105 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks -1.5 (+145) | Padres +1.5 (-175)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

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Diamondbacks at Padres picks and predictions

Prediction

Padres 6, Diamondbacks 4

Moneyline

The Diamondbacks have lost their last 2 series openers. They are 21-23 on the road this season.

The PADRES (-105) are 24-22 at home this season but are 9-1 in their last 10 games at Petco Park. They have won 3 of the last 4 starts for Vasquez.

The Diamondbacks are 1-3 in Cecconi’s last 4 outings.

BET PADRES (-105).

Run line/Against the spread

The last 10 times the Padres covered the spread, they won the game outright.

So at -175 odds for them to cover the +1.5, you’re better off going with the moneyline.

PASS.

Over/Under

Five of the 7 games between the teams this season have had double-digit runs, including 3 of the 4 in San Diego June 6-9.

Vasquez’s last 3 starts and 4 of his last 6 have had totals of 10 or more.

The Diamondbacks have scored 5 or more runs in 4 straight games and 21 runs in the last 2 games alone.

Nine of the Padres’ last 10 wins have had more than 8 total runs.

BET OVER 8.5 (-110).

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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Sunday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (30-35) and San Diego Padres (34-34) wrap up a 4-game series at Petco Park Sunday. First pitch is scheduled for 4:10 p.m. ET (ESPN+). Let’s analyze FanDuel Sportsbook’s lines around the Diamondbacks vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 4-2

The Diamondbacks won the series opener Thursday by a 4-3 score, but the Padres have been rude hosts the past 2 days. San Diego won 10-3 on Friday, and 13-1 on Saturday, easily cashing as the favorite while hitting the Over both days.

Despite the 2 blowout losses, Arizona is still a respectable 5-3 in the past 8 games, while cashing the Over at 7-2 clip in the previous 9 contests.

The 23 runs scored the past 2 days is the most scored in consecutive games by the Padres this season. The 2 routs come after a 5-game losing skid which saw the team average just 2.2 runs per game (RPG), cashing the Under in each outing.

Diamondbacks at Padres projected starters

RHP Scott McGough vs. RHP Adam Mazur

McGough (1-3, 6.35 ERA) makes his 1st start and 17th appearance. He has a 1.65 WHIP, 5.3 BB/9 and 5.8 K/9 in 17 IP.

  • Last start: No-decision, 2 1/3 IP, 0 ER, 1 H, 1 BB, 2 K in 40-pitch start at Padres in an 8-1 win Aug. 19, 2023
  • 2024 road splits: 0-2, 11.12 ERA (5 2/3 IP, 7 ER), 2.29 WHIP, .381 opponents’ batting average (OBA), 2 HR, 5 BB, 2 K in 6 relief appearances

Mazur (0-0, 1.50 ERA) makes his 2nd start. He has a 1.00 WHIP, 3.0 BB/9 and 6.0 K/9 in 6 IP.

  • Last start: No-decision, 6 IP, 1 ER, 2 H, 4 BB, 2 K in 4-2 road loss vs. Los Angeles Angels Tuesday in his Major League debut

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Diamondbacks at Padres odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:21 a.m. ET.

  • Moneyline (ML): Diamondbacks +110 (bet $100 to win $110) | Padres $130 (bet $130 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-196) | Padres -1.5 (+162)
  • Over/Under (O/U): 8.5 (O: -115 | U: -105)

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Diamondbacks at Padres picks and predictions

Prediction

Padres 8, Diamondbacks 3

Moneyline

The PADRES (-130) are a good play behind the rookie Mazur, who makes his home debut at Petco Park. He had a solid outing against the Angels in his 1st taste of the majors last time out.

The Diamondbacks (+110) counter with McGough, who has been a disaster in relief. He’ll serve as the opener, turning it over to an Arizona bullpen which has also been erratic, allowing 27 HR with a 4.48 ERA, which ranks 6th-worst in the majors.

Run line/Against the spread

It’s tough to trust a rookie making just his 2nd-ever start in the majors, but the PADRES -1.5 (+162) are worth a roll of the dice for the more adventurous bettor.

San Diego will get a shot at the shaky Diamondbacks +1.5 (-196) bullpen early in the game, and we could have another rout in the series finale.

Over/Under

OVER 8.5 (-115) is the play, based mostly on the poor pitching of McGough, and the fact the Padres have piled up 24 runs the past 2 games, and they’ll get to face the Diamondbacks for an extended period.

The Over is 4-1 in the past 5 games for the Diamondbacks, and 7-2 in the previous 9 outings. The Padres have hit the Over in 3 of the past 4 games at home.

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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Saturday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (30-34) and San Diego Padres (33-34) meet Saturday for the 3rd game of a 4-game series. First pitch from Petco Park is set for 8:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: San Diego leads 3-2

San Diego routed Arizona 10-3 in the 2nd game of the series Friday while cashing as a -135 home favorite. The Diamondbacks were trailing 5-3 at the end of the 7th inning, but the Padres scored 5 more runs in the 8th to put the game away.

RHP Michael King picked up the win, allowing just 4 hits and 1 walk with 5 K’s in 5 scoreless innings. Friday’s win ended a 5-game losing streak for the Padres.

Diamondbacks at Padres projected starters

RHP Ryne Nelson vs. RHP Matt Waldron

Nelson (3-4, 5.44 ERA) makes his 10th start. He has a 1.60 WHIP, 2.4 BB/9 and 6.0 K/9 in 48 innings.

  • Last start: No-decision, 7 2/3 IP, 2 ER, 6 H, 0 BB, 1 K in 4-2 home win over San Francisco Giants Monday
  • 2024 vs. San Diego: 1-0, 7.20 ERA (5 IP, 4 ER), 8 H, 1 BB, 3 K in 1 start, an 11-4 home win May 5
  • Career vs. San Diego: 2-2, 6.23 ERA (30 1/3 IP, 21 ER), 1.42 WHIP, 6.5 K/9 in 6 starts

Waldron (3-5, 3.98 ERA) makes his 13th start. The rookie has a 1.26 WHIP, 2.7 BB/9 and 9.1 K/9 in 63 1/3 innings.

  • Last start: No-decision, 6 1/3 IP, 1 ER, 2 H, 0 BB, 4 K in 2-1 loss at Los Angeles Angels Monday
  • 2024 vs. Arizona: 0-1, 21.00 ERA (3 IP, 7 ER), 8 H, 3 BB, 2 K in 1 start, an 11-4 road loss May 5
  • Career vs. Arizona: 0-2, 13.50 ERA (8 IP, 12 ER), 2.38 WHIP, 7.9 K/9 in 2 starts

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Diamondbacks at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:15 a.m. ET.

  • Moneyline (ML): Diamondbacks +120 (bet $100 to win $120) | Padres -145 (bet $145 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-175) | Padres -1.5 (+145)
  • Over/Under (O/U): 8 (O: -105 | U: -115)

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Diamondbacks at Padres picks and predictions

Prediction

Diamondbacks 5, Padres 3

Moneyline

LEAN DIAMONDBACKS (+120).

Arizona is 2-1 in its last 3 road games, while the Padres are only 1-2 in their last 3 at home. The Diamondbacks are also 3-1 in their last 4 meetings with the Padres in San Diego.

This is only a lean because Arizona is just 6-4 in the last 10 meetings. Arizona is also just 5-5 in its last 10 games overall, while the Padres are 4-6.

Run line/Against the spread

PASS.

I expect the Diamondbacks to cover as +1.5 (-175) underdogs, but the line is too heavy to risk betting on as currently set. Bet on the moneyline and/or O/U instead.

Over/Under

BET OVER 8 (-105).

The Over has hit in 3 of Arizona’s last 4 games overall and is 4-1 in its last 5 on the road. For San Diego, the Over is 2-1 in its last 3 home games. The Over has also hit in 3 of the last 4 Arizona-San Diego matchups overall and is 3-1 in the last 4 meetings in San Diego.

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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Friday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (30-33) and San Diego Padres (32-34) play the 2nd game of a 4-game set at Petco Park Friday. First pitch is scheduled for 9:40 p.m. ET . Let’s analyze FanDuel Sportsbook’s lines around the Diamondbacks vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 2-2

Arizona cashed as a slight road underdog (-105) against San Diego with a 4-3 victory Thursday. CF Corbin Carroll delivered 3 hits and scored 2 runs in the win, and RHP Kevin Ginkel picked up his 5th win of the season in relief. While the Diamondbacks pen has been so-so, having allowed the 3rd-most hits (231) in the NL, closer RHP Paul Sewald was able to record his 7th save while lowering his ERA to 0.87 in 10 1/3 IP.

San Diego got into a hole early, as 1B Christian Walker delivered an RBI double off RHP Randy Vasquez in the 1st inning and both 3B Eugenio Suarez and C Gabriel Moreno belted solo HRs in the 2nd. The Padres were able to tie the game in the 5th when C Kyle Higashioka homered, which was followed up by a 2-run RBI double from 1B Jake Cronenworth.

Diamondbacks at Padres projected starters

RHP Brandon Pfaadt vs. RHP Michael King

Pfaadt (2-4, 4.32 ERA) makes his 13th start. He has a 1.08 WHIP, 1.7 BB/9 and 8.8 K/9 in 73 innings.

  • Last start: No-decision, 6 IP, 4 ER, 5 H, 2 BB, 8 K in 5-4 win at New York Mets Sunday
  • 2024 vs. Padres: 0-1, 4.50 ERA (6 IP, 3 ER), 10 H (season high), 0 BB, 4 K in 1 start, a 13-1 home loss May 4

King (4-4, 3.82 ERA) makes his 13th start. He has a 1.08 WHIP, 2.0 BB/9 and 8.3 K/9 in 22 2/3 innings.

  • Last start: No-decision, 7 IP, 1 ER, 4 H, 2 BB, 4 K in 4-3 loss at Kansas City Royals Sunday
  • Sports highest HR-to-fly-ball percentage (16.7%) and HR/9 (1.6) in NL among qualified pitchers

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Diamondbacks at Padres odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:22 p.m. ET.

  • Moneyline (ML): Diamondbacks +102 (bet $100 to win $102) | Padres -120 (bet $120 to win $100
  • Run line (RL)/Against the spread (ATS): Diamondbacks -1.5 (+160) | Padres +1.5 (-194)
  • Over/Under (O/U): 7 (O: -114 | U: -106)

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Diamondbacks at Padres picks and predictions

Prediction

San Diego 4, Arizona 3

Moneyline

BET SAN DIEGO (-120).

King surrendered only 1 earned run in 7 innings in his last start against Kansas City, which enters Friday 11 games above .500. The former Yankee has shown the ability to dominate, as he took a no-hit bid into the 7th inning against Milwaukee April 17.

King’s ability to get pitches in the zone for quality strikes has improved. Expect Arizona, which over the last month has the 3rd-highest K% in MLB, to have a difficult time generating much offensively.

Run line

INCLUDE SAN DIEGO +1.5 (-205) IN A PARLAY. 

I like pairing the Padres +1.5 (-205) with the Chicago White Sox +1.5 (-178 at home vs. Boston Red Sox, 8:10 p.m. ET). Chicago has lost 14 in a row, but LHP Garrett Crochet is on the mound and the Red Sox lead MLB in K% vs. LHP (28.3%).

Over/Under

PASS.

Pfaadt leads all MLB qualified pitchers in 1st-pitch strike percentage (72.9%) and features a nasty sweeper that rates out as 3rd-best in the Stuff+ metric on Fangraphs. I would lean to the Under, but this number feels right.

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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Thursday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (29-33) and San Diego Padres (32-33) open a 4-game set Thursday. First pitch from Petco Park is scheduled for 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 2-1

The Diamondbacks snapped a 4-game winning streak with a 9-3 loss against the San Francisco Giants Wednesday while failing to cash as +104 home underdogs. RF Pavin Smith hit a solo shot in the 5th inning, and LHP Jordan Montgomery allowed 6 ER in 2 innings to pick up the loss.

The Padres have lost 4 games in a row after falling 3-2 against the Los Angeles Angels Wednesday and failing to cash as -174 road favorites. San Diego announced after the loss that 3B Manny Machado suffered a strained right hip flexor. RF Fernando Tatis Jr. had a 4-hit game for the 7th time in his career, while RHP Dylan Cease allowed 3 ER in 6 innings and picked up the loss.

Diamondbacks at Padres projected starters

RHP Slade Cecconi vs. RHP Randy Vasquez

Cecconi (1-4, 5.59 ERA) makes his 7th start. The rookie has a 1.05 WHIP, 2.0 BB/9 and 6.3 K/9 in 37 IP.

  • Last start: No-decision, 4 2/3 IP, 1 ER, 5 H, 0 BB, 4 K in 10-5 win at New York Mets Saturday
  • 2024 vs. Padres: 0-1, 12.46 ERA (4 1/3 IP, 6 ER), 5 H, 2 BB, 4 K in 1 start, a 7-1 home loss May 3
  • Career vs. Padres: 0-1, 9.00 ERA (6 IP, 6 ER), 1.33 WHIP, 7.5 K/9 in 1 start and 1 relief appearance

Vasquez (1-3, 5.74 ERA) makes his 7th start. The rookie has a 1.61 WHIP, 1.7 BB/9 and 6.1 K/9 in 26 2/3 IP.

  • Last start: Win, 5 IP, 3 ER, 4 H, 1 BB, 5 K in 7-3 victory at Kansas City Royals Saturday
  • Career vs. Diamondbacks: 0-0, 7.71 ERA (2 1/3 IP, 2 ER), 3 H, 2 BB, 2 K in 1 relief appearance of 7-1 home loss with New York Yankees Sept. 24, 2023

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Diamondbacks at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:25 a.m. ET.

  • Moneyline (ML): Diamondbacks +105 (bet $100 to win $105) | Padres -125 (bet $125 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-190) | Padres -1.5 (+155)
  • Over/Under (O/U): 8.5 (O: +100 | U: -120)

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Diamondbacks at Padres picks and predictions

Prediction

Padres 4, Diamondbacks 3

Moneyline

BET PADRES (-125).

The Diamondbacks have lost 6 of their last 10 games, including 4 of their last 6 on the road. They have allowed 4 or more runs in 5 of their last 6 games while scoring 4 or fewer in 6 of their last 10.

The Padres have won 3 of their last 4 home games and allowed 2 or fewer runs in 3 of their last 4 at Petco Park. They have also allowed 4 or fewer runs in each of their last 5 games.

Run line/Against the spread

PASS.

There is minimal value on the run line.

Over/Under

BET UNDER 8.5 (-120).

The Diamondbacks have held opponents to 4 or fewer runs in 5 of their last 10 games while scoring 4 or fewer in 6 of their last 10. San Diego has hit the Under in 7 of its last 10 games, including each of its last 4. It has scored 3 runs or fewer in each of its last 4 games while allowing 4 or fewer in each of its last 5.

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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Saturday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks and predictions.

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The Arizona Diamondbacks (39-51) face the San Diego Padres (51-41) Saturday for the middle game of a 3-game set in San Diego. First pitch is set for 8:40 p.m. ET at Petco Park. Let’s analyze Tipico Sportsbook‘s lines around the Diamondbacks vs. Padres odds with MLB picks and predictions.

Season series: Padres lead 8-2

The Diamondbacks lost Friday’s opener 5-3 and have dropped 3 straight. They are 2-7 in their last 9 games.

The Padres, who snapped a 3-game losing streak with the win, are 6-13 in their last 19 games.

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Diamondbacks at Padres projected starters

LHP Tyler Gilbert vs. LHP Sean Manaea

Gilbert (0-3, 5.33 ERA) makes his 6th start in 7 appearances. He has a 1.26 WHIP, 2.8 BB/9 and 6.0 K/9 through 25 1/3 IP.

  • D-backs are 1-4 in his 5 starts this season
  • Coming off his best start of the season, pitching 5 2/3 scoreless innings in a no-decision against the visiting Colorado Rockies Sunday
  • Career vs. Padres: 1-1, 1.69 ERA (16 IP, 3 ER), 9 H, 5 BB, 11 K in 2 starts and 1 relief appearance, all in 2021

Manaea (4-4, 4.09 ERA) makes his 17th start. He has a 1.21 WHIP, 3.4 BB/9 and 9.2 K/9 through 94 2/3 IP.

  • 2022 vs. Diamondbacks: 1-0, 2.37 ERA (19 IP, 5 ER), 7 H, 7 BB, 20 K in 3 starts – Padres went 2-1
  • 2022 home splits: 2-3, 4.54 ERA (39 2/3 IP, 20 ER), 1.44 WHIP, 8.2 K/9 in 7 starts

Diamondbacks at Padres odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:25 p.m. ET.

  • Money line (ML): Diamondbacks +160 (bet $100 to win $160) | Padres -200 (bet $200 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-135) | Padres -1.5 (+110)
  • Over/Under (O/U): 7.5 (O: -130 | U: +105)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Diamondbacks at Padres picks and predictions

Prediction

Padres 5, Diamondbacks 4

Money line

Arizona has struggled against San Diego this season, losing 8 out of 10. The D-backs have also lost 5 of their last 7 road games.

Manaea has pitched well against Arizona, while Gilbert has been inconsistent.

But at -200, this is a PASS. There are better bets to be made.

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Run line/Against the spread

The Diamondbacks are 50-40 ATS on the season, including 24-18 ATS on the road.

San Diego is only 15-29 ATS at home and 44-48 ATS overall.

While the D-backs have lost 7 of their last 9 games, they lost by 1 run in 4 of those losses.

Take the DIAMONDBACKS +1.5 (-135).

Over/Under

Six of this season’s 10 games between the teams this season have had 7 or fewer runs.

But 10 of the last 14 games for Arizona have had 8 or more runs.

The Padres’ last 6 games have all had 8 or more runs.

Take OVER 7.5 (-130).

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and soon IA. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Monday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks and predictions.

The Arizona Diamondbacks (32-36) open a 3-game road series against the San Diago Padres (41-27) Monday. First pitch is 9:40 p.m. ET at Petco Park. Let’s analyze Tipico Sportsbook‘s lines around the Diamondbacks vs. Padres odds with MLB picks and predictions.

The Padres lead the season series 3-1. This is the first matchup since their 4-game series to open the season.

The Diamondbacks went 3-3 in their recent homestand, winning 3 of the final 4 games and taking 2 of 3 contests from the Minnesota Twins over the weekend. They won 7-1 Sunday to capture the series.

The Padres start a 7-game homestand as they return after being swept in a 3-game series at the Colorado Rockies. They had won 4 in a row and 11 of 14 games before dropping the 3 games.

Diamondbacks at Padres projected starters

RHP Zach Davies vs. RHP Yu Darvish

Davies (2-3, 3.78 ERA) makes his 14th start. He has a 1.20 WHIP, 2.9 BB/9 and 7.4 K/9 through 69 IP.

  • Allowed 2 runs on 4 hits and 3 walks in 5 innings in his first start of the year against the Padres April 9; received a no-decision in a 5-2 loss.
  • Threw 7 scoreless innings in his last start vs. the Cincinnati Reds Tuesday and has not allowed a run in 2 of his last 3 starts.

Darvish (6-3, 3.35 ERA) makes his 13th start. He has a 0.97 WHIP, 1.8 BB/9 and 7.3 K/9 through 75 1/3 IP.

  • Faced the Diamondbacks in his first start of the season April 7 with 6 hitless innings and walked 4 in a 4-2 loss.
  • Has allowed only 1 run in his last 15 innings spanning 2 starts.

Diamondbacks at Padres odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:40 a.m. ET.

  • Money line (ML): Diamondbacks +145 (bet $100 to win $145) | Padres -180 (bet $180 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-155) | Padres -1.5 (+125)
  • Over/Under (O/U): 7.5 (O: +105 | U: -130)

Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!

Diamondbacks at Padres picks and predictions

Prediction

Padres 4, Diamondbacks 2

Money line

The Diamondbacks have won 3 of their last 4 games but are 6-9 in their last 15 contests. The magic number for them has been 5 runs. They are 13-2 in their last 15 games scoring 5 or more. They have lost 13 games in a row when they fail to score at least 5 runs.

The Padres have allowed 5 or more runs in 5 of their last 6 games but have allowed 4 or fewer runs in 9 of Darvish’s 12 starts this season.

I expect the Padres to win but it’s a PASS on the money line unless you include it as part of a parlay bet because of the price. As a single bet, it isn’t worth the action.

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Run line/Against the spread

The Diamondbacks are 39-29 ATS on the season, which is the third-best mark in baseball, and they are 20-12 ATS on the road. However, their last 5 road losses have been by 2 or more runs.

Of the Padres’ last 12 wins, 11 have been by at least 2 runs. But they are 10-20 ATS at home this season.

That said, I expect the Diamondbacks to struggle offensively against Darvish.

Take the PADRES -1.5 (+125).

Over/Under

Opponents have scored fewer than 5 runs in 3 of Davies’ last 4 starts but the Diamondbacks’ last 7 games have all had 8 or more total runs.

The Padres have had 6 straight games of 8 or more runs.

However, 3 of the 4 games between the two teams in April had 7 or fewer runs.

Take UNDER 7.5 (-130).

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO, NJ and soon IA. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Jess Root on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Additional MLB coverage:
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BaseballPress.com: Your source for every MLB lineup

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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Arizona Diamondbacks at San Diego Padres odds, picks and prediction

Analyzing Sunday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB picks and predictions.

The Arizona Diamondbacks (35-77) hope to secure a road series win Sunday against the San Diego Padres (63-49) in the rubber match of their three-game series. First pitch is 4:10 p.m. at Petco Park. Let’s analyze the lines around the Diamondbacks vs. Padres odds with MLB picks and predictions.

Diamondbacks LHP Madison Bumgarner (6-6, 4.57 ERA) makes his 17th start. He has a 1.15 WHIP, 2.2 BB/9 and 8.2 K/9 through 84 2/3 IP.

  • The Diamondbacks have won his last three starts. He has allowed only 5 earned runs in his last four outings, good for an ERA of 1.80 over 25 innings.
  • His only start of the season against San Diego was Opening Day. He allowed 6 earned run on 7 hits and 3 walks in 4 innings.

Padres LHP Blake Snell (5-4, 5.24 ERA) makes his 21st start. He has a 1.62 WHIP, 5.8 BB/9 and 11.2 K/9 through 89 1/3 IP.

  • He has won three of his last four decisions and the Padres have won five of his last six starts.
  • He has been either very good or pretty bad in his last seven starts. He has allowed 4 or more earned runs in 4 innings or less in three of them, while allowing 1 or zero runs in the other four.

Diamondbacks at Padres odds, lines, picks and prediction

MLB odds courtesy of Tipico Sportsbook; access USA TODAY Sports for a full list. Odds last updated at 10:39 a.m. ET.

  • Money line: Diamondbacks +180 (bet $100 to win $180) | Padres -220 (bet $220 to win $100)
  • Against the spread/ATS: Diamondbacks +1.5 (-120) | Padres -1.5 (-105)
  • Over/Under: 8.5 (O: -112 | U: -108)

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Prediction

Padres 5, Diamondbacks 3

Money line (ML)

The Diamondbacks have the second-fewest road wins this season and the third-lowest road winning percentage. They already won one game this series and have not won two games of any road series since taking two of three from the Atlanta Braves back April 23-25.

The Padres are tied for the second-most home wins this season. They have won five of Snell’s last six starts.

Take the PADRES (-220).

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Run line/Against the spread (ATS)

Of the Diamondbacks’ last 15 losses, 13 have been by at least two runs. They are only 24-32 ATS on the road.

Of the Padres’ last 13 wins, 10 have been by at least two runs. The Padres have beaten the Diamondbacks seven times this season, and only two of those games have been by only one run.

Take the Padres -1.5 (-105).

Over/Under (O/U)

Of the 11 games between the two teams this season, six have had totals of 9 or more runs. 54.2% of the games at Petco Park have gone Over the projected total.

However, this game is slated to be a bit of a pitching duel between the starters and will be decided when the bullpens come in.

Take UNDER 8.5 (-108).

For more sports betting picks and tips, visit SportsbookWire.com. Please gamble responsibly.

Follow Jess Root on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

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