Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Monday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

The Arizona Diamondbacks (2-2) visit the San Diego Padres (2-2) Monday with the 1st pitch at 9:40 p.m. ET at Petco Park.  Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Padres won 2022 season series 14-5

The Diamondbacks split a 4-game series at the Los Angeles Dodgers to start the season, winning 2-1 on Sunday. A 2-out, 9th-inning bunt single by OF Jake McCarthy drove in the winning run. Starter Zach Davies pitched 5 strong innings, allowing 1 ER, 4H, 2 BBs and 4 K’s.

The Padres split their opening series against the Colorado Rockies, winning the final 2 games. On Sunday, a 3-run HR by SS Xander Bogaerts in the 2nd inning was enough offense in a 3-1 win. Starter Seth Lugo went 7 innings and allowed only 1 run on 4 hits.

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Diamondbacks at Padres projected starters

RHP Ryne Nelson vs. LHP Ryan Weathers

Nelson was 1-1 with 1.47 ERA in 2022. He had a 0.82 WHIP, 2.9 BB/9 and 7.9 K/9 in 18 1/3 IP last season.

  • 2 of 3 starts as rookie were against Padres
  • 1-1 with 2.19 ERA against Padres in 12 1/3 IP

Weather was 0-0 with a  9.82 ERA in 2022. He had a 2.73 WHIP, 4 BB and 3 K through 3 2/3 IP.

  • Had 4.91 ERA in 5 spring training appearences
  • Is 0-1 with 6.75 ERA vs. Arizona in 4 appearances (2 starts)

Diamondbacks at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:41 a.m. ET.

  • Moneyline (ML): Diamondbacks +115 (bet $100 to win $115) | Padres -140 (bet $140 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-175) | Padres -1.5 (+145)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Diamondbacks at Padres picks and predictions

Prediction

Padres 4, Diamondbacks 3

Moneyline

The Diamondbacks were 2-7 in San Diego last season and 5-14 against the Padres overall.

Both teams will have their 5th starter on the mound so expect the bullpens to factor in early. San Diego’s bullpen only worked 2 innings in their win on Sunday, while Arizona’s pitched 4 innings and has gone 14 innings through 4 games.

The rested Padres relievers will be the difference.

BET PADRES (-140).

Run line/Against the spread

The Padres’ 2 wins were both by at least 2 runs while Arizona’s 2 losses have both been by at least 6 runs.

The Padres had baseball’s 2nd-worst home ATS record last season at 32-53 ATS.

Betting the Diamondbacks to cover isn’t as good a value at -175 as the Padres on the moneyline at -140, so PASS on this bet.

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Over/Under

Both teams have had 2 games of more than 8 runs and 2 of fewer than 8. Ten of their 19 games last season had fewer than 8 total runs.

BET UNDER 8 (-105).

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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Wednesday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks and predictions.

The Arizona Diamondbacks (65-70) close out their 3-game road series against the San Diego Padres (75-62) Wednesday. First pitch at Petco Park is 8:40 p.m. ET (FS1). Let’s analyze Tipico Sportsbook‘s lines around the Diamondbacks vs. Padres odds with MLB picks and predictions.

Season series: Padres lead 10-4 after splitting the first 2 games of series

The Diamondbacks’ bullpen blew another save Tuesday night as Ian Kennedy allowed 2 runs in the bottom of the 9th for a 6-5 loss. It was his 6th blown save the team’s 21st of the season. The loss was just their 3rd in their last 12 games.

The Padres snapped a 3-game losing streak with the win. They have 7 wins in their last 11 games and maintain a 3-game lead for the final NL wild-card berth.

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Diamondbacks at Padres projected starters

LHP Tommy Henry vs. RHP Yu Darvish

Henry (3-3, 4.83 ERA) makes his 7th start. He has a 1.48 WHIP, 4.5 BB/9 and 6.5 K/9 in 31 2/3 IP.

  • Rookie coming off his worst start, allowing 7 R on 8 H in 4 IP of an 18-2 loss to the Philadelphia Phillies Aug. 31
  • In 3 of his 4 starts prior to that outing, he allowed only 1 run.

Darvish (12-7, 3.26 ERA) makes his 26th start. He has a 0.97 WHIP, 1.7 BB/9 and 9.0 K/9 in 162 2/3 IP.

  • Struck out 9 and allowed only 2 H in 7 scoreless IP against the Los Angeles Dodgers in his last start Friday
  • Is 2-0 with 1.80 ERA in 3 starts against Arizona this season

Diamondbacks at Padres odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:09 a.m. ET.

  • Money line (ML): Diamondbacks +175 (bet $100 to win $175) | Padres -220 (bet $220 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-120) | Padres -1.5 (+100)
  • Over/Under (O/U): 7.5 (O: -130 | U: +105)

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Diamondbacks at Padres picks and predictions

Prediction

Padres 6, Diamondbacks 4

Money line

The Padres get to turn to Darvish in the series finale. He has dominated the Diamondbacks in 2022 and has been effective in his career against them.

Henry was knocked around in his last start against the Phillies.

While Arizona has played better recently, the D-backs are 28-36 on the road this season and are 25-40 against teams with winning records.

Their best chance to pick up a series win was Tuesday night with Merrill Kelly starting.

But with the price on Wednesday’s money line for the Padres, PASS and look to the spread and total for your bets.

Run line/Against the spread

The Padres are the league’s worst team at covering the spread at home this season at 21-44 ATS. They have failed to cover the spread in either of the first 2 games of the series.

However, 7 of the Padres’ 10 wins over the Diamondbacks have been by 2 or more runs.

The Diamondbacks are 10-2 ATS in their last 12 games and 80-55 ATS overall this season, but they have had ATS sweeps only 4 times all season and Darvish is one of the less likely pitchers to do it against, based on their performance against him this year.

Take the PADRES -1.5 (+100).

Over/Under

Nine of the 14 game between the 2 teams have had totals of 7 or fewer runs. The Diamondbacks have had totals of 7 or fewer runs in 4 of their last 6 games while 11 of Arizona’s last 16 have had 8 or more runs.

Five of the Padres’ last 6 have had 8 or more runs.

Five of Henry’s 6 starts have had totals of 8 or more runs.

Take OVER 7.5 (-130).

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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Tuesday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks and predictions.

The Arizona Diamondbacks (65-69) face the San Diego Padres (74-62) in the second game of their 3-game road series Tuesday. First pitch from Petco Park is at 9:40 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Diamondbacks vs. Padres odds with MLB picks and predictions.

Season series: Padres lead 9-4

The Diamondbacks shut out the Padres 5-0 in the opener Monday. Rookie RHP Ryne Nelson pitched 7 scoreless innings in his MLB debut to lead the Diamondbacks to their 9th win in their last 11 games.

The Padres have lost 3 straight games but won 6 of the 7 games prior to the skid. They have dominated the Diamondbacks this season, winning 9 of 13 games.

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Diamondbacks at Padres projected starters

RHP Merrill Kelly vs. RHP Joe Musgrove

Kelly (12-5, 2.84 ERA) makes his 28th start. He has a 1.11 WHIP, 2.6 BB/9 and 7.8 K/9 through 164 2/3 IP.

  • Is 1-0 against the Padres in 2022 with a 0.90 ERA over 2 starts.
  • Allowed 2 or fewer runs in 16 starts this season.

Musgrove (9-6, 3.01 ERA) makes his 25th start. He has a 1.04 WHIP, 1.9 BB/9 and 9.0 K/9 through 149 1/3 IP.

  • Recorded a win at Arizona April 9 with 2 ER over 6 IP
  • The Padres are 16-8 in his starts

Diamondbacks at Padres odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:11 a.m. ET.

  • Money line (ML): Diamondbacks +140 (bet $100 to win $140) | Padres -175 (bet $175 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-160) | Padres -1.5 (+130)
  • Over/Under (O/U): 7.5 (O: +112 | U: -140)

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Diamondbacks at Padres picks and predictions

Prediction

Diamondbacks 4, Padres 3

Money line

The Diamondbacks have been playing good baseball and have been getting great outings from their starters. Kelly didn’t allow a run in his last start and their starters have not allowed a run in their last 2 games. Arizona is 9-2 in its last 11 games.

The Padres have been consistently good when Musgrove pitches.

In a game where the final outcome could go either way because of good pitching, take the value here. BET the DIAMONDBACKS (+140).

Run line/Against the spread

The Padres have baseball’s worst home ATS record at 21-43 ATS.

The Diamondbacks are 39-24 ATS on the road this season, the 4th-best mark in all of baseball. They are 79-55 ATS overall this season, the 3rd-best mark in the league.

This one is probably the surer bet but pays out less. If you aren’t as confident with the money line, take the DIAMONDBACKS +1.5 (-160).

Over/Under

Nine of the 13 games between these teams have had 7 or fewer total runs.

Four of the Diamondbacks’ last 5 games have had 7 or fewer runs.

Take UNDER 7.5 (-140).

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Jess Root on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Additional MLB coverage:
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BaseballPress.com: Your source for every MLB lineup

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).

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