The Clemson Tigers (11-0) and South Carolina Gamecocks (4-7) play Saturday at Williams-Brice Stadium in Columbia, SC at 12 p.m. ET. We analyze the Clemson-South Carolina odds and betting lines while providing college football betting tips and advice on this matchup.
Clemson at South Carolina: Three things you need to know
1. Undefeated Clemson is ranked third in the polls as it tries to solidify its playoff ranking Saturday. The Tigers will play either Virginia or Virginia Tech in the ACC Championship game next week. Winning twice increases their chances of a higher seed.
2. South Carolina lost to Texas A&M 30-6 last week to drop its fourth contest in five games. This also ensured the Gamecocks would not be bowl eligible this season.
3. Tigers RB Travis Etienne steals the show. He leads the country in yards per carry at 8.73 and ranks seventh overall with 1,335 rushing yards.
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Clemson at South Carolina: Odds, betting lines and picks
Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 12:30 p.m. ET.
Prediction
Clemson 45, South Carolina 10
Moneyline (ML)
The moneyline wasn’t posted at the time of publishing. Due to the sizable spread in Clemson’s favor, the odds for the outright victory would be too chalky and not worth a wager.
Against the Spread (ATS)
Clemson is 8-3 against the spread overall and 3-1 on the road, coming in just 0.6 points per game above the line. South Carolina is 4-2 ATS at home and is four points above the projection line. South Carolina has fared poorly against ranked teams and hasn’t faced a team like Clemson this year.
Back the TIGERS (-26.5, -110). With QB Trevor Lawrence and Etienne, Clemson is too balanced to be slowed down by South Carolina.
Over/Under (O/U)
The projected total is 51.5. South Carolina will send this one over the number with some late, garbage-time points. The Tigers put up their points early and the OVER (+100) is our pick.
Get some action on this game or others, place a bet with BetMGM today. And for more sports betting picks and tips, visit SportsbookWire.com.
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