Carolina Panthers betting odds line spread pick predictions best bets – Page 4

Carolina Panthers at Miami Dolphins odds, picks and prediction

Analyzing Sunday’s Carolina Panthers at Miami Dolphins Week 12 odds and lines, with expert NFL picks, predictions and best bets.

The Carolina Panthers (5-6) visit the Miami Dolphins (4-7) on Sunday for a Week 12 matchup at Hard Rock Stadium in Miami Gardens, Fla. Kickoff is scheduled for 1 p.m. ET. Below, we look at the Panthers vs. Dolphins odds and lines, and make our best NFL picks, predictions and bets.

The Panthers were unable to follow up their 34-10 upset at the Arizona Cardinals two weeks ago with a win at home in Week 11. Carolina fell to the Washington Football Team by a 27-21 score in QB Cam Newton’s first start since re-signing with the team.

The Dolphins head into this one with a three-game win streak, averaging 21.0 points per game (PPG) while allowing 12.0 PPG during the impressive run. They’re 3-0-1 ATS in the previous four outings while hitting the Under in four straight.

Also see: All Week 12 odds and lines

Panthers at Dolphins odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 1:32 a.m. ET.

Money line: Panthers -130 (bet $130 to win $100) | Dolphins +105 (bet $100 to win $105)
Against the spread (ATS): Panthers -2.5 (-108) | Dolphins +2.5 (-112)
Over/Under (O/U): 41.5 (O: -112 | U: -108)

Panthers at Dolphins key injuries

Panthers

OG John Miller (ankle) out

Dolphins

S Brandon Jones (ankle, elbow) questionable
TE Adam Shaheen (knee) out

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Panthers at Dolphins odds, lines, predictions and picks

Prediction

Panthers 22, Dolphins 18

Money line

The PANTHERS (-130) aren’t priced too high if you just want to play them straight up and not worry about the points.

Against the spread

The PANTHERS -2.5 (-108) are a little cheaper if you think they can win by a field goal. This one is going to be a super close defensive battle. The Dolphins have looked good on defense lately, and the Panthers rank second in total yards per game allowed (288.7) and first against the pass (174.2).

Over/Under

The UNDER 41.5 (-108) is a low number, but points are going to be at a premium here. Each team has been playing strong defensively lately, and you can expect that to continue in South Florida Sunday.

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Underdog Corner: 3 best NFL picks and predictions for Week 12

Assessing the NFL betting odds and lines for Week 12, with three predictions and picks for the best underdog bets to make.

NFL point-spread favorites may have wound up winning Week 11, but we were undeterred here in Underdog Corner.
We hit with the Houston Texans and Indianapolis Colts, who both wound up posting double-digit outright road wins, to notch our second straight 2-1 against-the-spread weekend and improve to a very profitable 24-9 (.727) on the season. Additionally, 20 of our 24 underdog covers have wound up winning their games outright.
Now it’s on to Thanksgiving Week and our Week 12 outlook.

NFL underdog predictions: Week 12

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Wednesday at 3:30 p.m. ET.

Indianapolis Colts +3.5 (-125) vs. Tampa Bay Buccaneers

Yep, we’re right back on Indy drawing points again, and that has been a profitable play this year with the Colts owning a 5-2 ATS record as an underdog.

Overall, the Horseshoes are doing just fine as well, winning five of their last six to climb back above .500 at 6-5 and join the AFC’s jumbled playoff race.

Tom Brady and the Bucs throttled the visiting Giants 30-10 Monday night to end a two-game slide, but it has been a different story on the road this season for the defending champs, who are 2-3 SU and 0-5 ATS away from Raymond James Stadium.

Go with the red-hot COLTS (+3.5) catching the field goal plus a hook at home.

Miami Dolphins +2.5 (-108) vs. Carolina Panthers

These are two teams headed in the opposite directions, and the wrong side looks to be favored Sunday in South Beach.

The Dolphins have won and covered in three straight after a 1-7 SU, 2-5 ATS start while the Panthers are 2-6 SU/ATS after winning and covering their first three games.

Miami blitzed Lamar Jackson and the visiting Ravens into defeat two weeks ago and could do the same to Cam Newton and Carolina here. Take the DOLPHINS (+2.5) and the points and hit the Miami money line (+110) as well.

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Minnesota Vikings +3.5 (-117) at San Francisco 49ers

The Vikings are well-seasoned in close games with nine of their 10 contests so far being decided by one score or less, including five by three points or fewer.

Minnesota also is 3-2 SU and 5-0 ATS as an underdog this season.

The Niners, meanwhile, have won and covered in two straight to get back to .500 for the first time since Week 4.

However, San Fran is only 2-9 SU at home and 5-11 ATS as a favorite since the start of the 2020 season, and so the trends definitely peg the VIKINGS (+3.5) as the play here.

Also see: All Week 12 odds and lines

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Washington Football Team at Carolina Panthers odds, picks and prediction

Analyzing Sunday’s Washington Football Team at Carolina Panthers odds and lines, with expert NFL picks, predictions and best bets.

The Washington Football Team (3-6) visit the Carolina Panthers (5-5) on Sunday for a Week 11 game at Bank of America Stadium in Charlotte. Kickoff is scheduled for 1 p.m. ET. Below, we look at the Washington vs. Panthers odds and lines, and make our best NFL picks, predictions and bets.

Washington is coming off its most impressive showing of the season, a 29-19 win over the defending Super Bowl-champion Tampa Bay Buccaneers last week. That snapped an 0-4 SU/ATS run. The Under is 4-0 in the past four for WFT.

The Panthers won 34-10 at Arizona last week as seven-point underdogs, and Carolina is now 2-1 SU/ATS across the past three. QB Cam Newton will make the start, taking over for QB P.J. Walker, who started last week in place of the injured QB Sam Darnold (scapula).

Also see: All Week 11 odds and lines

Washington at Panthers odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 9:30 a.m. ET.

Money line: Washington +145 (bet $100 to win $145) | Panthers -180 (bet $180 to win $100)
Against the spread (ATS): Washington +3.5 (-117) | Panthers -3.5 (-103)
Over/Under (O/U): 42.5 (O: -117 | U: -103)

Washington at Panthers key injuries

Washington

WR Curtis Samuel (groin) questionable
TE Ricky Seals-Jones (hip) out

Panthers

No notable injuries to report

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Washington at Panthers odds, lines, predictions and picks

Prediction

Panthers 24, Washington 19

Money line

PANTHERS (-180) is not terribly out of line if you just want to back Newton and the home team without worrying about laying the points.

Against the spread

The PANTHERS -3.5 (-103) welcome Newton back under center, and welcome former head coach Ron Rivera to town. There are all kinds of interesting storylines in this game, and Washington +3.5 (-117) is riding high after an upset of the Bucs last week, too.

I think the crowd is going to be electric in Charlotte with Cam making his first start with the team since re-signing, and they’ll hold off Washington. Three-and-a-hook is not a great spread, so play it lightly. I actually like the money line much better in what should be a close game.

Over/Under

The OVER 42.5 (-117) is the lean, ever so slightly. The Panthers offense is averaging just 20.5 PPG, ranking 21st in the NFL this season. And the defense is yielding just 19.3 PPG, which is sixth in the NFL. This defense is nasty, and will give QB Taylor Heinicke and the Washington offense trouble. But Cam and the Panthers should be able to do enough, and WFT likely will score late to inch this one over the finish line.

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Carolina Panthers at Arizona Cardinals odds, picks and prediction

Analyzing Sunday’s Carolina Panthers at Arizona Cardinals odds and lines, with expert NFL picks, predictions and best bets.

The Carolina Panthers (4-5) face the Arizona Cardinals (8-1) on the road Sunday in Week 10. Kickoff at State Farm Stadium is set for 4:05 p.m. ET. Below, we look at the Panthers vs. Cardinals odds and lines, and make our best NFL picks, predictions and bets.

The Panthers have lost five of their last six games following a 3-0 start to the season. They have weathered injuries to RB Christian McCaffrey and now QB Sam Darnold, who suffered a fractured scapula and was placed on injured reserve. QB Cam Newton signed with the team this week but will not start this week as the team has opted to roll out QB P.J. Walker under center.

Arizona is the top seed in the NFC but is dealing with injuries of their own. QB Kyler Murray and WRs DeAndre Hopkins and A.J. Green were out in Week 9, but QB Colt McCoy led them to a 31-17 win over the San Francisco 49ers. They have the second-ranked scoring offense in the NFL (30.8 points per game) and the third-best scoring defense (17.2 points per game allowed).

Panthers at Cardinals odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 8:12 a.m. ET.

Money line: Panthers +330 (bet $100 to win $330) | Cardinals -450 (bet $450 to win $100)
Against the spread (ATS): Panthers +8.5 (-108) | Cardinals -8.5 (-112)
Over/Under (O/U): 43.5 (O: -105 | U: -115)

Panthers at Cardinals key injuries

Panthers

DE Brian Burns (ankle) questionable
CB Rashaan Melvin (hand) out
QB Sam Darnold (shoulder) injured reserve

Cardinals

RB Chase Edmonds (ankle) out
OL Justin Pugh (calf) out
QB Kyler Murray (ankle) questionable
WR DeAndre Hopkins (hamstring) questionable
S Budda Baker (knee) questionable
WR Rondale Moore (neck) questionable
DE Jordan Phillips (groin) questionable

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Panthers at Cardinals odds, lines, predictions and picks

Prediction

Cardinals 30, Panthers 12

Money line

PASS on the money line. The Cardinals are going to take care of business and it isn’t worth the money to gain so little. Carolina allows the second-fewest yards per game in the league (293.1) but they do not have the offense to keep up with the Cardinals, especially with Walker at quarterback. They are turnover-prone and the Cardinals are one of the top defenses in the league in creating takeaways.

Against the spread

The Cardinals are 7-2 ATS this season, while the Panthers are 4-5 ATS and 2-2 ATS on the road.

Six of the Cardinals’ eight wins have been by at least 12 points. They have scored over 30 points seven times and allowed 20 or fewer seven times.

The only way the Panthers keep this game close is by not turning the ball over, creating multiple turnovers and using the run game to slow the game down. Short of all those things happening, the Cardinals are the way to go.

Take the CARDINALS -8.5 (-112).

Over/Under

Only two of the Panthers’ games this season have gone Over the projected total this season. Four of the Cardinals’ nine games have.

The Panthers have not cracked 20 points in their last three outings and in two of them, they scored 6 or fewer points. The Cardinals will get around the 30 points they have been scoring. The question is whether the Panthers can score more than 13 points against this Arizona defense.

Take UNDER 43.5 (-115).

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New England Patriots at Carolina Panthers odds, picks and prediction

Analyzing Sunday’s New England Patriots at Carolina Panthers odds and lines, with expert NFL picks, predictions and best bets.

Winners of two straight, the New England Patriots (4-4) are on the road against the Carolina Panthers (4-4). They face one another Sunday at 1 p.m. ET at Bank of America Stadium. Below, we look at the Patriots vs. Panthers odds and lines, and make our best NFL picks, predictions and bets.

The New England defense picked off QB Justin Herbert twice, with S Adrian Phillips returning one for a touchdown, while K Nick Folk make four field goals in a 27-24 win over the Los Angeles Chargers. Rookie QB Mac Jones has not turned the ball over the last two games.

The Panthers snapped a four-game losing streak last week with a 19-13 win over the Atlanta Falcons. The defense held Atlanta to 213 yards of offense and picked off QB Matt Ryan twice in the win.

Patriots at Panthers odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 11:25 p.m. ET.

Money line: Patriots -190 (bet $190 to win $100) | Panthers +155 (bet $100 to win $155)
Against the spread (ATS): Patriots -3.5 (-105) | Panthers +3.5 (-115)
Over/Under (O/U): 41.5 (O: -105 | U: -115)

Patriots at Panthers key injuries

Patriots

K Nick Folk (knee) questionable
WR N’Keal Harry (knee) questionable
LB Dont’a Hightower (ankle) questionable
G Shaq Mason (abdomen) questionable
TE Jonnu Smith (shoulder) questionable

Panthers

QB Sam Darnold (concussion, shoulder) questionable
G Pat Elflein (hamstring) questionable

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Patriots at Panthers odds, lines, predictions and picks

Prediction

Patriots 21, Panthers 17

Money line

The Patriots are 3-0 on the road this season. Jones is taking care of the football, while the Panthers have been in a tailspin.

QB Sam Darnold has not had a passing touchdown in his last two games. The Panthers are No. 2 in total defense and allow the fifth-fewest points in the league.

But Jones will continue to be effective and to protect the football.

Take the Patriots (-190).

Against the spread

Both teams are 4-4 ATS this season, but the Pats have covered the spread in their last two games, while the Panthers, before their win over the Falcons last week, had failed to cover the spread in four straight games.

The Pats are 2-3 ATS as a favorite.

I expect this to be close and come down to the wire.

Take the PATRIOTS -3.5 (-105).

Over/Under

The Patriots have had each of their last four games hit the Over.

Only two of the Panthers’ games this season have not gone Under the projected total.

This will be a defensive battle between two top-10 defensive teams.

Take UNDER 41.5 (-115).

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Carolina Panthers at Atlanta Falcons odds, picks and prediction

Analyzing Sunday’s Carolina Panthers at Atlanta Falcons Week 8 odds and lines, with expert NFL picks, predictions and best bets.

The Carolina Panthers (3-4) hit the road in Week 8 to face the NFC South division-rival Atlanta Falcons (3-4) Sunday at Mercedes-Benz Stadium. Kickoff is scheduled for 1 p.m. ET and will be televised on FOX. Below, we look at the Panthers vs. Falcons odds and lines, and make our best NFL picks, predictions and bets.

The Panthers opened the season 3-0 SU/ATS, but Carolina is just 0-4 SU/ATS across its past four. It hit rock-bottom last week on the road against the New York Giants, falling 25-3 as QB Sam Darnold was benched.

The Falcons have bounced back from an 0-2 SU/ATS start to go 3-1 SU/ATS across the past four. That includes a 30-28 comeback victory last Sunday in Miami as 1.5-point favorites. The Over has cashed in three straight.

Panthers at Falcons odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 10:20 a.m. ET.

Money line: Panthers +133 (bet $100 to win $133) | Falcons -165 (bet $165 to win $100)
Against the spread (ATS): Panthers +3.5 (-130) | Falcons -3.5 (+105)
Over/Under (O/U): 46.5 (O: -112 | U: -108)

Panthers at Falcons key injuries

Panthers

RB Christian McCaffrey (hamstring) out
CB CJ Henderson (shoulder) questionable
LB Shaq Thompson (foot) questionable

Falcons

No major injuries to report

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Panthers at Falcons odds, lines, predictions and picks

Prediction

Falcons 26, Panthers 20

Money line

ATLANTA (-165) is a worth a play on the money line at home as Carolina (+133) has been horrific lately. On the flip side, the Falcons have been playing very good football, and the offense has scored 27 or more points in three straight outings.

Against the spread

The FALCONS -3.5 (+105) is an attractive play at plus-money, although I’ve never been a huge fan of three-and-a-hook. However, the Panthers +3.5 (-130) offense was terrible last week, and the defense has been dismal and showing no signs of life lately. Carolina has allowed 29.0 PPG across the past four games after yielding just 10.0 PPG in the first three games.

Over/Under

The UNDER 46.5 (-108) is worth a look in this one, but it’s only worth a small-unit play. Both defenses have been very giving, but Carolina’s offense bottomed out last week, and it’s uncertain what we’ll get. The Under is 12-3-1 in the past 16 meetings in this series, so that’s the way to go until these teams reverse the trend.

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Carolina Panthers at New York Giants odds, picks and prediction

Analyzing Sunday’s Carolina Panthers at New York Giants Week 7 odds and lines, with expert NFL picks, predictions and best bets.

The Carolina Panthers (3-3) travel to meet the New York Giants (1-5) at MetLife Stadium Sunday for a Week 7 game. Kickoff is scheduled for 1 p.m. ET and the game is televised on FOX. Below, we look at the Panthers vs. Giants odds and lines, and make our best NFL picks, predictions and bets.

The Panthers opened the season 3-0 straight up (SU) and 3-0 against the spread (ATS), but they have crashed back to Earth with an 0-3 SU/ATS skid across the past three outings. QB Sam Darnold returns to the stadium he called home when he was with the New York Jets from 2018-20.

The Giants were roughed up 38-11 at home, the first time that has even been a final in NFL history. New York slipped to 0-3 SU/ATS in three home games with the Under going 2-0-1 in those outings.

Panthers at Giants odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 8:33 a.m. ET.

Money line: Panthers -155 (bet $155 to win $100) | Giants +125 (bet $100 to win $125)
Against the spread (ATS): Panthers -2.5 (-130) | Giants +2.5 (+105)
Over/Under (O/U): 42.5 (O: -108 | U: -112)

Panthers at Giants key injuries

Panthers

OT Cam Erving (neck, illness) questionable
WR Terrace Marshall Jr. (concussion) out
LB Shaq Thompson (foot) out

Giants

RB Saquon Barkley (ankle) out
TE Evan Engram (calf) questionable
WR Kenny Golladay (knee) out
WR John Ross (hamstring) questionable
WR Darius Slayton (hamstring) questionable
WR Sterling Shepard (hamstring) questionable
WR Kadarius Toney (ankle) out

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Panthers at Giants odds, lines, predictions and picks

Prediction

Panthers 23, Giants 16

Money line

The PANTHERS (-155) are a decent play at this price as it isn’t terribly out of line if you don’t want to worry about laying the points. Yes, Carolina has lost three in a row, but the Giants could be the elixir to cure the Panthers’ ills.

Against the spread

The PANTHERS -2.5 (-130) is a little on the expensive side, so you might just want to play the money line. Carolina is the play because of its defense, and the fact New York is so banged up.

The Panthers rank third in the NFL with just 308.3 total yards per game allowed, and Carolina is second in the league with just 196.8 passing yards per game.

The Panthers have allowed just 20.2 PPG. That will be the difference here.

Over/Under

The UNDER 42.5 (-112) is the lean based upon New York’s rash of injuries, and Carolina’s sturdy defense.

The Under has hit in four straight for the Panthers as favorites, and is 6-1 in the previous seven as road faves. The Under is 10-3-1 for the G-Men dating back to last season, and 5-0-1 in the past six as home dogs.

Week 7 best bets

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Minnesota Vikings at Carolina Panthers odds, picks and prediction

Analyzing Sunday’s Minnesota Vikings at Carolina Panthers odds and lines, with expert NFL picks, predictions and best bets.

The Minnesota Vikings (2-3) look to get to .500 for the first time this season when they travel to play the Carolina Panthers (3-2), who are looking to avoid a third straight loss, when they meet at 1 p.m. ET Sunday at Bank of America Stadium. Below, we look at the Vikings vs. Panthers odds and lines, and make our best NFL picks, predictions and bets.

Minnesota needed a 54-yard field goal as time expired at home against the Detroit Lions to avoid dropping to 1-4 last week. While top offensive stars Dalvin Cook, Justin Jefferson and Adam Thielen have all been nursing injuries, none are listed on the final injury report.

The same can’t be true for the Panthers, who will be without star running back Christian McCaffrey after he suffered a setback from a hamstring injury this week in practice. McCaffrey is critical to the Panthers’ success, as evidenced by Carolina being 3-0 in games he has played and 0-2 in games he hasn’t.

Vikings at Panthers odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 10:10 a.m. ET.

Money line: Vikings -140 (bet $140 to win $100) | Panthers +115 (bet $100 to win $115)
Against the spread (ATS): Vikings -2.5 (-117) | Panthers +2.5 (-103)
Over/Under (O/U): 44.5 (O: -115 | U: -105)

Vikings at Panthers key injuries

Vikings

DT Michael Pierce (elbow) out

Panthers

RB Christian McCaffrey (hamstring) out
LB Shaq Thompson (foot) out
LB Kamal Martin (concussion) out
G Deonte Brown (knee) questionable
CB C.J. Henderson (shoulder) questionable

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Vikings vs. Panthers odds, lines, predictions and picks

Prediction

Vikings 24, Panthers 20

Money line

You get a better return on the Vikings with the spread, which is less than a field goal. Personally, I would avoid this if you’re betting on Minnesota and get the better return laying 2.5, but if pressed, I would lay it with the VIKINGS (-140).

Against the spread

The Vikings are at full strength for the first time this season after seeing stars Anthony Barr and Cook both missing time in the early portion of the season.

The same rationale that was in play with the money line comes into play here. If you’re expecting a team to win, you’re likely expecting them to win by a field goal or more. Even if the game goes to overtime, if there’s a winner, it will be by more than 2.5 points.

Take the VIKINGS -2.5 (-117)

Over/Under

There are only two games on the Week 6 schedule that have lower Over/Unders than this one and there’s a reason it’s only 44.5 points.

Minnesota overhauled its defense with veterans and the group started slow. But, in their last three games, Minnesota has allowed 17 points or less.

The Panthers have made it tough on opposing quarterbacks, who are averaging less than 200 yards a game, so Kirk Cousins won’t have it easy.

If McCaffrey was playing, I would likely have a different view of this, but he’s not, so take UNDER 44.5 (-105)

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Philadelphia Eagles at Carolina Panthers odds, picks and prediction

Analyzing Sunday’s Philadelphia Eagles at Carolina Panthers odds and lines, with expert NFL picks, predictions and best bets.

The Philadelphia Eagles (1-3) travel to meet the Carolina Panthers (3-1) at Bank of America Stadium Sunday of Week 5. Kickoff is scheduled for 1 p.m. ET and the game is televised on FOX. Below, we look at the Eagles vs. Panthers odds and lines, and make our best NFL picks, predictions and bets.

The Eagles came up short at home against the Kansas City Chiefs in Week 4, losing 42-30. Not only was it the third straight loss for Philly, it failed to cover the spread for the third consecutive outing, too. The Over cashed in each of the last two for the Eagles, as they yielded 83 total points.

The Panthers suffered their first setback of the season against the Dallas Cowboys in Week 4, falling 36-28 on the road. It was also the first non-cover for Carolina, and its first Over result after three consecutive Unders.

Eagles at Panthers odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 9:20 a.m. ET.

Money line: Eagles +133 (bet $100 to win $133) | Panthers -165 (bet $165 to win $100)
Against the spread (ATS): Eagles +3.5 (-130) | Panthers -3.5 (+105)
Over/Under (O/U): 45.5 (O: -115 | U: -105)

Eagles at Panthers key injuries

Eagles

OT Lane Johnson (personal) out

Panthers

RB Christian McCaffrey (hamstring) doubtful
LB Shaq Thompson (foot) out
OT Cameron Erving (neck) out
DE Yetur Gross-Matos (ankle) questionable

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Eagles at Panthers odds, lines, predictions and picks

Prediction

Panthers 23, Eagles 20

Money line

Taking the PANTHERS (-165) straight up and forgetting about the laying the points isn’t a bad idea. The cost for Carolina isn’t terribly out of line.

Against the spread

The EAGLES +3.5 (-130) are worth a small-unit play. The Panthers aren’t blowing anyone out, and it’s not a good idea to lay the three and a hook, even at home.

I just don’t trust Carolina’s offense, especially without McCaffrey, and it appears CMC will sit at least one more week.

Over/Under

It’s all about the UNDER 45.5 (-105) in this battle in Charlotte. The Panthers have allowed just 251.5 total yards per game, to rank third in the NFL, and they’re also third with just 16.5 points per game allowed.

They’re hard on the run, too, allowing just 95.0 rushing yards per game, so QB Jalen Hurts might have a tough time getting going. Expect defense to reign supreme.

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Carolina Panthers at Dallas Cowboys odds, picks and prediction

Analyzing Sunday’s Carolina Panthers at Dallas Cowboys odds and lines, with expert NFL picks, predictions and best bets.

The Carolina Panthers (3-0) and Dallas Cowboys (2-1) meet at AT&T Stadium in Arlington, Texas in Week 4. Kickoff is scheduled for 1 p.m. ET. Below, we look at the Panthers vs. Cowboys odds and lines, and make our best NFL picks, predictions and bets.

The Panthers have surprised with three victories through three outings, including a win last time they were in the state of Texas in Week 3. Carolina won 24-9 and covered as an 8-point favorite against the Houston Texans last week. The Panthers are 3-0 against the spread and the Under is also 3-0.

Carolina ranks first in total yards allowed per game (191.0), passing yards allowed (146.0) and rushing yards allowed (45.0). Its 10.0 PPG allowed ranks second in the NFL.

The Cowboys are also 3-0 ATS, going for 416.7 total yards per game to rank fifth in the NFL. The run game has been solid, too, averaging 139.3 yards per game to rank fourth. They’re also putting up 30.0 PPG, so they’ll easily be the biggest test for the Panthers so far.

Panthers at Cowboys odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 9:30 a.m. ET.

Money line: Panthers +165 (bet $100 to win $165) | Cowboys -205 (bet $205 to win $100)
Against the spread (ATS): Panthers +4.5 (-115) | Cowboys -4.5 (-107)
Over/Under (O/U): 51.5 (O: -115 | U: -105)

Panthers at Cowboys key injuries

Panthers

DE Yetur Gross-Matos (ankle) doubtful
RB Christian McCaffrey (hamstring) out
G John Miller (shoulder) questionable

Also see: On Site

Cowboys

DE Randy Gregory (knee) questionable
OT Ty Nsekhe (illness) out
DE Dorance Armstrong (ankle) out
DE Carlos Watkins (knee) out
S Donovan Wilson (groin) out

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Panthers at Cowboys odds, lines, predictions and picks

Prediction

Cowboys 26, Panthers 17

Money line

The Cowboys (-205) will cost you more than two times your potential return, and that’s just too expensive against an undefeated team.

AVOID, and look to the spread instead.

Against the spread

The COWBOYS -4.5 (-107) are the play at home. Yes, the Panthers are unbeaten, but real only real quality victory was the win in Week 2 against the visiting New Orleans Saints. The New York Jets are winless, and the Houston Texans have just one win.

Toss in the fact the Panthers are missing their best player, McCaffrey, and it’s going to be the longest day at the office for Carolina to date.

Over/Under

UNDER 51.5 (-105) is the best play on the board. The Panthers have been tremendous defensively, while the Cowboys have also managed to keep the opposition down. This won’t be a defensive slog, but it also won’t be an offensive shootout with tons of fireworks.

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