St. Louis Cardinals at Boston Red Sox odds, picks and predictions

Analyzing Sunday’s St. Louis Cardinals at Red Sox odds and lines, with MLB expert picks, predictions and best bets.

The St. Louis Cardinals (15-25) finish their 6-game road trip and a 3-game series at the Boston Red Sox (22-18) on Sunday Night Baseball. First pitch from Fenway Park is at 7 p.m. ET (ESPN). Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Cardinals lead 2-0

After a sad start to their season the Cardinals have won 5 of their last 6 games while the Red Sox have lost 4 of 5. Saturday’s game showed off the opposite streaks the Red Sox and Cardinals are on.

Down 3-1 in the 9th inning, the Cardinals rallied for 3 runs as Kenley Jansen blew a ninth-inning lead for the 2nd straight day. SS Kiké Hernández threw away a potential game-ending double play as the Cardinals won 4-3 and look to sweep the Red Sox on Sunday.

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Cardinals at Red Sox projected starters

RHP Miles Mikolas vs. RHP Corey Kluber

Mikolas (1-1, 5.40 ERA) makes his 9th start. He has a 1.65 WHIP, 2.6 BB/9 and 8.9 K/9 in 41 2/3 innings.

  • Last start: No decision, 4 1/3 IP, 1 ER, 4 H, 3 B, 7 K in 3-1 win at the Chicago Cubs on Monday
  • Has .274 opponent BA in road starts vs .370 average at home

Kluber (2-4, 6.29 ERA) makes his 8th start. He has a 1.39 WHIP, 3.1 BB/9 and 7.3 K/9 in 34 1/3 innings.

  • Last start: Win, 5 IP, 3 ER, 7 H, 0 BB, 1 K in 7-4 victory at the Philadelphia Phillies May 6
  • First batters of the game vs. Kluber have a collective 1.57 OPS. The remaining leadoff hitters have just a .849 OPS

Cardinals at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:23 a.m. ET.

  • Moneyline (ML): Cardinals -120 (bet $120 to win $100) | Red Sox +100 (bet $100 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals -1.5 (+125) | Red Sox +1.5 (-155)
  • Over/Under (O/U): 10.5 (O: -105 | U: -115)

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Cardinals at Red Sox picks and predictions

Prediction

Cardinals 8, Red Sox 5

Moneyline

The Red Sox are 0-7 in their last 7 interleague games. And the last 2 times Boston was a game away from being swept, they got swept.

BET CARDINALS -120.

Run line/Against the spread

After a loss, Boston is 7-10 ATS season and while St. Louis hasn’t been great, it covers more often than not (11-10) on the road. The Cardinals have scored 12 runs in the 2 games and, if you like the Cardinals to win, you should like them to win by multiple runs.

BET CARDINALS -1.5 (+125).

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Over/Under

Trends point toward the Over. Boston leads MLB in Overs at 26-13-1 (66.7%). The Over is 10-4 for the Cardinals in interleague games this season.

The books expect a high-scoring game and while 10.5 is well above the average total line, I’m siding with the house.

LEAN OVER 10.5 (-105).

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St. Louis Cardinals at Boston Red Sox odds, picks and predictions

Analyzing Friday’s St. Louis Cardinals at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

The St. Louis Cardinals (13-25) and Boston Red Sox (22-16) open a 3-game set at Fenway Park Friday. First pitch is at 7:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting between the teams who met in the 2013 World Series; the Red Sox won 2-1 in 2022

After snapping an 8-game losing streak, the Cardinals won 3 in a row before falling 10-4 to the Chicago Cubs Wednesday. The Cards offense has been OK at 11th with 4.56 runs/9 and 9th with a .258 BA. It’s their pitching that has been atrocious at 24th in baseball with a 5.40 ERA from the starters. They are just 6-14 in the last 20 games, but remain just 8 games out in a weak NL Central.

The Red Sox have picked it up of late, winners of 8 of the last 10 games. They’re led by an offense ranked 3rd (5.80) in runs/9, 4th (.269) in BA and 3rd (.789) in OPS. Their starting pitching has been bad, too, ranking 28th with a 6.01 ERA.

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Cardinals at Red Sox projected starters

RHP Adam Wainwright vs. LHP James Paxton

Wainwright (0-0, 7.20 ERA) makes his 2nd start. He has a 1.60 WHIP, 0.0 BB/9 and 9.0 K/9 in 5 innings.

  • Last start Saturday vs. Detroit Tigers: 5 IP, 4 ER, 8 H, 0 BB, 5 K; only allowed 2 H and 0 ER in 1st 4 IP, but faltered in the 5th.
  • Last start vs. Red Sox June 17: 6 1/3 IP, 4 ER, 7 H, 1 BB, 5 K

Paxton (0-0, 0.00 ERA) makes his 1st start due to a hamstring injury. He has pitched just 21 2/3 IP since 2019 due to injuries with a 6.65 ERA.

  • Was 2-3 with a 6.23 ERA in 6 games (5 starts) at Triple-A Worchester with a 1.57 WHIP and 26 K in 21 2/3 IP
  • Last start vs. Cardinals came in 2016: 5 IP, 5 ER, 8 H, 2 BB, 7 K

Cardinals at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:38 a.m. ET.

  • Moneyline (ML): Cardinals +100 (bet $100 to win $100) | Red Sox -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-180) | Red Sox -1.5 (+150)
  • Over/Under (O/U): 11 (O: -105 | U: -115)

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Cardinals at Red Sox picks and predictions

Prediction

Red Sox 7, Cardinals 5

Moneyline

Boston has had St. Louis’ number in the minimal sample size, winning 2 of 3 last year and sweeping a 4-game series in 2017. They are similar teams, but Boston is doing it better with bad starting pitching, and the Red Sox have a better bullpen at 8th with a 3.42 ERA vs. St. Louis’ 16th-ranked pen at 3.88. The Red Sox are 13-7 at home.

Take the RED SOX (-120) at an undervalued number.

Run line/Against the spread

Boston is 22-16 on the RL and 11-9 at home. Six of their last 8 wins have been by multiple runs, and the fact they’re using a pitcher making his 1st start of the year doesn’t scare me away. St. Louis is 3-5 against lefties as well.

Take the RED SOX -1.5 (+150).

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Over/Under

It’s slated to be 77 degrees with an 8-mph wind blowing out to right-center. The Over is 5-0 in the Cardinals’ last 5 following a loss and in their last 5 interleague games. The Over is 4-0 in the Red Sox’s last 4 home games and home games against a righty.

Take the OVER 11 (-105).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Ryan Dodson on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Additional MLB coverage:
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BaseballPress.com: Your source for every MLB lineup

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