St. Louis Cardinals at Boston Red Sox odds, picks and predictions

Analyzing Friday’s St. Louis Cardinals at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

The St. Louis Cardinals (13-25) and Boston Red Sox (22-16) open a 3-game set at Fenway Park Friday. First pitch is at 7:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting between the teams who met in the 2013 World Series; the Red Sox won 2-1 in 2022

After snapping an 8-game losing streak, the Cardinals won 3 in a row before falling 10-4 to the Chicago Cubs Wednesday. The Cards offense has been OK at 11th with 4.56 runs/9 and 9th with a .258 BA. It’s their pitching that has been atrocious at 24th in baseball with a 5.40 ERA from the starters. They are just 6-14 in the last 20 games, but remain just 8 games out in a weak NL Central.

The Red Sox have picked it up of late, winners of 8 of the last 10 games. They’re led by an offense ranked 3rd (5.80) in runs/9, 4th (.269) in BA and 3rd (.789) in OPS. Their starting pitching has been bad, too, ranking 28th with a 6.01 ERA.

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Cardinals at Red Sox projected starters

RHP Adam Wainwright vs. LHP James Paxton

Wainwright (0-0, 7.20 ERA) makes his 2nd start. He has a 1.60 WHIP, 0.0 BB/9 and 9.0 K/9 in 5 innings.

  • Last start Saturday vs. Detroit Tigers: 5 IP, 4 ER, 8 H, 0 BB, 5 K; only allowed 2 H and 0 ER in 1st 4 IP, but faltered in the 5th.
  • Last start vs. Red Sox June 17: 6 1/3 IP, 4 ER, 7 H, 1 BB, 5 K

Paxton (0-0, 0.00 ERA) makes his 1st start due to a hamstring injury. He has pitched just 21 2/3 IP since 2019 due to injuries with a 6.65 ERA.

  • Was 2-3 with a 6.23 ERA in 6 games (5 starts) at Triple-A Worchester with a 1.57 WHIP and 26 K in 21 2/3 IP
  • Last start vs. Cardinals came in 2016: 5 IP, 5 ER, 8 H, 2 BB, 7 K

Cardinals at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:38 a.m. ET.

  • Moneyline (ML): Cardinals +100 (bet $100 to win $100) | Red Sox -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-180) | Red Sox -1.5 (+150)
  • Over/Under (O/U): 11 (O: -105 | U: -115)

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Cardinals at Red Sox picks and predictions

Prediction

Red Sox 7, Cardinals 5

Moneyline

Boston has had St. Louis’ number in the minimal sample size, winning 2 of 3 last year and sweeping a 4-game series in 2017. They are similar teams, but Boston is doing it better with bad starting pitching, and the Red Sox have a better bullpen at 8th with a 3.42 ERA vs. St. Louis’ 16th-ranked pen at 3.88. The Red Sox are 13-7 at home.

Take the RED SOX (-120) at an undervalued number.

Run line/Against the spread

Boston is 22-16 on the RL and 11-9 at home. Six of their last 8 wins have been by multiple runs, and the fact they’re using a pitcher making his 1st start of the year doesn’t scare me away. St. Louis is 3-5 against lefties as well.

Take the RED SOX -1.5 (+150).

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Over/Under

It’s slated to be 77 degrees with an 8-mph wind blowing out to right-center. The Over is 5-0 in the Cardinals’ last 5 following a loss and in their last 5 interleague games. The Over is 4-0 in the Red Sox’s last 4 home games and home games against a righty.

Take the OVER 11 (-105).

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