Arizona Diamondbacks at Chicago Cubs odds, picks and predictions

Analyzing Sunday’s Arizona Diamondbacks at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (75-68) and Chicago Cubs (76-67) meet for the finale of a 4-game series Sunday. First pitch from Wrigley Field is set for 2:20 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Diamondbacks vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Diamondbacks lead 3-0

Arizona won 3-2 as a +125 road underdog in the 10th inning on Saturday for its 3rd straight win in the series. The D-backs scored twice in the 10th, first on a wild pitch then on an RBI single from RF Tommy Pham.

Arizona has won 4 straight and is 6-4 in its last 10 and 37-33 on the road. Chicago fell to 40-34 at home with its 3rd straight loss. The Cubs are 5-5 in their last 10 games.

Diamondbacks at Cubs projected starters

RHP Brandon Pfaadt vs. RHP Kyle Hendricks

Pfaadt (1-8, 6.27 ERA) makes his 16th start. The rookie has a 1.46 WHIP, 2.9 BB/9 and 8.2 K/9 in 74 2/3 innings.

  • Last start: Loss, 3 2/3 IP, 3 ER, 6 H, 2 BB, 4 K in a 3-2 home loss Tuesday vs. the Colorado Rockies
  • First career start vs. Chicago

Hendricks (5-7, 3.73 ERA) makes his 21st start. He has a 1.14 WHIP, 1.2 BB/9 and 6.2 K/9 in 115 2/3 innings.

  • Last start: No-decision, 5 1/3 IP, 4 ER, 7 H, 0 BB, 5 K in an 11-8 home win Tuesday vs. San Francisco Giants
  • Career vs. Arizona: 4-3, 3.83 ERA (54 IP, 23 ER), 1.20 WHIP, 8 K/9 in 9 starts

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Diamondbacks at Cubs odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:58 a.m. ET.

  • Moneyline (ML): Diamondbacks +128 (bet $100 to win $128) | Cubs -152 (bet $152 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-160) | Cubs -1.5 (+132)
  • Over/Under (O/U): 9 (O: +100 | U: -122)

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Diamondbacks at Cubs picks and predictions

Prediction

Diamondbacks 5, Cubs 3

Moneyline

LEAN DIAMONDBACKS (+128).

While these are 2 evenly-matched teams, the Diamondbacks have been dominant over the Cubs in recent matchups. Arizona is 3-0 vs. Chicago in this series and 6-1 in the last 7 meetings with Chicago. The Diamondbacks are also the hotter team as they are 5-1 in their last 6 overall.

This is only a lean because the Cubs are at home and they are 2-1 in Hendricks’ last 3 starts vs. Arizona.

Run line/Against the spread

PASS.

I’m a fan of the Diamondbacks to cover, but not at this price. Bet on the moneyline and/or total instead.

Over/Under

BET UNDER 9 (-122).

The Under has hit in all 3 games of this series and is also 7-3 in the last 10 Arizona-Chicago matchups overall. For Arizona the Under is 7-3 in its last 10 overall and for Chicago the Under is 8-2 in its last 10.

The Under is also 4-1 in Hendricks’ last 5 starts overall and 2-1 in his last 3 starts vs. Arizona. The Under is 3-1-1 in Pfaadt’s last 5 starts.

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Arizona Diamondbacks and Chicago Cubs odds, picks and predictions

Analyzing Friday’s Arizona Diamondbacks at Chicago Cubs odds and lines, with MLB expert picks and predictions.

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The Arizona Diamondbacks (73-68) and Chicago Cubs (76-65) meet Friday as they continue a 4-game series. First pitch at Wrigley Field is slated for 2:20 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Arizona leads 1-0

Arizona hit 3 home runs en route to a 6-2 triumph in Thursday’s series lid-lifter. The win snapped a 3-game road losing streak for the Diamondbacks. Arizona is 3-1 over its last 4 games and holds the final NL Wild Card.

Chicago had a 4-game win streak snapped in Thursday’s loss. A club that had banged out 50 hits during the win streak collected just 5 while facing 6 different Arizona hurlers.

Diamondbacks at Cubs projected starters

RHP Zac Gallen vs. RHP Jameson Taillon

Gallen (14-7, 3.48 ERA) makes his 30th start of the season. He has a 1.11 WHIP, 1.9 BB/9 and 9.4 K/9 through 178 2/3 IP.

  • Last start: Loss, 5 1/3 IP, 5  ER, 8 H, 1 BB, 4 K in 8-5 home loss vs. Baltimore Orioles Sunday
  • 2023 road stats: 3-5, 4-81 ERA in 88 2/3 IP in 15 starts
  • Career starts vs. Cubs: 1-1, 4.35 ERA in 20 2/3 IP across 4 starts
  • Has allowed 11 ER over his last 10 2/3 IP

Taillon (7-9, 5.51 ERA) is tabbed for his 26th start of the season. He has a 1.34 WHIP, 2.3 BB/9 and 8.0 K/9 through 127 1/3 IP.

  • Last start: No-decision, 5 2/3 IP, 7 H, 5 R, 0 BB, 7 K in 15-7 win at Cincinnati Reds Sunday
  • 2023 home stats: 3-6, 5.86 ERA in 66 IP in 13 starts
  • Career starts vs. Diamondbacks: 1-1, 5.25 ERA in 12 IP across 2 starts
  • Has allowed 4-plus runs in 5 straight starts, and 4 or more earned runs in 3 those outings
  • Season ERA is a would-be career-high

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Diamondbacks at Cubs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:45 a.m. ET.

  • Moneyline: Diamondbacks -115 (bet $115 to win $100) | Cubs -105 (bet $105 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks -1.5 (+155) | Cubs +1.5 (-190)
  • Over/Under (O/U): 7 (O: -120 | U: +100)

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Diamondbacks at Cubs picks and predictions

Prediction

Cubs 4, Diamondbacks 3

Moneyline

The Chicago Cubs have hit the Moneyline in 18 of their last 25 games at home (+8.80 Units, 25% ROI).

Arizona is just 9-19 on the road in the 2nd half. Chicago has been bashing right-handed pitching of late (.825 OPS in 2nd half), and Taillon’s home numbers are sullied by a .365 batting average on balls in play. He’s a fly-baller helped by a breeze favoring pitchers in the forecast.

Leveraging FanDuel Sportsbook for the best odds here, BET THE CUBS (+102).

Run line/Against the spread

The Cubs’ end of this action is drowning in juice. PASS.

Over/Under

There is some Under shading to the prognostication for this one, but the public is all over it. Keep an eye on FanDuel’s O/U if a 7.5 stays listed and gets to -115, that mix would have some minimal value. Otherwise, PASS.

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Arizona Diamondbacks and Chicago Cubs odds, picks and predictions

Analyzing Thursday’s Arizona Diamondbacks at Chicago Cubs odds and lines, with MLB expert picks and predictions.

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The Arizona Diamondbacks (72-68) and Chicago Cubs (76-64) meet Thursday as they open a 4-game series. First pitch at Wrigley Field is slated for 7:40 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Arizona won the 2022 series 4-3.

Arizona is looking to snap a 3-game road losing streak and are just 8-18 over their last 26 away games.

The Cubs have surged in the standings in the 2nd half. Since July 14, Chicago has played .667 ball (34-17). Over that span, the Cubs have gained 5 1/2 games in the NL Central standings. They enter Thursday 1 1/2 games behind the 1st-place Milwaukee Brewers and 2nd in the Wild Card race.

Diamondbacks at Cubs projected starters

RHP Ryne Nelson vs. RHP Javier Assad

Nelson (6-7, 5.47 ERA) is tabbed for his 26th start. He has logged a 1.46 WHIP, 2.7 BB/9 and 5.9 K/9 in 125 innings.

  • Last start: Loss, 3 IP, 7 H, 6 R, 1 BB, 2 K in 10-5 home loss vs. San Diego Padres on Aug. 11
  • 2023 road stats: 4-2, 3.30 ERA in 73 2/3 IP in 13 starts
  • Owns a 7.60 ERA over his last 7 starts
  • Being recalled from Triple-A Reno for this start

Assad (3-2, 2.69 ERA) makes his 26th appearance and 8th start. He has registered a 1.18 WHIP, 3.4 BB/9 and 6.9 K/9 in 87 innings.

  • Last start: No-decision, 8 IP, 7 H, 0 R, 1 BB, 7 K in 2-1 loss at Cincinnati Reds Saturday withseason-high 98 pitches
  • 2023 home stats: 0-2, 3.55 ERA in 45 2/3 IP in 15 games (3 starts)
  • Has never faced Arizona as a starter
  • Has allowed just 8 ER over his last 48 1/3 IP (1.49 ERA), which includes time in the Chicago bullpen

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Diamondbacks at Cubs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:54 p.m. ET.

  • Moneyline: Diamondbacks +135 (bet $100 to win $135) | Cubs -160 (bet $160 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-145) | Cubs -1.5 (+120)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

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Diamondbacks at Cubs picks and predictions

Prediction

Cubs 6, Diamondbacks 5

Moneyline

The Cubs have been a good wagering play for much of the 2nd half. That time to shine — a period of undervalued profitability — may be nearing an end, and Assad figures as overvalued.

PASS.

Run line/Against the spread

Same as above: no interest in trying to get the Cubs by unless the plus money comes back at +130 or better. PASS.

Over/Under

Cooler temps and an inward breeze are expected  for this game, but Chicago has been mashing right-handers lately (.835 OPS in the 2nd half), and Nelson is a question mark/negative lean in his return from stint in minors.

Assad has benefited from a .255 batting average on balls in play and an 84.1% left-on-base rate. Look for Cubs pitching to be trying to put a high-scoring game in the barn late.

BACK THE OVER 8.5 (-110).

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Arizona Diamondbacks at Chicago Cubs odds, picks and predictions

Analyzing Thursday’s Arizona Diamondbacks at Chicago Cubs odds and lines, with MLB expert picks and predictions.

The Arizona Diamondbacks (18-21) open a 4-game road series against the Chicago Cubs (15-21) Thursday. First pitch is 7:40 p.m. ET at Wrigley Field. Let’s analyze Tipico Sportsbook‘s lines around the Diamondbacks vs. Cubs odds with MLB picks and predictions.

The Cubs lead the season series 2-1.

The Diamondbacks have lost 6 games in a row. Their last win was at home over the Cubs in the season-series opener Friday.

The Cubs lost 3-2 to the Pittsburgh Pirates Wednesday. That snapped a 4-game win streak that started against the Diamondbacks last weekend.

Diamondbacks at Cubs projected starters

RHP Zac Gallen vs. RHP Marcus Stroman

Gallen (2-0, 1.05 ERA) makes his 7th start. He has a 0.67 WHIP, 1.3 BB/9 and 9.2 K/9 through 34 1/3 IP.

  • Has pitched 6 innings or more in his last 4 starts.
  • Had a no-decision in a 4-2 loss against the Cubs Saturday in his last start where he allowed 1 run on 2 hits with 9 strikeouts over 6 innings.
  • Has not allowed more than 2 earned runs in any start and has not given up any runs in 3 of them.

Stroman (1-3, 5.13 ERA) makes his 6th start. He has a 1.18 WHIP, 2.4 BB/9 and 7.5 K/9 through 26 1/3 IP.

  • Picked up his first win of the year in his last start with 7 scoreless innings, 2 hits,1 walk and 5 strikeouts at the Milwaukee Brewers Saturday.
  • The Cubs are 1-4 through his first 5 outings.

Diamondbacks at Cubs odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:05 a.m. ET.

  • Money line (ML): Diamondbacks -112 (bet $112 to win $100) | Cubs -108 (bet $108 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks -1.5 (+145) | Cubs +1.5 (-180)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

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Diamondbacks at Cubs picks and predictions

Prediction

Diamondbacks 3, Cubs 2

Money line

Only 2 teams have fewer home wins this season than the Cubs’ 6 and that is even after winning 2 of 3 games against the Pirates.

Stroman’s allowed 8 runs (7 earned) in 4 1/3 innings April 20 against the Tampa Bay Rays in his last home start, while Gallen has a 1.74 ERA in his first 2 road starts of the season.

The Diamondbacks are starting to look again like the team most expected them to be, but with Gallen on the mound, I like them.

Take the DIAMONDBACKS (-112).

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Run line/Against the spread

This is only the 8th time all season the Diamondbacks have been favored on the run line. They are 2-5 ATS in those games thus far this season.

The Cubs are 20-16 ATS overall this season and 17-10 ATS as the underdog.

The Diamondbacks have eight 1-run wins in their 18 victories and 2 of their 4 wins when Gallen pitches are 1-run victories, which makes it hard to trust them to cover. I like the price for the Diamondbacks but don’t trust them to win by margin.

However, it is almost not worth a wager on the Cubs +1.5 (-180) because of the hefty tag. PASS, unless you are going to include a Cubs +1.5 (-180) wager in a parlay bet.

Over/Under

Only 2 of Gallen’s 6 starts have had more than 8 runs.

In the most recent series between the Cubs and Dbacks, no game had more than 7 runs.

Stroman’s last 2 starts have had fewer than 9 runs.

Take UNDER 8.5 (-110).

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Arizona Diamondbacks at Chicago Cubs odds, picks and prediction

Analyzing Sunday’s Arizona Diamondbacks at Chicago Cubs odds and lines, with MLB picks and predictions.

The Arizona Diamondbacks (31-69) and Chicago Cubs (48-51) play the finale of their three-game series Sunday. It is the rubber match of this series after the Cubs won the opener and the Diamondbacks won the second game. First pitch for Sunday’s game is at 2:20 p.m. ET at Wrigley Field. Let’s analyze BetMGM Sportsbook‘s lines around the Diamondbacks vs. Cubs odds with MLB picks and predictions.

LHP Caleb Smith is the projected starting pitcher for the Diamondbacks. He is 3-6 with a 4.38 ERA, 1.35 WHIP, 10.2 K/9 and 4.5 BB/9 through 78 IP spanning 10 starts and 18 relief appearances starts.

He is 0-4 in his four road starts this season. Arizona is 2-8 when he starts and, before winning his last start against the Pittsburgh Pirates, lost seven consecutive Smith starts.

RHP Trevor Williams is the projected starting pitcher for the Cubs. He is 3-2 with a 5.68 ERA, 1.62 WHIP, 9.5 K/9 and 3.8 BB/9 across 52 1/3 IP over 11 starts and one appearance out of the bullpen.

The Cubs won all five of his starts at Wrigley Field. He pitches much better at home with an ERA of 3.81 compared to a 7.88 mark on the road.

MLB betting offers/promotions

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Diamondbacks at Cubs odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 11:15 a.m. ET.

  • Money line: Diamondbacks +150 (bet $100 to win $150) | Cubs -185 (bet $185 to win $100)
  • Against the spread/ATS: Diamondbacks +1.5 (-130) | Cubs -1.5 (+105)
  • Over/Under: 9 (O: -105 | U: -115)

Prediction

Cubs 7, Diamondbacks 3

Money line (ML)

The Diamondbacks have surprised recently with five wins in their last six games, including a 7-3 win over the Cubs Saturday. Their 12-39 road record is still the second-worst in baseball, but they’re 2-3 in their last five away from home; however, Smith took the loss in all four of his road starts this season.

Meanwhile, the Cubs are 29-18 at home and have alternated winning and losing in their last six games at the “friendly confines.” Having lost Saturday, they are in line for a win in the series finale, especially considering they have not yet lost with Williams starting at home.

Take the CUBS (-185).

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Run line/Against the spread (ATS)

With their win and cover Saturday afternoon, the Diamondbacks improved their road record against the spread to 21-30 ATS but only two teams have worse ATS records on the road. Of the eight losses the Diamondbacks have in Smith’s starts this season, five were by at least 2 runs.

The Cubs are 25-22 ATS at home this season and three of their five wins in Williams’ home starts were by at least 2 runs. Their loss to Arizona Saturday was their first ATS loss in five games.

Take the CUBS -1.5 (+105).

Over/Under (O/U)

So far in the series, both games have gone for totals of 10 and 10.5 runs.

Five of the Diamondbacks’ last six games had a total of 10 or more runs and four of the last six for the Cubs finished with totals of 10 or more runs.

Take OVER 9 (-105).

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Arizona Diamondbacks at Chicago Cubs odds, picks and prediction

Analyzing Saturday’s Arizona Diamondbacks at Chicago Cubs odds and lines, with MLB picks and predictions.

The Arizona Diamondbacks (30-69) seek to bounce back from an 8-3 loss in the series opener against the Chicago Cubs (48-50) as the two teams clash again Saturday afternoon. First pitch is scheduled for 2:20 p.m. ET at Wrigley Field. Let’s analyze BetMGM Sportsbook‘s lines around the Diamondbacks vs. Cubs odds with MLB picks and predictions.

RHP Merrill Kelly is the projected starting pitcher for the Diamondbacks. He is 6-7 with a 4.46 ERA, 1.22 WHIP, 7.6 K/9 and 2.1 BB/9 over 117 IP spanning 20 starts.

He has been the Diamondbacks’ best pitcher over the last month. He has won four straight decisions and the team has won five of his last six starts.

RHP Alec Mills is the projected starting pitcher for the Cubs. He is 4-3 with a 4.64 ERA, 1.43 WHIP, 7.9 K/9 and 3.1 BB/9 through 52 1/3 IP over seven starts and 12 relief appearances.

He has started only two games at home this season but won them both and has a home ERA of 2.86 over 22 total innings.

MLB betting offers/promotions

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Diamondbacks at Cubs odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 11:40 a.m. ET.

  • Money line: Diamondbacks +140 (bet $100 to win $140) | Cubs -165 (bet $165 to win $100)
  • Against the spread/ATS: Diamondbacks +1.5 (-125) | Cubs -1.5 (+105)
  • Over/Under: 11 (O: -105 | U: -115)

Prediction

Cubs 5, Diamondbacks 3

Money line (ML)

The Cubs took the series opener 8-3 and are now 29-17 at home. Mills is undefeated in two home starts this season.

The Diamondbacks are 11-39 on the road and have won only one of Kelly’s last five road starts.

Take the CUBS (-165).

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Run line/Against the spread (ATS)

The Diamondbacks are 47-52 ATS in 2021 and 20-30 ATS on the road. In their last 32 road games, they have lost 30 times and 24 of those losses were by 2 or more runs.

The Cubs are 25-21 ATS at home and their last nine home wins were each by at least 2 runs.

Take the CUBS -1.5 (+105).

Over/Under (O/U)

Friday’s game went Over the projected 10-run total but less than half the games at Wrigley Field have hit the Over this year.

None of Kelly’s last six starts went Over 11 runs and none of Mills’ seven starts went Over 11 runs.

That would suggest that the most you can expect, based on trends, is a push.

Take UNDER 11 (-115).

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Arizona Diamondbacks at Chicago Cubs odds, picks and prediction

Analyzing Friday’s Arizona Diamondbacks at Chicago Cubs odds and lines, with MLB picks and predictions.

The Arizona Diamondbacks (30-68) open a five-game road trip with the first of three games against the Chicago Cubs (47-50) Friday afternoon. First pitch is at 2:20 p.m. ET at Wrigley Field. Let’s analyze BetMGM Sportsbook‘s lines around the Diamondbacks vs. Cubs odds with MLB picks and predictions.

RHP Zac Gallen is the projected starting pitcher for the Diamondbacks. He is 1-4 with a 3.86 ERA, 1.33 WHIP, 10.8 K/9 and 4.4 BB/9 in 46 2/3 IP over 10 starts.

His last start came against the Cubs in Phoenix Saturday in his first start off the injured list. He went 5 2/3 innings and allowed only one run on three hits but ended up with a no-decision as the Diamondbacks bullpen yielded three ninth-inning runs in a 4-2 defeat.

RHP Zach Davies is the projected starting pitcher for the Cubs. He is 5-6 with a 4.35 ERA, 1.48 WHIP, 5.7 K/9 and 4.8 BB/9 in 97 1/3 IP over 20 starts.

His last start came against the Diamondbacks Sunday in a 6-4 loss. He got a no-decision in the start, giving up two runs, six hits and four walks in 4 2/3 innings. The Cubs have lost his last four starts.

MLB betting offers/promotions

BetMGM Sportsbook offers available in CO, IA, IN, MI, NJ, PA, TN, VA, WV and Washington D.C. New customer offers, terms and conditions apply.

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Diamondbacks at Cubs odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 9:35 a.m. ET.

  • Money line: Diamondbacks +115 (bet $100 to win $115) | Cubs -140 (bet $140 to win $100)
  • Against the spread/ATS: Diamondbacks +1.5 (-160) | Cubs -1.5 (+135)
  • Over/Under: 10 (O: -115 | U: -105)

Prediction

Diamondbacks 5, Cubs 4

Money line (ML)

The Diamondbacks are riding a four-game winning streak that started in the final game in their series at home against the Cubs. They are the league’s second-worst road team this season at 11-38.

The Cubs are 28-17 at home, but they lost four of six games in their last homestand. They have lost Davies’ last four starts and have not won at home with him on the mound since June 13.

Mainly because of the pitching matchup, if the Diamondbacks are going to win any of the games in the series, it is this one.

Take the DIAMONDBACKS (+115).

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Run line/Against the spread (ATS)

Arizona’s road record against the spread is not nearly as bad as its actual record. It is 20-29 ATS on the road this season.

The Cubs are tied for the third-highest ATS cover percentage in baseball at 55.7%. They are 24-21 ATS at Wrigley. They failed to cover the spread in four of their last six home games but have covered the spread in their last three games overall.

Expecting Arizona to sneak an outright upset win, you have to like them against the spread as well. Take the DIAMONDBACKS +1.5 (-160).

Over/Under (O/U)

Less than half (46.5%) of the games at Wrigley Field have gone Over the projected total in 2021.

Arizona scored an average of 3.71 runs per road game. Their road ERA is 5.55.

Only two of the Cubs’ last seven games has had a total of 11 runs or more. The Diamondbacks have had five of their last nine road games end up with totals of 11 or more runs.

Gallen will quiet the Cubs’ bats and the Diamondbacks aren’t going to score enough to get the total into double digits.

Take UNDER 10 (-105).

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Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.

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