Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Sunday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (44-45) and San Diego Padres (49-44) close out a 3-game series Sunday. First pitch from Petco Park is at 4:10 p.m. ET (Roku). Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 5-4

The Diamondbacks, after losing Friday’s opener on a walk-off homer, scored 3 runs in the 10th inning to win 7-5 Saturday and even the series. They are 5-2 in their last 7 games.

Saturday’s loss for the Padres was just their 4th in their last 16 games overall and their 2nd in their last 11 at home.

Diamondbacks at Padres projected starters

RHP Ryne Nelson vs. RHP Dylan Cease

Nelson (5-6, 5.42 ERA) makes his 14th start and 16th appearance. He has a 1.56 WHIP, 2.3 BB/9 and 6.0 K/9 in 73 innings.

  • Last start: No-decision, 5 IP, 1 ER, 6 H, 1 BB, 3 K in 6-5 road loss to Los Angeles Dodgers Tuesday
  • 2024 vs. Padres: 1-1, 9.72 ERA (8 1/3 IP, 9 ER), 2.28 WHIP, 4.3 K/9 in 2 starts
  • Career vs. Padres: 2-3, 6.95 ERA (33 2/3 IP, 26 ER), 1.57 WHIP, 6.1 K/9 in 7 starts

Cease (7-7, 4.24 ERA) makes his 19th start. He has a 1.12 WHIP, 2.8 BB/9 and 11.5 K/9 in 102 innings.

  • Last start: Loss, 3 2/3 IP, 6 ER, 8 H, 2 BB, 5 K in 7-0 road loss to Texas Rangers Tuesday
  • Has allowed 4+ runs 6 times this season, 3 times in his last 4 outings
  • 2024 vs. Diamondbacks: 1-0, 1.35 ERA (6 2/3 IP, 1 ER), 3 H, 0 BB, 8 K in 1 start, a 7-1 road win May 3
  • Career vs. Diamondbacks: 1-0, 1.84 ERA (14 2/3 IP, 3 ER), 0.41 WHIP, 9.8 K/9 in 2 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Diamondbacks at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:36 a.m. ET.

  • Moneyline (ML): Diamondbacks +135 (bet $100 to win $135) | Padres -160 (bet $160 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-150) | Padres -1.5 (+125)
  • Over/Under (O/U): 8 (O: -120 | U: +100)

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Diamondbacks at Padres picks and predictions

Prediction

Padres 8, Diamondbacks 6

Moneyline

The Diamondbacks are 2 walk-off hits from a 7-game winning streak. They have scored 7 runs or more in 4 straight games.

But Nelson has struggled against the Padres (-160) this season and Cease’s 1 start against Arizona was a good one.

Arizona is 22-24 on the road this season and 17-25 against teams with winning records, so expect the Padres to bounce back and win the finale and the series, but there are plus odds on the run line to bet.

PASS.

Run line/Against the spread

All 5 of the Padres’ wins over the Diamondbacks have been by 2 or more runs. Nine of their last 10 wins have been by 2 or more runs. Nine of their 10 wins with Cease starting have been by at least 2 runs.

Twelve of Arizona’s last 13 losses have been by multiple runs.

BET PADRES -1.5 (+125).

Over/Under

Eight of the 9 games this season between Arizona and San Diego have had more than 8 total runs.

Three of Cease’s last 4 starts have had more than 8 total runs.

The Diamondbacks’ last 5 games, and 9 of their last 11, have had more than 8 total runs.

BET OVER 8 (-120).

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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Saturday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (43-45) and San Diego Padres (49-43) face off Saturday for the 2nd game of their 3-game series. First pitch from PETCO Park is at 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 5-3.

The Diamondbacks lost the opener Friday 10-8 on a walk-off home run by 3B Manny Machado after they scored 6 in the top of the 9th to take a 8-7 lead. The Over (8.5) cashed in. The D-Backs have still won 4 of 6.

The Padres’ win gave them 3 straight. They are 12-3 in their last 15 games after losing 5 in a row.

Diamondbacks at Padres projected starters

RHP Brandon Pfaadt vs. RHP Matt Waldron

Pfaadt (3-6, 4.28 ERA) makes his 18th start. He has a 1.18 WHIP, 2.3 BB/9 and 8.2 K/9 through 103 innings.

  • Last start: No-decision, 6 IP, 1 ER, 5 H, 2 BB, 8 K in 5-1 home win over Oakland A’s Sunday
  • 0-2 with 6.35 ERA in 2 starts vs. Padres this year

Waldron (5-7, 3.56 ERA) makes his 18th start. He has a 1.19 WHIP, 2.7 BB/9 and 8.4 K/9 through 93 2/3 innings.

  • Last start: Loss, 4 1/3 IP, 4 R (3 ER), 6 H, 1 BB, 3 K in 4-1 road loss to Boston Red Sox on Sunday
  • Got the win in a 13-1 victory June 8 over Arizona, allowing 1 run in 6 innings
  • 1-2 with 8.36 ERA in 3 career starts vs. Arizona

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Diamondbacks at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11 a.m. ET.

  • Moneyline (ML): Diamondbacks +100 (bet $100 to win $100) | Padres -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-225) | Padres -1.5 (+165)
  • Over/Under (O/U): 7.5 (O: +100 | U: -120)

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Diamondbacks at Padres picks and predictions

Prediction

Diamondbacks 7, Padres 6

Moneyline

The Diamondbacks are 2 walk-off hits from a 6-game winning streak. They scored 6 in the 9th inning to take a 1-run lead, only to have closer Paul Sewald give up 2 homers in the bottom of the inning. They have scored 29 runs in their last 3 games.

The Padres are 12-3 in their last 15 games and 10-1 in their last 11 home games.

Waldron picked up his 1st career win over Arizona last month, but he has struggled in 2 other career starts, while Pfaadt has struggled against the Padres this season.

The bats will be active.

BET DIAMONDBACKS (+100). 

Run line/Against the spread

Of the last 18 times the Diamondbacks have covered the spread, 17 have been outright wins.

Of the last 8 times that the Padres failed to cover the spread, 7 were outright losses.

And at -225 odds, you are far better taking the even-money odds for an Arizona outright win than the cover.

PASS. 

Over/Under

Six of the last 7 meetings this season have had double-digit runs.

The Diamondbacks have scored 5 or more runs in 5 straight games. Eight of their last 10 games have had more than 7 total runs.

BET OVER 7.5 (+100). 

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Friday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Arizona Diamondbacks (43-44) open a 3-game road series against the San Diego Padres (48-43) Friday. First pitch from Petco Park is at 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 4-3

The Diamondbacks are coming off a series win on the road over the Los Angeles Dodgers. They won the finale 9-3 Thursday behind 1B Christian Walker‘s 2 homers and a 4-run 9th inning to blow the game open. They have won 4 of their last 5 games.

The Padres are 11-3 since losing 5 straight games June 14-18. They went 4-2 on their 6-game road trip and won the final 2 games of a series against the Texas Rangers, beating them 3-1 Thursday.

Diamondbacks at Padres projected starters

RHP Slade Cecconi vs. RHP Randy Vasquez

Cecconi (2-6, 5.81 ERA) makes his 12th start and 13th appearance. The rookie has a 1.26 WHIP, 1.7 BB/9 and 7.5 K/9 in 57 1/3 innings.

  • Last start: No-decision, 4 IP, 3 ER, 5 H, 2 BB, 7 K in 9-4 home loss to Oakland A’s June 28
  • 2024 vs. Padres: 0-1, 9.35 ERA (8 2/3 IP, 9 ER), 1.73 WHIP, 7.3 K/9 in 2 starts
  • Career vs. Padres: 0-1, 7.84 ERA (10 1/3 IP, 9 ER), 1.55 WHIP, 7.0 K/9 in 3 appearances (2 starts)

Vasquez (2-4, 4.88 ERA) makes his 12th start. The rookie has a 1.67 WHIP, 2.3 BB/9 and 5.6 K/9 in 51 2/3 innings.

  • Last start: No-decision, 4 IP, 1 ER, 5 H, 1 BB, 1 K in 9-2 road win over Boston Red Sox June 28
  • Went 2-1 with 4.20 ERA in 6 June starts
  • 2024 vs. Diamondbacks: 0-0, 4.05 ERA (6 2/3 IP, 3 ER), 6 H, 0 BB, 3 K in 1 start, a 4-3 home loss June 6
  • Career vs. Diamondbacks: 0-0, 5.00 ERA (9 IP, 5 ER), 1.22 WHIP, 5.0 K/9 in 2 appearances (1 start)

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Diamondbacks at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:17 p.m. ET.

  • Moneyline (ML): Diamondbacks -115 (bet $115 to win $105) | Padres -105 (bet $105 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks -1.5 (+145) | Padres +1.5 (-175)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

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Diamondbacks at Padres picks and predictions

Prediction

Padres 6, Diamondbacks 4

Moneyline

The Diamondbacks have lost their last 2 series openers. They are 21-23 on the road this season.

The PADRES (-105) are 24-22 at home this season but are 9-1 in their last 10 games at Petco Park. They have won 3 of the last 4 starts for Vasquez.

The Diamondbacks are 1-3 in Cecconi’s last 4 outings.

BET PADRES (-105).

Run line/Against the spread

The last 10 times the Padres covered the spread, they won the game outright.

So at -175 odds for them to cover the +1.5, you’re better off going with the moneyline.

PASS.

Over/Under

Five of the 7 games between the teams this season have had double-digit runs, including 3 of the 4 in San Diego June 6-9.

Vasquez’s last 3 starts and 4 of his last 6 have had totals of 10 or more.

The Diamondbacks have scored 5 or more runs in 4 straight games and 21 runs in the last 2 games alone.

Nine of the Padres’ last 10 wins have had more than 8 total runs.

BET OVER 8.5 (-110).

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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Monday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

The Arizona Diamondbacks (2-2) visit the San Diego Padres (2-2) Monday with the 1st pitch at 9:40 p.m. ET at Petco Park.  Let’s analyze BetMGM Sportsbook’s lines around the Diamondbacks vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Padres won 2022 season series 14-5

The Diamondbacks split a 4-game series at the Los Angeles Dodgers to start the season, winning 2-1 on Sunday. A 2-out, 9th-inning bunt single by OF Jake McCarthy drove in the winning run. Starter Zach Davies pitched 5 strong innings, allowing 1 ER, 4H, 2 BBs and 4 K’s.

The Padres split their opening series against the Colorado Rockies, winning the final 2 games. On Sunday, a 3-run HR by SS Xander Bogaerts in the 2nd inning was enough offense in a 3-1 win. Starter Seth Lugo went 7 innings and allowed only 1 run on 4 hits.

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Diamondbacks at Padres projected starters

RHP Ryne Nelson vs. LHP Ryan Weathers

Nelson was 1-1 with 1.47 ERA in 2022. He had a 0.82 WHIP, 2.9 BB/9 and 7.9 K/9 in 18 1/3 IP last season.

  • 2 of 3 starts as rookie were against Padres
  • 1-1 with 2.19 ERA against Padres in 12 1/3 IP

Weather was 0-0 with a  9.82 ERA in 2022. He had a 2.73 WHIP, 4 BB and 3 K through 3 2/3 IP.

  • Had 4.91 ERA in 5 spring training appearences
  • Is 0-1 with 6.75 ERA vs. Arizona in 4 appearances (2 starts)

Diamondbacks at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:41 a.m. ET.

  • Moneyline (ML): Diamondbacks +115 (bet $100 to win $115) | Padres -140 (bet $140 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-175) | Padres -1.5 (+145)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Diamondbacks at Padres picks and predictions

Prediction

Padres 4, Diamondbacks 3

Moneyline

The Diamondbacks were 2-7 in San Diego last season and 5-14 against the Padres overall.

Both teams will have their 5th starter on the mound so expect the bullpens to factor in early. San Diego’s bullpen only worked 2 innings in their win on Sunday, while Arizona’s pitched 4 innings and has gone 14 innings through 4 games.

The rested Padres relievers will be the difference.

BET PADRES (-140).

Run line/Against the spread

The Padres’ 2 wins were both by at least 2 runs while Arizona’s 2 losses have both been by at least 6 runs.

The Padres had baseball’s 2nd-worst home ATS record last season at 32-53 ATS.

Betting the Diamondbacks to cover isn’t as good a value at -175 as the Padres on the moneyline at -140, so PASS on this bet.

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Over/Under

Both teams have had 2 games of more than 8 runs and 2 of fewer than 8. Ten of their 19 games last season had fewer than 8 total runs.

BET UNDER 8 (-105).

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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Wednesday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks and predictions.

The Arizona Diamondbacks (65-70) close out their 3-game road series against the San Diego Padres (75-62) Wednesday. First pitch at Petco Park is 8:40 p.m. ET (FS1). Let’s analyze Tipico Sportsbook‘s lines around the Diamondbacks vs. Padres odds with MLB picks and predictions.

Season series: Padres lead 10-4 after splitting the first 2 games of series

The Diamondbacks’ bullpen blew another save Tuesday night as Ian Kennedy allowed 2 runs in the bottom of the 9th for a 6-5 loss. It was his 6th blown save the team’s 21st of the season. The loss was just their 3rd in their last 12 games.

The Padres snapped a 3-game losing streak with the win. They have 7 wins in their last 11 games and maintain a 3-game lead for the final NL wild-card berth.

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Diamondbacks at Padres projected starters

LHP Tommy Henry vs. RHP Yu Darvish

Henry (3-3, 4.83 ERA) makes his 7th start. He has a 1.48 WHIP, 4.5 BB/9 and 6.5 K/9 in 31 2/3 IP.

  • Rookie coming off his worst start, allowing 7 R on 8 H in 4 IP of an 18-2 loss to the Philadelphia Phillies Aug. 31
  • In 3 of his 4 starts prior to that outing, he allowed only 1 run.

Darvish (12-7, 3.26 ERA) makes his 26th start. He has a 0.97 WHIP, 1.7 BB/9 and 9.0 K/9 in 162 2/3 IP.

  • Struck out 9 and allowed only 2 H in 7 scoreless IP against the Los Angeles Dodgers in his last start Friday
  • Is 2-0 with 1.80 ERA in 3 starts against Arizona this season

Diamondbacks at Padres odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:09 a.m. ET.

  • Money line (ML): Diamondbacks +175 (bet $100 to win $175) | Padres -220 (bet $220 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-120) | Padres -1.5 (+100)
  • Over/Under (O/U): 7.5 (O: -130 | U: +105)

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Diamondbacks at Padres picks and predictions

Prediction

Padres 6, Diamondbacks 4

Money line

The Padres get to turn to Darvish in the series finale. He has dominated the Diamondbacks in 2022 and has been effective in his career against them.

Henry was knocked around in his last start against the Phillies.

While Arizona has played better recently, the D-backs are 28-36 on the road this season and are 25-40 against teams with winning records.

Their best chance to pick up a series win was Tuesday night with Merrill Kelly starting.

But with the price on Wednesday’s money line for the Padres, PASS and look to the spread and total for your bets.

Run line/Against the spread

The Padres are the league’s worst team at covering the spread at home this season at 21-44 ATS. They have failed to cover the spread in either of the first 2 games of the series.

However, 7 of the Padres’ 10 wins over the Diamondbacks have been by 2 or more runs.

The Diamondbacks are 10-2 ATS in their last 12 games and 80-55 ATS overall this season, but they have had ATS sweeps only 4 times all season and Darvish is one of the less likely pitchers to do it against, based on their performance against him this year.

Take the PADRES -1.5 (+100).

Over/Under

Nine of the 14 game between the 2 teams have had totals of 7 or fewer runs. The Diamondbacks have had totals of 7 or fewer runs in 4 of their last 6 games while 11 of Arizona’s last 16 have had 8 or more runs.

Five of the Padres’ last 6 have had 8 or more runs.

Five of Henry’s 6 starts have had totals of 8 or more runs.

Take OVER 7.5 (-130).

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Arizona Diamondbacks at San Diego Padres odds, picks and predictions

Analyzing Tuesday’s Arizona Diamondbacks at San Diego Padres odds and lines, with MLB expert picks and predictions.

The Arizona Diamondbacks (65-69) face the San Diego Padres (74-62) in the second game of their 3-game road series Tuesday. First pitch from Petco Park is at 9:40 p.m. ET. Let’s analyze Tipico Sportsbook‘s lines around the Diamondbacks vs. Padres odds with MLB picks and predictions.

Season series: Padres lead 9-4

The Diamondbacks shut out the Padres 5-0 in the opener Monday. Rookie RHP Ryne Nelson pitched 7 scoreless innings in his MLB debut to lead the Diamondbacks to their 9th win in their last 11 games.

The Padres have lost 3 straight games but won 6 of the 7 games prior to the skid. They have dominated the Diamondbacks this season, winning 9 of 13 games.

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Diamondbacks at Padres projected starters

RHP Merrill Kelly vs. RHP Joe Musgrove

Kelly (12-5, 2.84 ERA) makes his 28th start. He has a 1.11 WHIP, 2.6 BB/9 and 7.8 K/9 through 164 2/3 IP.

  • Is 1-0 against the Padres in 2022 with a 0.90 ERA over 2 starts.
  • Allowed 2 or fewer runs in 16 starts this season.

Musgrove (9-6, 3.01 ERA) makes his 25th start. He has a 1.04 WHIP, 1.9 BB/9 and 9.0 K/9 through 149 1/3 IP.

  • Recorded a win at Arizona April 9 with 2 ER over 6 IP
  • The Padres are 16-8 in his starts

Diamondbacks at Padres odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:11 a.m. ET.

  • Money line (ML): Diamondbacks +140 (bet $100 to win $140) | Padres -175 (bet $175 to win $100)
  • Run line (RL)/Against the spread (ATS): Diamondbacks +1.5 (-160) | Padres -1.5 (+130)
  • Over/Under (O/U): 7.5 (O: +112 | U: -140)

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Diamondbacks at Padres picks and predictions

Prediction

Diamondbacks 4, Padres 3

Money line

The Diamondbacks have been playing good baseball and have been getting great outings from their starters. Kelly didn’t allow a run in his last start and their starters have not allowed a run in their last 2 games. Arizona is 9-2 in its last 11 games.

The Padres have been consistently good when Musgrove pitches.

In a game where the final outcome could go either way because of good pitching, take the value here. BET the DIAMONDBACKS (+140).

Run line/Against the spread

The Padres have baseball’s worst home ATS record at 21-43 ATS.

The Diamondbacks are 39-24 ATS on the road this season, the 4th-best mark in all of baseball. They are 79-55 ATS overall this season, the 3rd-best mark in the league.

This one is probably the surer bet but pays out less. If you aren’t as confident with the money line, take the DIAMONDBACKS +1.5 (-160).

Over/Under

Nine of the 13 games between these teams have had 7 or fewer total runs.

Four of the Diamondbacks’ last 5 games have had 7 or fewer runs.

Take UNDER 7.5 (-140).

Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO and NJ. Bet now!

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Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).

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