San Francisco Giants at San Diego Padres odds, picks and prediction

Analyzing Monday’s San Francisco Giants at San Diego Padres odds and lines, with MLB picks and predictions.

The San Francisco Giants (1-2) and San Diego Padres (3-1) tangle in a Monday night NL West series opener at Petco Park. First pitch will be at 10:10 p.m. ET. Let’s analyze BetMGM Sportsbook‘s lines around the Giants vs. Padres odds with MLB picks and predictions.

RHP Anthony DeSclafani is the projected starting pitcher for the Giants. Last year for the Cincinnati Reds, the veteran hurler went 1-2 with a 7.22 ERA, 1.69 WHIP, 6.7 K/9, and 4.3 BB/9 in 33 2/3 IP over nine games (seven starts). DeSclafani has allowed a mere .608 OPS in nine career March/April games.

LHP Adrian Morejon is the projected starting pitcher for the Padres. In 2020, Morejon went 2-2 with a 4.66 ERA, 1.24 WHIP, 11.6 K/9, and 1.9 BB/9 in 19 1/3 IP over nine appearances (four starts). The third-year Major Leaguer has big stuff; his ERA in 2020 was inflated by 39% of fly balls allowed leaving the yard. Morejon throws 96, and he induced a 13.0% swinging-strike rate last summer.

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Giants at Padres odds, lines, picks and prediction

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 5:20 p.m. ET.

  • Money line: Giants +125 (bet $100 to win $125) | Padres -150 (bet $150 to win $100)
  • Against the spread/ATS: Giants +1.5 (-150) | Padres -1.5 (+125)
  • Over/Under: 8.5 (O: -105 | U: -115)

Prediction

Padres 4, Giants 3

Money line (ML)

DeSclafani had a solid spring and the Giants are the lean if any price bounce avails itself. The tag here plummeted in the morning.

Take the Giants if you can wait out a +130.

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Run line/Against the spread (ATS)

BACK THE GIANTS +1.5 (-150).

San Francisco figures to be at its best against lefty pitching.

Over/Under (O/U)

The Under 8.5 (-115) is the lean, but on a humid night with an outward breeze and plenty of pitching uncertainly, a PASS is suggested.

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