San Francisco Giants at Milwaukee Brewers odds, picks and predictions

Analyzing Wednesday’s San Francisco Giants at Milwaukee Brewers odds and lines, with MLB expert picks, predictions and best bets.

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The San Francisco Giants (67-66) and Milwaukee Brewers (75-56) play the middle contest of a 3-game set Wednesday at American Family Field. First pitch will be at 8:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Brewers odds and make our expert MLB picks and predictions for the best bets.

Season series: Giants lead 1-0

San Francisco took Tuesday’s series lid-lifter 5-4. The Giants hit 3 home runs and have 9 round-trippers over their last 4 contests.

Milwaukee was denied a 6th straight win at home with Tuesday’s setback. Brewers pitching has clocked a 3.22 ERA while the club has gone 8-4 since Aug. 14.

Giants at Brewers projected starters

LHP Kyle Harrison vs. RHP Freddy Peralta

Harrison (7-5, 4.00 ERA) makes his 23rd start. He has authored a 1.30 WHIP, 2.9 BB/9 and 8.3 K/9 through 117 innings.

  • Last outing: Win, 6 IP, 1 ER, 5 H, 2 BB, 5 K in 5-3 home victory vs. Chicago White Sox Aug. 19
  • 2024 road stats: 3-4, 4.61 ERA (56 2/3 IP, 29 ER), 1.39 WHIP, 7.3 K/9 in 11 starts
  • Has never faced Brewers

Peralta (8-7, 3.86 ERA) is making his 27th start. He has a 1.20 WHIP, 3.4 BB/9 and 10.4 K/9 through 142 1/3 innings.

  • Last outing: No-decision, 5 IP, 0 ER, 3 H, 2 BB, 2 K in 3-0 defeat at St. Louis Cardinals Thursday
  • 2024 home stats: 4-4, 4.30 ERA (73 1/3 IP, 35 ER), 1.16 WHIP, 10.3 K/9 in 13 starts
  • Career vs. Giants: 0-1, 6.75 ERA (5 1/3 IP, 4 ER), 8 H, 5 BB, 10 K in 3 appearances (2 starts), including 0-1 with 15.43 ERA (2 1/3 IP, 4 ER) in 1 start last year
  • Owns 3.26 ERA over his last 12 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Giants at Brewers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:40 a.m. ET.

  • Moneyline: Giants +140 (bet $100 to win $140) | Brewers -165 (bet $165 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-155) | Brewers -1.5 (+125)
  • Over/Under (O/U): 8 (O: -110 | U: -110)

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Giants at Brewers picks and predictions

Prediction

Brewers 5, Giants 4

Moneyline

PASS: look to the run line for better leverage here.

Run line/Against the spread

Looking at recent starts could well lead to some off-the-mark recency bias for both hurlers, giving too much of an edge to Peralta and the Brewers.

Both clubs have played more 1-run games than the league average (36 per Baseball-Reference.com). The Giants have played 40 and the Brewers have played 42.

Milwaukee has slashed a mere .190/.274/.350 (.625 OPS) while averaging just 3.31 runs per game over its last 13 home games.

BACK THE GIANTS +1.5 (-155).

Over/Under

The Over is 35-22-6 in Milwaukee home games.

Tuesday’s game edged on the Over, and the Over is 3-1 across the last 4 series meetings. The upside has also hit in 10 of the Giants’ last 15 games on the road.

The expected-vs.-actual run scoring/prevention numbers for both clubs make for an Over lean here.

Consider a partial-unit play on the OVER 8 (-110).

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