San Diego Padres at San Francisco Giants odds, picks and predictions

Analyzing Tuesday’s San Diego Padres at San Francisco Giants odds and lines, with MLB expert picks and predictions.

The San Diego Padres (71-59) and San Francisco Giants (61-66) meet Tuesday at 9:45 p.m. ET to continue a 3-game series at Oracle Park. Let’s analyze Tipico Sportsbook‘s lines around the Padres vs. Giants odds with MLB picks and predictions.

Season series: San Diego leads 9-5

San Diego has had its share of woes on the road. The Padres are 12-20 away from home since June 17. However, San Diego is 3-1 with an .894 OPS on its current road trip after a 6-5 win over the Giants Monday.

The Giants have lost 5 straight games, and their pitching has been beaten up in the process. San Francisco owns a bloated 6.59 ERA over that span. The Giants have gone 10-15 with a 4.62 ERA in August.

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Padres at Giants projected starters

LHP Blake Snell vs. RHP Logan Webb

Snell (5-7, 4.24 ERA) has made 17 starts this season. He has a 1.34 WHIP, 3.9 BB/9 and 12.0 K/9 through 87 IP.

  • Has been hurt by a .330 batting average on balls in play.
  • Has faced the Giants twice this season and yielded just 2 ER in 11 2/3 IP.
  • Current San Francisco batters own an aggregate .543 OPS against him.

Webb (11-7, 3.33 ERA) owns a 1.19 WHIP, 2.5 BB/9 and 7.3 K/9 through 159 1/3 IP across 26 starts.

  • Allowed 6 runs over 4 2/3 IP at the Detroit Tigers in his last start and has registered a 4.75 ERA in his last 7 outings.
  • Has faced San Diego twice this season and allowed 2 ER in 16 IP.
  • Owns a nifty 2.94 ERA at home over the last 3 seasons (2020-22).

Padres at Giants odds and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:51 p.m. ET.

  • Money line: Padres -125 (bet $125 to win $100) | Giants +102 (bet $100 to win $102)
  • Run line (RL)/Against the spread (ATS): Padres -1.5 (+135) | Giants +1.5 (-170)
  • Over/Under (O/U): 7.5 (O: +100 | U: -125)

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Padres at Giants picks and predictions

Prediction

Padres 4, Giants 3

Money line

Snell has allowed 1 or 0 runs in 5 of his last 7 starts. The San Francisco offense is prone to long batting slumps and may be in one now.

TAKE SAN DIEGO (-125).

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Run line/Against the spread

The Friars have the better bullpen, but the back end of that ‘pen is caution-flag fatigue territory. It’d be wise to AVOID the run line in taking the road favorite with a low total.

Over/Under

Both starters have good numbers against the batters they’ll see tonight. The Under 7.5 is the play … but only up to -120. PASS otherwise.

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