With the victory, the Lady Vols advance to the Sweet 16 for the 35th time in program history.
Tennessee had five players score 10-plus points.
Sara Puckett and Jillian Hollingshead led the Lady Vols with 13 points each.
Rickea Jackson and Jasmine Powell scored 12 points apiece and Jordan Horston finished with 10 points for Tennessee, which extended its advantage to, 50-22, by halftime over the Mid-American Conference Champion Rockets.
Horston totaled eight rebounds and three assists, while Jackson finished with six rebounds and four assists.
Toledo’s Quinesha Lockett had 19 points to lead all scorers.
PHOTOS: Tennessee defeats Toledo in NCAA Tournament
[mm-video type=playlist id=01eqbz9dkec01s6y18 player_id=01eqbvp13nn1gy6hd4 image=]