Jaguars open as 4.5-point favorites vs. Colts in Week 6

The Jaguars are favored to finish a season sweep of the Colts.

The Jacksonville Jaguars and Indianapolis Colts will play for first place in the AFC South when they meet at EverBank Stadium for a Week 6 tilt.

It’s the second matchup for the divisional rivals this season after the Jaguars earned a 31-21 win at Lucas Oil Stadium in Week 1. Since then, the Colts have won three of their last four games, including a 23-16 win against the Tennessee Titans on Sunday.

While Colts quarterback Anthony Richardson suffered an injury that is likely to keep him out for a while, the team has a capable backup in former Jaguars starter Gardner Minshew II. Still, it’s the Jaguars that are favorites after winning back-to-back games in London.

If you’re looking for betting odds on the Jaguars upcoming game against the Colts, we’ve got you covered. The following lines for the spread, money line and over/under are from BetMGM, giving you an idea of how the oddsmakers think the game will go.

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Moneyline (ML)

  • Jaguars -225 (bet $225 to win $100)
  • Colts +180 (bet $100 to win $180)

Against the spread (ATS)

  • Jaguars -4.5 (-115)
  • Colts +4.5 (-105)

Over/Under (O/U)

  • 45.5 (O: -110 | U: -110)

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