Houston Astros at Seattle Mariners odds, picks and predictions

Analyzing Saturday’s Houston Astros vs. Seattle Mariners odds and lines, with expert MLB picks, predictions and best bets.

The Houston Astros (17-15) continue a 3-game series with the Seattle Mariners (15-17) Saturday evening at T-Mobile Park. First pitch is scheduled for 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Astros vs. Mariners odds and make our expert MLB picks and predictions for the best bets.

Season series: Astros lead series 1-0. Astros won the ALDS vs. the Mariners 3-0 last October, and Houston won the regular-season series 12-7.

The Astros won the first meeting of the regular season 6-4 in Friday’s series opener. The Mariners tied the game 4-4 in the bottom of the 8th inning, but Houston’s OF Kyle Tucker swatted a game-winning 2-run homer in the top of the 9th off of RP Matt Brash.

Despite Friday’s win, the Astros have won just 3 times in the previous 7 outings. The Over cashed Friday, too, but the Under is 7-2 across the previous 9 outings.

The loss Friday snapped a 4-game winning streak for the Mariners. The Over and Under has alternated in the previous 6 outings dating back to April 29.

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Astros at Mariners projected starters

RHP J.P. France vs. LHP Marcos Gonzales

France (2-1, 2.33 ERA – Triple-A Sugar Land) makes his major league debut. He has a 1.03 WHIP, 5.1 BB/9 and 12.1 K/9 in 19 1/3 innings at Triple-A.

  • Posted a 20-17 record and 3.73 ERA across 5 seasons in the minors
  • Had a career-best .136 opponent batting average (OBA), lowest in the Pacific Coast League among pitchers with at least 13 IP

Gonzales (2-0, 4.74 ERA) makes his 6th start. He has a 1.46 WHIP, 2.9 BB/9, 6.9 K/9 in 24 2/3 IP innings.

  • Last start: ND, 3 IP, 5 ER, 8 H, 1 BB, 2 K in 10-8 road win vs. Toronto Blue Jays last time out April 30
  • Home splits this season: 0-0, 4.91 ERA (11 IP, 6 ER), .250 opponent batting average (OBA) in 2 starts
  • Went 1-3 with a 3.81 ERA with 6 HR allowed across 26 IP in 4 starts vs. HOU in 2022

Astros at Mariners odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:50 a.m. ET.

  • Moneyline (ML): Astros +100 (bet $100 to win $100) | Mariners -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Astros +1.5 (-200) | Mariners -1.5 (+165)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Astros at Mariners picks and predictions

Prediction

Astros 6, Mariners 4

Moneyline

The ASTROS (+100) are worth backing behind their prospect France in this middle contest of a 3-game set.

Houston has won 23 of the past 30 road games against a left-handed starting pitcher, while going 37-15 in the past 52 games inside the AL West.

While the Mariners have won 4 of the past 5 games overall, Seattle has lost 6 of the past 7 games against winning teams, and 5 straight at home against teams with a winning overall record.

Run line/Against the spread

The Astros +1.5 (-200) will cost you 2 times your potential return, and that’s quite expensive if you’d like a little bit of insurance.

AVOID, and just play Houston straight up for a much better value.

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Over/Under

The OVER 8 (-115) is the lean, but play it lightly.

The Under has hit in 7 of the past 9 games for the Astros, but the Over is 10-2 in the previous 12 against teams with a losing overall record.

The Over is 5-0 in the past 5 home games against a right-handed starting pitcher, while cashing in 5 of the past 7 games at home, too.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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