Giants vs. Bills: Week 6 staff picks and predictions

The Giants Wire staff offer their picks and predictions ahead of a Week 6 game between the New York Giants and Buffalo Bills.

The New York Giants (1-4) will take on the Buffalo Bills (3-2) this Sunday night at Highmark Stadium in their sixth game of the 2023 regular season.

Opening the week, the Giants were 14.5-point road underdogs and that spread has bounced all over since then. As of this writing, it’s back down to +14.5 after briefly ballooning to +16.

How does the Giants Wire staff see this Week 6 battle shaking out? Here’s a look at our picks and score predictions: