First look: Notre Dame at Duke odds and lines

Looking at Saturday’s Notre Dame at Duke college football odds, lines and trends. Here’s what you need to know.

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The Notre Dame Fighting Irish (4-1) travel to meet the Duke Blue Devils (4-0) on Saturday at Wallace Wade Stadium in Durham, N.C. Kickoff is scheduled for 7:30 p.m. ET (ABC). Below, we look at Notre Dame vs. Duke odds from FanDuel Sportsbook. Also see: SportsbookWire’s college football picks and predictions.

The Fighting Irish will be fighting mad after losing a marquee matchup against Ohio State on the final play of regulation. Notre Dame led 14-10 with :03 left in regulation, but the Buckeyes punched in a 1-yard touchdown to stun the Fighting Irish in their place. Notre Dame still covered, and it is 4-1 against the spread (ATS) this season.

The Blue Devils routed the UConn Huskies in East Hartford by a 41-7 score, with the only drama coming for total bettors. Duke led 41-0 with a total of 45.5, but Under bettors saw UConn break the shutout, and flip the total to an Over result, with just 12 ticks remaining in the game. Duke is now 3-0 ATS in 3 games against FBS opponents.

Notre Dame is No. 13 and Duke is No. 16 in the US LBM Coaches Poll powered by USA TODAY Sports.

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Notre Dame at Duke odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday at 12:39 p.m. ET.

  • Moneyline (ML): Notre Dame -205 (bet $205 to win $100) | Duke +168 (bet $100 to win $168)
  • Against the spread (ATS): Notre Dame -5.5 (-110) | Duke +5.5 (-110)
  • Over/Under (O/U): 50.5 (O: -110 | U: -110)

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2023 betting stats

  • ML: Notre Dame 4-1 | Duke 4-0
  • ATS: Notre Dame 4-1 | Duke 3-1
  • O/U: Notre Dame 3-2 | Duke 2-1-1

Notre Dame at Duke head-to-head

The Fighting Irish lead the all-time series 5-2. Notre Dame earned a 27-13 victory in South Bend in the most recent meeting during the COVID season in front of no fans on Sept. 12, 2020. The most recent meeting in front of fans was at Wallace Wade on Nov. 9, 2019, a 38-7 victory by the Fighting Irish.

Duke’s last win in the series was a 38-35 win on Sept. 24, 2016, in South Bend. The teams have split the 2 all-time meetings in Durham, with the Blue Devils last winning 37-13 at home against the Irish back on Dec. 2, 1961.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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