First look: Chicago Bears at San Francisco 49ers odds and lines

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The Chicago Bears (5-6) take on the San Francisco 49ers (5-7) Sunday in Week 14. Kickoff from Levi’s Stadium is set for 4:25 p.m. ET (FOX). Below, we look at Bears vs. 49ers odds from BetMGM Sportsbook’s NFL odds before making our expert NFL picks and predictions later in the week.

The Bears just missed upsetting the 11-1 Detroit Lions Thanksgiving Day. They succumbed by a 23-20 final score but covered as 10-point dogs. The Bears dismissed coach Matt Eberflus as they dropped their sixth game in a row on an important sequence where they could have used a timeout. QB Caleb Williams was impressive, going 20-for-39 for 256 yards, 3 TDs and 0 INTs.

The Niners lost their third straight in a 35-10 defeat in a blizzard at the Buffalo Bills Sunday night. They also lost RB Christian McCaffrey to a potentially season-ending knee injury. RB Jordan Mason stepped up and rushed 13 times for 78 yards. The Niners couldn’t get anything going in the snowy conditions otherwise.

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Bears at 49ers odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of NFL odds. Lines last updated Monday at 10:10 a.m. ET.

Moneyline (ML): Bears +185 (bet $100 to win $185) | 49ers -225 (bet $225 to win $100)
Against the spread (ATS): Bears +5.5 (-110) | 49ers -5.5 (-110)
Over/Under (O/U): 44.5 (O: -105 | U: -115)

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2024 betting stats

ML: Bears 4-8 | 49ers 5-7
ATS: Bears 6-4-2 | 49ers 4-8
O/U: Bears 4-8 | 49ers 6-5-1

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Bears vs. 49ers head-to-head

The Niners lead the all-time series 35-33-1. The teams have traded wins over the last 6 meetings. They haven’t faced off since Sept. 11, 2022, when the Bears prevailed 19-10 at Solider Field. QB Trey Lance was under center and ineffective. He threw for 164 yards for 0 TDs and 1 INT while rushing 13 times for 54 yards.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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