QB Jacoby Brissett vs. Bucs’ pass rush

Even though the Buccaneers are in the same neighborhood as the Colts in terms of sack production (33-32), their front seven is better by just a little bit. Pass rusher Shaquil Barrett is the league leader in sacks with 14.5 and between their trenches is a formidable duo of defensive tackles in Ndamukong Suh and Vita Vea, who anchor their second-best rushing defense.

Quarterback Jacoby Brissett will probably encounter those guys quite a bit on Sunday, and it will determine whether or not he is successful. After having a hot start to this season, the Colts QB1 has slowed down because of a nagging knee injury, his own targets being injured, and at times, spotty play-calling.

For JB7 to return to being the quarterback, that actually led the league in passing touchdowns at one point, he has to quickly find his rhythm, make the right reads, and complete those big throws downfield. If there are any saving graces for Brissett, it’s the Buccaneers’ secondary allowing the second-most passing yards per game (281 YPG) and third-most passing touchdowns (27).