Chicago Cubs at San Francisco Giants odds, picks and predictions

Analyzing Monday’s Chicago Cubs at San Francisco Giants odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago Cubs (37-41) begin a 4-game series against the San Francisco Giants (36-42) Monday at Oracle Park. First pitch is scheduled for 9:45 p.m. ET (ESPN+). Let’s analyze BetMGM Sportsbook’s lines around the Cubs vs. Giants odds and make our expert MLB picks and predictions for the best bets.

Season series: Cubs lead 2-1

The Cubs and Giants are struggling. Both teams lost Sunday continuing their downward trends.

The Giants were held to 2 hits at St. Louis Cardinals Sunday, but at least both hits brought in runs — C Patrick Bailey’s solo homer PH Wilmer Flores’ RBI double. Unfortunately Giants SP Logan Webb gave up 3 runs in the 1st inning and, in the end, the Giants lost 5-3 — as +110 underdogs with the Over (7) cashing.  — as they were swept in 3 by the Cardinals over the weekend and have lost 5 in a row overall.

The Cubs offense also failed to show up Sunday in a 5-2 home loss as -111 favorites vs. the New York Mets — the Under (8.5) hit. After Mets SP Luis Severino pitched 6 shutout innings of 3-hit ball with no walks and 10 K’s. Once he was removed, Cubs 3B Christopher Morel hit a 2-run homer in the bottom of the 7th inning to cut the deficit to 4-2, but the Mets held on for the win and took 2 of 3 at Wrigley over the weekend.

Cubs at Giants projected starters

LHP Justin Steele vs. LHP Erik Miller

Steele (0-3, 3.16 ERA) makes his 11th start. He has a 1.07 WHIP, 2.4 BB/9 and 8.8 K/9 through 57 innings.

  • Last start: No-decision, 6 2/3 IP, 2 ER, 4 H, 2 BB, 8 K in 5-2 home win vs. Giants Tuesday
  • 2024 road splits: 0-1, 2.51 ERA (28 2/3 IP, 8 ER), 0.90 WHIP, 9.1 K/9 in 5 starts
  • Career vs. Giants: 1-2, 2.31 ERA (23 1/3 IP, 6 ER), 1.20 WHIP, 11.6 K/9 in 4 starts

Miller (2-2, 4.11 ERA) makes his 7th start and 37th appearance in what is expected to be an “opener” role. He has a 1.23 WHIP, 4.4 BB/9 and 10.3 K/9 through 35 innings. The Giants hope RHP Spencer Howard (0-1, 4.86 ERA) can pick up the bulk of the innings once Miller is removed. Howard has a 1.86 WHIP, 4.3 BB/9 and 7.0 K/9 in 16 2/3 innings.

  • Miller’s last outing: No-decision in start, 1 IP, 0 ER, 0 H, 1 BB, 2 K in 6-5 road loss at Cubs Wednesday
  • Allows .171 batting average when batter is ahead in count
  • Posts 1.17 OPS with 2 outs and RISP
  • Spencer’s last outing: 1 IP, 2 ER (3 R), 4 H, 1 BB, 3 K in relief of Miller in Wednesday loss to Cubs

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Cubs at Giants odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:32 p.m. ET.

  • Moneyline (ML): Cubs -120 (bet $120 to win $100) | Giants +100 (bet $100 to win $100)
  • Run line (RL)/Against the spread (ATS): Cubs -1.5 (+145) | Giants +1.5 (-175)
  • Over/Under (O/U): 7.5 (O: -105 | U: -115)

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Cubs at Giants picks and predictions

Prediction

Cubs 6, Giants 4

Moneyline

Steele is the Cubs’ best pitcher and he has yet to earn a win. His road splits show that when he is locked in he can dominate.

The Giants are 5-6 when playing as home underdogs. Plus, after a loss, the Cubs are 24-16, while the Giants are 21-20.

LEAN CUBS (-120).

Run line/Against the spread

The Cubs’ recent woes has makes me skittish on picking them against the spread as favorites. They’re also 14-17 in 1-run games.

AVOID.

Over/Under

The Cubs offense has stalled recently, but the Giants have some good trends toward the Over. San Francisco is 34-24-2 (58.6%) O/U in NL games, the 2nd-best mark in the majors. On no rest, the Over is 37-28-2 (56.9%) for the Giants.

The current line just seems too low. BET OVER 7.5 (-105).

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