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The San Diego Padres (78-80) and San Francisco Giants (78-80) meet for the final time this season on Wednesday. First pitch from Oracle Park is 9:45 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Padres vs. Giants odds and make our expert MLB picks and predictions for the best bets.
Season series: Padres lead 7-5
The Padres lost the opener 2-1, but bounced back Tuesday night with a 4-0 win. They have won 10 of their last 12 games, but are 1 game from being eliminated from Wild Card contention.
The Giants are 3-9 in their last 12 games. They also are 1 game from being eliminated.
Padres at Giants projected starters
RHP Matt Waldron vs. LHP Sean Manaea
Waldron (1-3, 4.58 ERA) makes his 6th start and 8th appearance. He has a 1.25 WHIP, 2.5 BB/9 and 7.4 K/9 in 35 1/3 innings.
- Last start: No-decision, 5 2/3 IP, 1 ER, 3 H, 2 BB, 9 K in 4-2 home win over St. Louis Cardinals on Friday
- Allowed 1 ER in 5 IP in a no-decision vs. Giants Aug. 31
Manaea (7-6, 4.51 ERA) makes his 10th start and 37th appearance. He has a 1.25 WHIP, 3.4 BB/9 and 9.7 K/9 in 111 2/3 innings.
- Last start: Win, 7 IP, 0 R, 3 H, 0 BB, 2 K in 5-1 victory at the Los Angeles Dodgers on Friday
- Is 2-1 with 2.00 ERA in 3 starts since rejoining the rotation
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Padres at Giants odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:21 p.m. ET.
- Moneyline (ML): Padres -110 (bet $110 to win $100) | Giants -110 (bet $110 to win $100)
- Run line (RL)/Against the spread (ATS): Padres -1.5 (+150) | Giants +1.5 (-185)
- Over/Under (O/U): 8.5 (O: -105 | U: -115)
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Padres at Giants picks and predictions
Prediction
Padres 5, Giants 2
Moneyline
The Padres have won 10 of their last 12 games and, while they are only 34-43 on the road this season, they have won 5 of their last 6 road games. Also, Waldron has only allowed 3 runs in his last 2 starts (11 IP).
You can take Padres straight up and it isn’t a bad play but you have win more on the spread, based on their recent play.
PASS.
Run line/Against the spread
Thirty of the Padres’ last 31 wins have been by 2 or more runs. They have covered the spread in 9 of their last 12 games. Meanwhile, 7 of the Giants’ last 8 losses have been by 2 or more runs.
BET PADRES -1.5 (+150).
Over/Under
Half of the 12 games between the teams have not reached 9 runs. The last 4 meetings have had fewer than 9. And 6 of the Padres’ last 7 games have not reached 9 runs.
BET UNDER 8.5 (-115).
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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.
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