Pittsburgh Pirates at Chicago Cubs odds, picks and predictions

Analyzing Wednesday’s Pittsburgh Pirates at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

The Pittsburgh Pirates (34-31) continue their 3-game series with the Chicago Cubs (29-37) Wednesday. First pitch from Wrigley Field is at 8:05 ET. Let’s analyze BetMGM Sportsbook’s lines around the Pirates vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Chicago leads 1-0

The Cubs took Tuesday’s opener 11-3 despite the Pirates scoring first on CF Jack Suwinski’s 1st-inning solo homer. Chicago LF Ian Happ responded with a 3-run blast in the bottom of the 1st, and after Suwinski’s 2nd homer of the game tied it at 3-3 in the 6th, the Cubs regained the lead on 1B Matt Mervis’ RBI single in the bottom of the 6th. Chicago increased the lead behind a 4-run 7th (bases-loaded hit by pitch, SS Dansby Swanson RBI single and 2-run single by PH Yan Gomes) and wrapped up the victory with a 3-run, 8th-inning homer by LF Christopher Morel — he replaced Happ in the top of the inning.

It was the Cubs’ 3rd victory in their last 4 games. Tuesday marked their return home after a 4-6 road trip through San Diego, Anaheim and San Francisco.

Pittsburgh, which leads the NL Central by 1 game over the Milwaukee Brewers, had just taken 2 of 3 at home from the New York Mets, winning Friday and Sunday. Tuesday was the Bucs’ 1st game of a 6-game trip, which will take them to Milwaukee after these 3 at Wrigley.

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Pirates at Cubs projected starters

RHP Osvaldo Bido vs. LHP Drew Smyly

Bido will make his major-league debut. He was 3-4 with a 4.55 ERA (55 1/3 IP, 28 ER), 1.30 WHIP, 4.2 BB/9 and 9.1 K/9 in 12 appearances (10 starts) at Triple-A Indianapolis.

  • Last start: Loss, 4 1/3 IP, 5 ER, 4 H, 5 B, 3 K in 15-7 rout by the visiting Triple-A Omaha Storm Chasers
  • Last 4 starts: 1-1, 6.75 ERA (20 IP, 15 ER), 19 H, 11 BB, 15 K
  • Allows .248 batting average when bases are empty and a .196 when runners are aboard

Smyly (5-4, 3.27 ERA) makes his 14th start. He has a 1.16 WHIP, 2.5 BB/9 and 7.7 K/9 in 71 2/3 innings.

  • Last start: Loss, 6 IP, 2 ER, 7 H, 3 BB, 4 K in a 3-1 loss at Los Angeles Angels Thursday
  • Home splits: 2-1, 3.52 ERA (30 2/3 IP, 12 ER), 0.98 WHIP, 9.7 K/9
  • .208 opponent batting average against righties; .318 vs. lefties

Pirates at Cubs odds

Provided by BetMGM Sportsbook;  access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:29 p.m. ET.

  • Moneyline (ML): Pirates +130 (bet $100 to win $130) | Cubs -155 (bet $155 to win $100)
  • Run line (RL)/Against the spread (ATS): Pirates +1.5 (-155) | Cubs -1.5 (+125)
  • Over/Under (O/U): 9 (O: +100 | U: -120)

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Pirates at Cubs picks and predictions

Prediction

Cubs 8, Pirates 3

Moneyline

At Wrigley, the Cubs match up well against good teams. They’ve won 10 of their last 11 home games against teams with a winning record (per Covers.com), but the -155 price is a bit too juicy for a team below .500.

AVOID.

Run line/Against the spread

With the Pirates pitcher making his MLB debut, I see a great opportunity for the Cubs. Bido averaged over 4 walks per 9 innings in the minors. The Cubs are 3rd in MLB in walks.

Bido will face a lot of pressure in his debut. LEAN CUBS -1.5 (+125).

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Over/Under

BET OVER 9 (+100).

There are several trends that back up this wager.

Against the NL Central, the Cubs have gone Over in 6 straight games.

The Over is 14-3-2 in the Pirates’ last 19 road games vs. left-handed starters.

The Over is 4-1 in the Pirates’ last 5 road games and 8-3 in the Pirates’ last 11 games following a loss.

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