WATCH: Denver Broncos At New York Giants, Week 1, Key Facts, Stats

See betting lines, statistical trends and relevant facts for the 2021 NFL season opener between the New York Giants and Denver Broncos.

The New York Giants open this season by hosting the Denver Broncos, which, based on recent history, isn’t necessarily good news for Big Blue fans. The Giants lost five of their past six home games against AFC opponents and eight of 10 overall against the AFC.

An encouraging note from a Giants’ perspective? Denver has lost four consecutive road openers; however, the Broncos are favored in this one. Go to Tipico Sportsbook for the most updated odds.

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