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The No. 5 USC Trojans (3-0, 1-0 Pac-12) and Arizona State Sun Devils (1-2, 0-0) meet Saturday at Mountain America Stadium. Kickoff is set for 10:30 p.m. ET (FOX). Below, we analyze BetMGM Sportsbook’s lines around the USC vs. Arizona State odds, and make our expert college football picks and predictions.
USC covered the spread as a 28-point home favorite with a 56-10 win vs. the Stanford Cardinal as the Under (70) hit Sept. 9 before its bye last week. The Trojans scored 49 points in the 1st half, and QB Caleb Williams finished 19-of-21 passing for 281 yards with 3 TDs and rushed for another score.
Arizona State failed to cover as a 4-point home underdog in a 29-0 loss vs. the Fresno State Bulldogs as the Under (47.5) cashed last Saturday. The Sun Devils were shut out for the 1st time since losing 28-0 at USC on Oct. 11, 2008.
These teams have played each other once since coach Lincoln Riley arrived at USC. Arizona State covered as a 24.5-point underdog in that meeting with a 42-25 road loss as the Over (61) hit Oct. 1, 2022.
USC is No. 5 in the US LBM Coaches Poll powered by USA TODAY Sports.
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USC at Arizona State odds
Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:57 a.m. ET.
- Moneyline (ML): USC -10000 (bet $10,000 to win $100) | Arizona State +2500 (bet $100 to win $2,500)
- Against the spread (ATS): USC -34.5 (-115) | Arizona State +34.5 (-105)
- Over/Under (O/U): 62.5 (O: -110 | U: -110)
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USC at Arizona State picks and predictions
Prediction
USC 55, Arizona State 13
Moneyline
USC (-10000) should have no trouble beating the 1-2 Sun Devils, but most people don’t want to risk $10,000 to win $100.
PASS. Lay the points and/or bet the total instead.
Against the spread
Arizona State is 0-3 ATS this season and has failed to cover by an average margin of 22.0 points per game.
USC is 2-1 ATS this season and has covered in back-to-back games as a favorite of 28 or more points. The Trojans failed to cover as 31-point home favorites in their lone ATS loss after getting backdoored by the San Jose State Spartans in the final 6 minutes of a 56-28 win.
USC has consistently played above expectations this season. BET USC -34.5 (-115).
Over/Under
The Over cashed in USC’s first 2 games this season and was just 5 points short of cashing in the Trojans’ win vs. Stanford. While USC seems to be improving defensively and has allowed just 17.3 points per game this season, I believe its offense is explosive enough to do most of the heavy lifting in this one and help the Over hit Saturday.
BET OVER 62.5 (-110).
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