TE George Kittle

Kittle’s been dominant in his career against the Rams. In five games, he has 27 catches for 458 yards and two touchdowns. That includes eight receptions for 103 yards in their last meeting. When Kittle is rolling, San Francisco’s offense becomes a nightmare to defend. Ideally the 49ers wouldn’t lean so heavily on their tight end, but that’s reality for now. He can take a step back from his 13-catch, 134-yard performance last week, but he’ll still need to be the focal point of the passing game.