New York Yankees at San Diego Padres odds, picks and predictions

Analyzing Sunday’s New York Yankees at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The New York Yankees (37-17) and San Diego Padres (27-28) meet Sunday for the finale of a 3-game series. First pitch from Petco Park is set for 4:10 p.m. ET (MLB Network). Let’s analyze FanDuel Sportsbook’s lines around the Yankees vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: New York leads 2-0

New York followed Friday’ 8-0 win over San Diego with a 4-1 victory Saturday while covering as a +110 road underdog. The Yankees have won 4 straight games, outscoring their opponents 17-1.

RHP Dylan Cease took the loss (6 2/3 IP, 4 ER, 8 H, 0 BB, 9 K) for the Padres, who have lost by a score of 8-0 in 2 of their last 3 home games.

Yankees at Padres projected starters

RHP Clarke Schmidt vs. RHP Joe Musgrove

Schmidt (5-2, 2.59 ERA) makes his 11th start. He has a 1.13 WHIP, 2.8 BB/9 and 9.9 K/9 in 55 2/3 IP.

  • Last start: Loss, 5 IP, 2 ER, 4 H, 2 BB, 6 K in a 6-3 loss vs. Seattle Tuesday
  • First career start vs. San Diego

Musgrove (3-4, 5.93 ERA) makes his 10th start. He has a 1.52 WHIP, 3.1 BB/9 and 8.0 K/9 in 44 IP.

  • Last start: Loss, 3 IP, 1 ER, 3 H, 2 BB, 3 K in a 2-0 loss at Cincinnati Tuesday
  • Career vs. Yankees: 1-0, 1.42 ERA (6 1/3 IP, 1 ER), 6 H, 0 BB, 6 K in 1 start

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Yankees at Padres odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:57 a.m. ET.

  • Moneyline (ML): Yankees -124 (bet $124 to win $100) | Padres +106 (bet $100 to win $106)
  • Run line (RL)/Against the spread (ATS): Yankees -1.5 (+126) | Padres +1.5 (-152)
  • Over/Under (O/U): 8.5 (O: -102 | U: -120)

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Yankees at Padres picks and predictions

Prediction

Yankees 6, Padres 4

Moneyline

New York (-124) is the much hotter team, entering on a 4-game win streak and being 8-2 in its last 10 games. The Yankees are also undefeated in their last 3 road games. NY has won 4 consecutive matchups vs. San Diego. But the run line offers a better value so PASS unless you don’t want to fool around with the spread.

Run line/Against the spread

BET YANKEES -1.5 (+126).

The Yankees are 31-23 ATS this year and their last 15 wins have all been by 2 or more runs. They have outscored Seattle 12-1 in the 1st 2 games of this series, so if you like them to win, you should like them to win by multiple runs.

Over/Under

BET OVER 8.5 (-102).

The Over has hit in 3 of San Diego’s last 4 games and in 6 of the last 10 outings. For New York, the Over is 5-2 in its last 7 games. The Over has also hit in 2 of the last 3 Yankees-Padres meetings in San Diego.

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New York Yankees at San Diego Padres odds, picks and predictions

Analyzing Saturday’s New York Yankees at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The New York Yankees (36-17) and San Diego Padres (27-27) play the middle contest a 3-game interleague series Saturday at Petco Park. First pitch is scheduled for 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Yankees vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Yankees lead 1-0

The Yankees routed the Padres 8-0 in the series opener behind LHP Carlos Rodon Friday night, getting to the previously white-hot RHP Yu Darvish early and often.

Former Padres OF Juan Soto collected 2 hits, including a double and a home run, while driving in 2 runs. Rodon twirled 6 scoreless innings and scattered 3 hits with 3 walks to improve to 5-2 while lowering his ERA to 2.95.

Darvish entered with a career-high 25 scoreless innings across his previous 4-plus starts, but he was touched up for 7 ER and 9 hits in 5 2/3 innings.

Friday marked the 12th time this season that a San Diego starting pitcher has allowed 5 or more runs in a game, and it was the 8th time the team has been down by 4 or more runs in the first 3 frames.

Yankees at Padres projected starters

RHP Marcus Stroman vs. RHP Dylan Cease

Stroman (3-2, 3.05 ERA) makes his 11th start. He has a 1.30 WHIP, 4.2 BB/9 and 7.7 K/9 in 56 innings.

  • Last start: No-decision, 7 1/3 IP, 1 ER, 3 H, solo HR, 1 BB, 6 K in 5-4 home loss vs. Seattle Mariners Monday
  • 2024 road splits: 2-0, 2.53 ERA (21 1/3 IP, 6 ER), 1.41 WHIP, .225 opponents’ batting average (OBA), 12 K across 4 starts

Cease (5-3, 3.05 ERA) makes his 11th start. He has a 0.93 WHIP, 3.1 BB/9 and 11.1 K/9 in 59 innings.

  • Last start: No-decision, 4 IP, 5 ER, 9 H, 2 HR, 3 BB, 5 K in 6-5 road win vs. Atlanta Braves Monday
  • 2024 home splits: 1-3, 4.03 ERA (22 1/3 IP, 10 ER), 1.03 WHIP, .185 OBA, 26 K in 4 starts

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Yankees at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:59 p.m. ET.

  • Moneyline (ML): Yankees +100 (bet $100 to win $100) | Padres -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Yankees +1.5 (-225) | Padres -1.5 (+165)
  • Over/Under (O/U): 7 (O: -130 | U: +100)

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Yankees at Padres picks and predictions

Prediction

Yankees 6, Padres 2

Moneyline

The YANKEES (+100) are a solid play at even-money behind Stroman.

The Padres (-120) have struggled in their home park, going 17-11 on the road and just 10-16 at home. San Diego’s pitching staff has an awful 4.64 ERA at Petco Park, and it is on pace to be the worst home ERA in club history.

New York routed San Diego in the opener, the pitching staff hasn’t allowed a run in the past 2 games, and the Padres are awful at home. Back the visitors.

Run line/Against the spread

The Yankees +1.5 (-225) will cost you more than 2 times your potential return, and that’s a silly amount of risk for such a small return.

PASS, and just bet New York straight up if you like it.

Over/Under

OVER 7 (-130) is a strong play at Petco Park.

The Yankees have cashed high in 5 of the past 6 games, with the offense going for 4 or more runs in 11 of the past 12 outings.

The general concern is the Padres, as they have struggled at home. Of course, they allow a ton of runs at home, too. Go lightly.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Additional MLB coverage:
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New York Yankees at San Diego Padres odds, picks and predictions

Analyzing Friday’s New York Yankees at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The New York Yankees (35-17) and San Diego Padres (27-26) begin a 3-game interleague series Friday at Petco Park. First pitch is scheduled for 9:40 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Yankees vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Yankees won 2-1 last season

The Yankees have the best record in the American League, percentage points ahead of the surprising Cleveland Guardians. They’re also 2nd-best in the majors behind the Philadelphia Phillies at 37-14.

New York dropped the first 2 games against the Seattle Mariners, but bounced back with a pair of wins Tuesday and Wednesday. It is 9-2 across the past 11 games, and the Over has cashed in 4 of the past 5 for New York.

The Padres took 2 of 3 from the Cincinnati Reds while winning 3 of 4 games from the Atlanta Braves, going 5-2 on the 7-game road trip. The Over is 7-3 in the past 10 games for San Diego.

Yankees at Padres projected starters

LHP Carlos Rodon vs. RHP Yu Darvish

Rodon (5-2, 3.27 ERA) makes his 11th start. He has a 1.20 WHIP, 2.6 BB/9 and 9.0 K/9 in 55 innings.

  • Last start: Win, 6 IP, 2 ER, 4 H, 1 HR, 2 BB, 6 K in 7-2 home win vs. Chicago White Sox Sunday
  • 2024 road splits: 2-2, 4.25 ERA (29 2/3 IP, 14 ER), 1.45 WHIP, .273 opponents’ batting average (OBA), 32 K across 6 starts

Darvish (4-1, 2.08 ERA) makes his 10th start. He has a 0.90 WHIP, 2.5 BB/9 and 8.7 K/9 in 47 2/3 innings.

  • Last start: Win, 7 IP, 0 ER, 2 H, 1 BB, 9 K (99 pitches) in 9-1 road win vs. Atlanta Braves Sunday
  • 2024 home splits: 2-1, 2.35 ERA (30 2/3 IP, 8 ER), 0.98 WHIP, .193 OBA, 30 K in 6 starts
  • Last 4 starts: 4-0, 0.00 ERA (24 IP), 10 H, 3 BB, 24 K

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Yankees at Padres odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:59 a.m. ET.

  • Moneyline (ML): Yankees -116 (bet $116 to win $100) | Padres -102 (bet $102 to win $100)
  • Run line (RL)/Against the spread (ATS): Yankees -1.5 (+146) | Padres +1.5 (-178)
  • Over/Under (O/U): 7.5 (O: -110 | U: -110)

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Yankees at Padres picks and predictions

Prediction

Padres 3, Yankees 2

Moneyline

The PADRES (-102) have the white-hot Darvish on the hill, and they’re short ‘dogs at home. Take advantage.

The last time Darvish allowed a run was on the road against the Los Angeles Dodgers April 14, an abbreviated start which landed him on the injured list due to a tight neck. He has returned better than ever, twirling 24 consecutive scoreless frames.

The Yankees (-116) have the best record in baseball, but San Diego is the play due to the pitching matchup. The southpaw Rodon has been a little giving on the road.

Run line/Against the spread

The Padres +1.5 (-178) are a little too pricey if you would like a little insurance and just can’t bring yourself to play San Diego straight up for some reason.

PASS, and just play Darvish and the Padres straight up for a better value.

Over/Under

UNDER 7.5 (-110) is a low number, and each of these teams have been cashing the Over on the regular. However, this is a strong pitching matchup, with Darvish posting donuts over his past 4 outings.

The Over is actually 3-1 in Darvish’s past 4 starts since returning, mainly because San Diego has been providing plenty of support. However, the Padres won’t pile up runs on the Yankees. The Under is 7-2-1 in New York’s past 10 games on the road, too.

Play our free daily Pick’em Challenge and win! Play now!

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Kevin J. Erickson on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Additional MLB coverage:
BaseballHQ Fantasy Baseball

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