Chicago White Sox at San Diego Padres odds, picks and predictions

Analyzing Sunday’s Chicago White Sox at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (89-66) welcome the Chicago White Sox (36-119) to Petco Park Sunday for the finale of a 3-game series. First pitch is set for 4:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the White Sox at Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Padres lead 2-0

The Padres beat the White Sox 3-2 to open the series Friday and then continued that streak with a 6-2 win Saturday, closing as heavy favorites in both. They have won 7 of their last 8 games and sit 2nd in the NL West. San Diego is 44-36 at home on the season and 79-76 against the spread (ATS).

The White Sox did sustain a 3-game winning streak Sept. 14-16, but are now riding a 4-game skid. They lost a series 2-1 to the Los Angeles Angels Monday through Wednesday. Chicago, despite that win streak, has still dropped 8 of its last 11 games. It is 16-61 on the road and 63-92 ATS.

White Sox at Padres projected starters

RHP Sean Burke vs. RHP Yu Darvish

Burke (1-0, 2.25 ERA) makes his 2nd start and 3rd appearance. He has a 1.38 WHIP, 3.4 BB/9 and 9.0 K/9 through 8 innings.

  • Last start: Win, 5 IP, 2 ER, 5 H, 2 BB, 5 K in 4-3 home victory over Oakland A’s Sunday
  • 2024 stats with Triple-A Charlotte: 2-6, 4.62 ERA (64 1/3 IP, 33 ER), 1.29 WHIP, 12.0 K/9 in 16 starts
  • Has never faced Padres

Darvish (6-3, 3.21 ERA) makes his 15th start. He has a 1.11 WHIP, 2.4 BB/9 and 8.4 K/9 through 70 innings.

  • Last start: Win, 6 IP, 0 ER, 3 H, 2 BB, 3 K in 3-1 home victory over Houston Astros Monday
  • 2024 home stats: 3-3, 3.75 ERA (48 IP, 20 ER), 1.21 WHIP, 8.3 K/9 in 10 starts
  • Career vs. White Sox: 3-2, 3.57 ERA (45 1/3 IP, 18 ER), 1.30 WHIP, 9.7 K/9 in 7 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

White Sox at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 9:20 a.m. ET.

  • Moneyline (ML): White Sox +280 (bet $100 to win $280) | Padres -350 (bet $350 to win $100)
  • Run line (RL)/Against the spread: White Sox +2.5 (-130) | Padres -2.5 (+110)
  • Over/Under (O/U): 7.5 (O: -120 | U: +100)

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White Sox at Padres picks and predictions

Prediction

Padres 5, White Sox 2

Moneyline

PASS.

The Padres (-350) are again a hefty favorite in this one, so much so that there is no moneyline play. The White Sox are unlikely to avoid a sweep here.

Run line/Against the spread

BET PADRES -2.5 (+110).

The Padres have been winning with ease as of late. They won a series against the Astros 2-1 Monday through Wednesday and swept the San Francisco Giants in 3 games Sept. 13-15.

The White Sox have lost 2 of their last 4 games by more than 2 runs. Chicago has scored a total of 7 runs over its last 4 games and will be facing a strong starting option in Darvish. Expect the Padres to again win by a sizable margin, and take PADRES -2.5 (+110).

Over/Under

BET UNDER 7.5 (+100).

The White Sox haven’t been able to score consistently as of late and have gone Under in 3 of their last 4 games. They are 0-3-1 O/U in that stretch. They are 66-80 O/U on the season. Chicago is 3-8-1 O/U in its last 12.

The Padres have gone Under in 5 of their last 6 games (0-5-1 O/U) and allowed a total of just 4 runs over their last 3.

Take UNDER 7.5 (+100).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Chicago White Sox at San Diego Padres odds, picks and predictions

Analyzing Friday’s Chicago White Sox at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

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The Chicago White Sox (36-117) open a 3-game series on the road against the San Diego Padres (87-66) Friday night. First pitch from Petco Park is at 9:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the White Sox vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting; Padres won 3-0 last season

The White Sox have only 9 wins since the All-Star break. They have lost 2 in a row after winning 3 straight and are coming off a 4-3 loss at the Los Angeles Angels on Wednesday.

The Padres lead the NL Wild Card race and trail the LA Dodgers by 4 games for the NL West lead. They have won 5 of their last 6 games and are coming off a series-clinching 4-0 win on Wednesday at home over the Houston Astros.

White Sox at Padres projected starters

LHP Garrett Crochet vs. RHP Joe Musgrove

Crochet (6-12, 3.78 ERA) makes his 31st start. He has a 1.09 WHIP, 2.1 BB/9 and 12.7 K/9 in 138 IP.

  • Last start: Loss, 4 IP, 1 ER, 3 H, 0 BB, 4 K in 2-0 home loss to Oakland A’s last Friday
  • Has not had a win since June 7
  • Has not pitched more than 4 IP in last 9 starts
  • Has pitched 1 scoreless inning in his career vs. Padres

Musgrove (6-5, 4.23 ERA) makes his 18th start. He has a 1.23 WHIP, 2.3 BB/9 and 8.9 K/9 in 87 1/3 IP.

  • Last start: Win, 6 IP, 0 R, 3 H, 0 BB,8 K in 8-0 road win over San Francisco Giants on Saturday
  • Is 3-1 with 2.37 ERA in 7 starts since returning from injured list
  • Has 7 1/3 scoreless innings in 3 career games (1 start) vs. Chicago

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

White Sox at Padres odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 8:46 a.m. ET.

  • Moneyline (ML): White Sox +200 (bet $100 to win $200) | Padres -250 (bet $250 to win $100)
  • Run line (RL)/Against the spread (ATS): White Sox +1.5 (-110) | Padres -1.5 (-110)
  • Over/Under (O/U): 7 (O: -110 | U: -110)

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White Sox at Padres picks and predictions

Prediction

Padres 4, White Sox 2

Moneyline

At this point, you should probably never bet on the White Sox on the moneyline. They have the fewest wins in all of baseball. They have only 9 wins since the All-Star Game.

The Padres have won 10 of their last 15, but betting them at -250 isn’t worth the action.

PASS.

Run line/Against the spread

Twelve of Chicago’s last 13 losses have been by at least 2 runs while 10 of the Padres’ last 13 wins have been by 2 or more runs.

The White Sox are 31-44 ATS on the road.

BET PADRES -1.5 (-110).

Over/Under

Six of the Padres’ last 7 games have not reached 8 total runs while 4 of the last 6 for Chicago have not either. Five of their last 8 losses have not either.

Five of Musgrove’s 7 starts since returning from IL had not reached 8 total runs.

BET UNDER 7 (-110).

Play our free daily Pick’em Challenge and win! Play now!

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Jess Root on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Fantasy baseball help from BaseballHQ.com:
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