Titans vs 49ers – Syndication Server

San Francisco 49ers vs. Tennessee Titans live, streaming, TV channel, time, how to watch

The Tennessee Titans will host the San Francisco 49ers at Nissan Stadium on Thursday night as both teams fight for playoff position.

The Titans have struggled without Derrick Henry but they are in need of a win and we know when Mike Vrabel plays in primetime he seems to get it done. As for the 49ers, they are one of the hottest teams in the NFL at the moment, having won five of their last six games even if it was against opponents with losing records, it’s still the NFL.

This will be a great game, here is everything you need to know to stream the action on Thursday.

San Francisco 49ers vs. Tennessee Titans

When: Thursday, December 23
Time: 8:20 p.m. ET
TV Channel: FOX/NFL Network
Live Stream: fuboTV (watch for free)

How to watch the NFL this season

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NFL Football Odds and Betting Lines

NFL odds courtesy of Tipico Sportsbook. Odds last updated Thursday at 6:15 p.m. ET.

San Francisco 49ers (-3.5) vs. Tennessee Titans

O/U: 45.5

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TNF: San Francisco 49ers vs. Tennessee Titans live stream, TV channel, time, how to watch

The San Francisco 49ers will face the Tennessee Titans in NFL action on Thursday night from Nissan Stadium in Nashville, Tennessee.

The 49ers come into tonight’s game having won their last two games and five out of their last six. Jimmy Garoppolo has been hot with Deebo Samuel picking up a ton of yards as of late. Meanwhile, the Titans will look to bounce back after a 19-13 loss to the Steelers as they go for their 10th win of the season.

This should be a good one tonight, here is everything you need to know to catch all the action on Thursday night.

San Francisco 49ers vs. Tennessee Titans

When: Thursday, December 23
Time: 8:20 p.m. ET
TV Channel: FOX/NFL Network, Amazon Prime Video
Live Stream: Amazon Prime Video (stream with free trial)

How to watch Thursday Night Football this season

Amazon Prime Video & Fire TV have you covered every Thursday night this NFL season with Thursday Night Football being broadcast across Prime Video.

Watch TNF, movies, and TV shows on the web or with the Prime Video app on your iOS and Android phone, tablet, or select Smart TVs.

NFL Football Odds and Betting Lines

NFL odds courtesy of Tipico Sportsbook. Odds last updated Thursday at 1:30 p.m. ET.

San Francisco 49ers (-3.5) vs. Tennessee Titans

O/U: 44.5

Want some action on the NFL? Place your legal sports bets on this game or others in CO, IN, NJ, and WV.

What Titans are saying about 49ers ahead of Week 16 matchup

Titans head coach Mike Vrabel was very complimentary of 49ers QB Jimmy Garoppolo.

Onto Week 16 of the 2021 NFL season, the Tennessee Titans head back home to host a San Francisco 49ers team that has won five out of their last six games.

The Titans have lost their last three out of four contests, but they can officially clinch the AFC South with a win and an Indianapolis loss.

The 49ers are led by quarterback Jimmy Garoppolo, who has averaged just over 236 yards per game during San Francisco’s recent hot stretch, to go along with a robust 72-percent completion rate.

“He’s taking care of the football, he’s been accurate,” Titans head coach Mike Vrabel said of Garoppolo on Tuesday. “He seems to be in command of everything that they’re doing. I mean, he’s playing well, he’s got a very good completion percentage, and they’re number one in the red zone.”

The Titans’ offense will look to get back on track against a defense that is 12th against the run (108.6 YPG) and seventh in passing yards allowed (213.2 YPG).

Here’s everything the Titans are saying in advance of their matchup with the 49ers on “Thursday Night Football.”

6 burning questions for Titans ahead of Week 16 game vs. 49ers

The Titans desperately need their offense to wake up in Week 16 against the Niners.

The Tennessee Titans will have little time to reflect on their disappointing 19-13 loss in Pittsburgh on Sunday. They’ll turn right around and host the red-hot San Francisco 49ers on “Thursday Night Football.”

The 49ers are currently riding a two-game win streak in the series, with the Titans’ last win at home against San Francisco coming in November 2005.

Despite losing three out of their last four, Tennessee still holds a one-game lead and the tiebreaker over a second-place Indianapolis Colts team that is making a lot of noise behind superstar running back, Jonathan Taylor.

The Titans are still without Derrick Henry, but they are inching ever closer to getting their MVP back for the playoffs, and they can clinch the AFC South with a win over the 49ers on Thursday, combined with a Colts loss to the Arizona Cardinals on Saturday.

In advance of their matchup, here are five questions to keep tabs on leading up to and throughout the Titans and 49ers contest in Week 16.