Tampa Bay Buccaneers at Buffalo Bills odds, picks and predictions

Analyzing Thursday’s Tampa Bay Buccaneers at Buffalo Bills odds and lines, with expert NFL picks and predictions.

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The Tampa Bay Buccaneers (3-3) and Buffalo Bills (4-3) meet for Thursday Night Football in Week 8 at Highmark Stadium. Kickoff is scheduled for 8:15 p.m. ET (Prime Video). Below, we analyze FanDuel Sportsbook’s lines around the Buccaneers vs. Bills odds, and make our expert NFL picks and predictions.

The Buccaneers are coming off a disappointing 16-13 setback at Raymond James Stadium in Tampa against the division rival Atlanta Falcons. The offense has had a power outage in the past 2 games, totaling just 19 points across the past 2 losses, spoiling a tremendous defensive effort.

Tampa has allowed just 18.0 PPG in the past 2 games, and the Bucs are allowing just 17.4 PPG overall, cashing the Under in 5 of 6 outings to date.

The Bills will also be happy to get back in action with a quick turnaround. Buffalo was stunned 29-25 on the road against a bad New England Patriots team. The Bills have dropped 2 of the past 3 games overall, while failing to cash against the spread (ATS) in 3 in a row. The offense has dropped off significantly, averaging just 19.7 PPG in the past 3 games after going for 41.0 PPG in the previous 3 contests.

Tampa hasn’t faced an AFC opponent so far this season. Buffalo is 2-0 straight up (SU) and ATS against the NFC in 2023.

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Buccaneers at Bills odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at 5:33 p.m. ET.

  • Moneyline (ML): Buccaneers +320 (bet $100 to win $320) | Bills -405 (bet $405 to win $100)
  • Against the spread (ATS): Buccaneers +8.5 (-110) | Bills -8.5 (-110)
  • Over/Under (O/U): 42.5 (O: -115 | U: -105)

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Buccaneers at Bills key injuries

Buccaneers

  • OG Matt Feiler (knee) out
  • WR Chris Godwin (neck) questionable
  • QB Baker Mayfield (knee) questionable
  • S Kaevon Merriweather (ankle) out
  • DT Vita Vea (groin) questionable

Bills

  • TE Dawson Knox (wrist) out
  • LB Von Miller (knee) available
  • TE Quintin Morris (ankle) out
  • DT Ed Oliver (toe) questionable
  • DT Jordan Phillips (back) available
  • LB Baylon Spector (hamstring) out

Buccaneers at Bills picks and predictions

Prediction

Bills 23, Buccaneers 18

Moneyline

The Bills (-405) will cost you more than 4 times your potential return, and that’s risky business. Yes, Buffalo will be angry after a stunning loss against 1 of the worst teams in the NFL last weekend. However, the Bills offense, which has been struggling lately, faces a stiff test against one of the better defenses in the NFC.

PASS, and focus on the spread instead.

Against the spread

The BUCCANEERS +8.5 (-110) were my initial lean, but Mayfield was limited in practice. If he is ruled out, and backup QB Blaine Gabbert is entrusted with the start, then it’s all-in on the Bills -8.5 (-110). The line is likely to shift dramatically, too. Mayfield could very well be a game-time decision, as he tests his knee in pregame warmups, so be careful.

Over/Under

UNDER 42.5 (-105) is worth playing lightly, but again, be careful.

The Bills defense was dinged for 29 points by a shaky Patriots defense, so even the Bucs could get loose for some points here. That’s not expected, however. And the Bills offense has really had its issues lately, and that isn’t likely to be ironed out on a short week against a very good defensive unit.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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First look: Tampa Bay Buccaneers at Buffalo Bills odds and lines

Looking at Thursday’s Tampa Bay Buccaneers at Buffalo Bills Week 8 NFL odds, lines and trends. Here’s what you need to know.

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The Tampa Bay Buccaneers (3-3) and Buffalo Bills (4-3) meet for Thursday Night Football at Highmark Stadium. Kickoff is scheduled for 8:15 p.m. ET (Prime Video). Below, we look at Buccaneers vs. Bills odds from FanDuel Sportsbook. Also see: SportsbookWire’s NFL picks and predictions.

The Buccaneers were on the short end of a 16-13 loss at home against the Atlanta Falcons in Week 7, losing on a last-second field goal. Tampa Bay has dropped 3 of the past 4 games, while also going 1-3 against the spread (ATS). The Under has cashed in 4 in a row, and 5 of 6 games overall.

The Bills are coming off a stunning 29-25 road loss against the New England Patriots as 8.5-point favorites. The 29 points allowed were actually the most for Buffalo all season. Buffalo has dropped 2 of the past 3 games, while failing to cover each of the previous 3 outings.

FOOTBALL NEVER STOPS
Live games, analysis and more 7 days a week: Get ESPN+

Buccaneers at Bills odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 9:45 a.m. ET.

  • Moneyline (ML): Buccaneers +320 (bet $100 to win $320) | Bills -405 (bet $405 to win $100)
  • Against the spread (ATS): Buccaneers +7.5 (-105) | Bills -7.5 (-115)
  • Over/Under (O/U): 41.5 (O: -110 | U: -110)

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2023 betting stats

  • ML: Buccaneers 3-3 | Bills 4-3
  • ATS: Buccaneers 3-3 | Bills 3-4
  • O/U: Buccaneers 1-5 | Bills 3-4

Buccaneers at Bills head-to-head

These teams last met on Dec. 12, 2021, with the Buccaneers coming away with a memorable 33-27 overtime victory as 3.5-point home favorites behind future Hall-of-Fame QB and Bills nemesis Tom Brady. The Over (53) cashed in that game, and is 3-1 in the past 4 meetings dating back to Sept. 20, 2009.

The last time these teams met in Western New York, the Bills came away with a 30-27 win while pushing at most shops as 3-point favorites.

Play our free daily Pick’em Challenge and win! Play now!

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Kevin J. Erickson on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Access more NFL coverage:

TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire

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