Tag: St. Louis Cardinals vs. Chicago Cubs odds predictions pick betting line spread

St. Louis Cardinals at Chicago Cubs odds, picks and predictions

Analyzing Saturday’s St. Louis Cardinals at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (56-54) and Chicago Cubs (54-58) play the 3rd game of a 4-game series Saturday. First pitch from Wrigley Field is set for 2:20 p.m. ET (MLB Network). Let’s analyze FanDuel Sportsbook’s lines around the Cardinals vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Cardinals lead 6-5

St. Louis dropped another game at Wrigley 6-3 Friday night. RHP Erick Fedde was roughed up in his debut for the Cardinals (5 IP, 5 ER, 6 H, 2 HR, 0 BB, 4 K). All 3 of the Cardinals’ runs were scored on bases-loaded walks. The Cardinals are 27-29 on the road and 56-54 against the spread (ATS).

The Cubs won their 3rd straight game Friday behind homers from C Christian Bethancourt and 1B Michael Busch in a 5-run 2nd inning. RHP Javier Assad held St. Louis to 1 earned run but only lasted 4 1/3 innings. Chicago is 29-25 at Wrigley Field and 52-60 ATS

Cardinals at Cubs projected starters

RHP Kyle Gibson vs. RHP Jameson Taillon

Gibson (7-4, 3.97 ERA) makes his 21st start. He has a 1.34 WHIP, 3.7 BB/9 and 8.1 K/9 in 113 1/3 IP.

  • Last start: Loss, 5 IP, 2 ER, 6 H, 3 BB, 0 K in 14-3 home loss against Washington Nationals July 27
  • 2024 road splits: 5-1, 3.13 ERA (60 1/3 IP, 21 ER), 1.08 WHIP, 9.5 K/9 in 10 starts
  • 2024 vs. Cubs: 1-0, 3.27 ERA (11 IP, 4 ER), 1.36 WHIP, 7.4 K/9 in 2 starts

Taillon (7-6, 3.35 ERA) makes his 19th start. He has a 1.17 WHIP, 1.9 BB/9 and 7.1 K/9 in 104 2/3 IP.

  • Last start: Loss, 4 1/3 IP, 6 ER, 6 H, 1 BB, 4 K in 7-1 road loss to Cincinnati Reds Monday
  • 2024 home splits: 5-3, 2.68 ERA (57 1/3 IP, 17 R (16 ER), 1.14 WHIP, 8.0 K/9 in 9 starts
  • 2024 vs. Cardinals: 1-1, 4.15 ERA (17 1/3 IP, 8 ER), 1.50 WHIP, 4.7 K/9 in 3 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Cardinals at Cubs odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:15 a.m. ET.

  • Moneyline (ML): Cardinals +100 (bet $100 to win $100) | Cubs -118 (bet $118 to win $100)
  • Run line (RL)/Against the spread: Cardinals -1.5 (+164) | Cubs +1.5 (-200)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

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Cardinals at Cubs picks and predictions

Prediction

Cubs 6, Cardinals 4

Moneyline

BET CUBS (-118).

All the momentum is with the Cubs right now, and I’m going to ride that into a victory Saturday. Taillon has a 2.68 ERA at home and has won 2 of his last 3 starts at Wrigley. He just beat the Cardinals at Busch Stadium July 14. Chicago’s ERA at home is also nearly a full point than its ERA in away games (3.28 vs. 4.27).

Gibson does not have a good history against Chicago with a record of 1-4 and an ERA of 5.46. He had a 3.33 ERA in May, 3.97 in June and 4.91 in July — not a good trend as he gets his 1st start of August.

Run line/Against the spread

PASS.

I’m going to keep my bet to the moneyline.

Over/Under

BET OVER 7.5 (-105).

It’s hard to ignore the trends with this one. These 2 teams have gone Over in their last 5 head-to-head meetings, including the 1st 2 games of this series. The Cardinals have also been Over in 5 straight games.

The Over has hit in 5 of Gibson’s last 6 starts, while it hit in 3 of Taillon’s last 5.

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St. Louis Cardinals at Chicago Cubs odds, picks and predictions

Analyzing Friday’s St. Louis Cardinals at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (56-53) and Chicago Cubs (53-58) face off Friday in game 2 of a 4-game series. First pitch from Wrigley Field is set for 2:20 p.m. ET (MLB Network). Let’s analyze FanDuel Sportsbook’s lines around the Cardinals vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Cardinals lead 6-4

Chicago came away with a 5-4 series-opening win as a -111 home favorite Thursday. The Cubs scored 3 in the bottom of the 9th, capped by a walk-off RBI double from PH Mike Tauchman to complete the comeback.

St. Louis closer Ryan Helsley, who started the bottom of the 9th, took the loss. He allowed a 1-out solo homer to DH Cody Bellinger, a 2-out single to 2B Nico Hoerner followed by a stolen base, SS Dansby Swanson’s RBI double and Tauchman’s game-ending RBI double.

Thursday’s loss ended a 2-game win streak for the Cardinals, while the Cubs have won 2 in a row.

Cardinals at Cubs projected starters

RHP Erick Fedde vs. RHP Javier Assad

Fedde makes his 1st start for St. Louis after being acquired in a trade from the Chicago White Sox. The UNLV product was 7-4 with a 3.11 ERA (121 2/3 IP, 42 ER), 1.14 WHIP, 2.5 BB/9 and 8.0 K/9 in 21 starts for the ChiSox.

  • Last start: Loss, 4 IP, 3 ER, 6 H, 2 BB, 4 K in 6-3 home setback vs. Seattle Mariners Saturday
  • Career vs. Cubs: 0-0, 5.51 ERA (16 1/3 IP, 10 ER), 18 H, 5 HR, 5 BB, 22 K in 3 starts
  • 2024 vs. Cubs: 1 start, no-decision, 5 IP, 3 ER, 6 H, 0 BB, 7 K in 7-6 walk-off loss at Wrigley June 5

Assad (5-3, 3.23 ERA) makes his 20th start. He has a 1.35 WHIP, 4.0 BB/9 and 8.2 K/9 through 94 2/3 innings.

  • Last start: Win, 6 IP, 3 ER, 5 H, 1 BB, 5 K in 7-3 victory at Kansas City Royals Sunday
  • Career vs. Cardinals: 0-2, 3.80 ERA (23 2/3 IP, 10 ER), 24 H, 14 BB, 20 K across 3 starts and 5 relief appearances
  • 2024 vs. Cardinals: 0-1, 8.59 ERA (7 1/3 IP, 7 ER), 12 H, 4 HR, 5 BB, 8 K in 2 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Cardinals at Cubs odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Friday at 4:05 a.m. ET.

  • Moneyline (ML): Cardinals -112 (bet $112 to win $100) | Cubs -104 (bet $104 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals -1.5 (+150) | Cubs +1.5 (-182)
  • Over/Under (O/U): 7.5 (O: -110 | U: -110)

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Cardinals at Cubs picks and predictions

Prediction

Cardinals 6, Cubs 5

Moneyline

LEAN CARDINALS (-112).

St. Louis was 2-1 in its last 3 matchups vs. the Cubs in Chicago prior to Thursday’s late-game choke. In a game with the margins as tight as this one, that advantage coupled with the fact that the Cards are 6-4 in their last 10 vs. the Cubs is enough to make me lean toward St. Louis.

Fedde is also a slightly better pitcher than Assad, furthering the Cardinals’ edge.

This is an extremely risky bet as these teams have played each other very tightly recently and as I do not see either team having a major advantage entering this matchup.

Run line/Against the spread

PASS. 

I like the Cubs to cover here as +1.5 (-182) underdogs as 5 of the last 10 matchups between these squads have come down to a 1-run finish, but the line is set too heavy to risk betting on. Bet on the moneyline and/or total instead.

Over/Under

BET OVER 7.5 (-110).

The Over has hit in each of St. Louis’ last 4 games and is 6-1 in its last 7.

For Chicago, the Over is 2-0 in its last 2 games and 4-2 in its last 6.

The Over has also hit in each of the last 4 St. Louis-Chicago matchups.

Be aware that the Under is 6-4 in Chicago’s last 10 overall.

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St. Louis Cardinals at Chicago Cubs odds, picks and predictions

Analyzing Sunday’s St. Louis Cardinals at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (34-35) and Chicago Cubs (34-37) finish their 3-game series at Wrigley Field on Sunday. First pitch is scheduled for 1:05 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Cardinals vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Cardinals lead 3-1

After losing 3-0 on Friday, the Cubs won 5-1 on Saturday as LHP Shota Imanaga continues to be Chicago’s most valuable player. He is 7-1 with a 1.89 ERA and 0.99 WHIP. On Saturday he threw 7 innings, giving up 4 H, 1 ER, 0 BB with 6 K.

The only Cardinal run was a sacrifice by 3B Nolan Arenado in the 4th inning. But in the bottom of the inning, the Cubs responded with 2 runs and went on to win as -185 favorites.

Cardinals at Cubs projected starters

RHP Miles Mikolas vs. RHP Jameson Taillon

Mikolas (4-6, 4.85 ERA) makes his 15th start. He has a 1.19 WHIP, 1.7 BB/9 and 6.8 K/9 in 78 IP.

  • Last start: No decision, 7 IP, 0 ER, 1 H, 1 BB, 6 K in 2-1 home loss against Pittsburgh Pirates Tuesday.
  • 2024 road stats: 4-4, 5.04 ERA (44 2/3 IP, 25 ER) in 8 starts

Taillon (3-2, 3.09 ERA) makes his 11th start. He has a 1.30 WHIP, 2.3 BB/9 and 6.5 K/9 in 55 1/3 IP.

  • Last start: No decision, 6 IP, 0 ER, 4 H, 1 BB, 5 K in 5-2 road loss to the Tampa Bay Rays Tuesday
  • 2024 home stats: 3-1, 3.42 ERA (26 1/3 IP, 10 ER) in 5 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Cardinals at Cubs odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:21 a.m. ET.

  • Moneyline (ML): Cardinals +116 (bet $100 to win $116) | Cubs -136 (bet $136 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-166) | Cubs -1.5 (+138)
  • Over/Under (O/U): 11 (O: -110 | U: -110)

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Cardinals at Cubs picks and predictions

Prediction

Cubs 5, Cardinals 4

Moneyline

Despite their recent backslide, the Cubs are 13-9 straight up as a home favorite while the Cardinals are 12-16 as a road dog.

BET CUBS (-136).

Run line/Against the spread

As a favorite the Cubs are a paltry 8-22, I would rather pick them on the moneyline.

PASS.

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Over/Under

Both teams are on extensive Under streaks that cannot be sustained. The Cardinals haven’t hit the Over in 6 straight games while the Cubs Under streak is 8 games.

After a win the Cubs have the 4th best Over rate at 56.3% (18-14-1) so I expect some offense. But St. Louis in divisional games has the best Under record (12-5) and the current line is incredibly high for 2 teams that have struggled to score.

LEAN UNDER 11 (-110).

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St. Louis Cardinals at Chicago Cubs odds, picks and predictions

Analyzing Saturday’s St. Louis Cardinals at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (34-34) and Chicago Cubs (33-37)) face off in the Saturday game of a 3-game weekend series. First pitch from Wrigley Field is set for 2:20 p.m. ET (FS1). Let’s analyze FanDuel Sportsbook’s lines around the Cardinals vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: St. Louis leads 3-0

St. Louis picked up a 3-0 win in Friday’s series opener and covered as a +111 road underdog — the Under (7.5) cashed. The Cardinals broke a scoreless tie in the 8th with a solo HR from C Padro Pages and added 2 more runs in the 9th on RBIs from DH Ivan Herrera and OF Dylan Carlson to come away with the win, St. Louis’ 3rd in a row. SP Kyle Gibson was superb, yielding just 2 hits in 7 innings, while striking out 6.

Chicago, which finished with just 3 hits, has dropped back-to-back games and 6 of its last 8. The Cubs have only hit .212 and averaged 2.6 runs per game during the 8-game stretch. The pitching staff has given up at least 3 runs in each of the Cubs’ last 19 losses.

Cardinals at Cubs projected starters

RHP Andre Pallante vs. LHP Shota Imanaga

Pallante (2-2, 4.88 ERA) makes his 4th start and 13 appearance. He has a 1.58 WHIP, 4.5 BB/9 and 6.4 K/9 through 24 innings.

  • Last start: Win, 5 IP, 0 ER, 3 H, 1 BB, 6 K in 5-1 home victory vs. Colorado Rockies Sunday
  • 2024 road splits: 1-1, 4.00 ERA (9 IP, 4 ER), 11 H, 4 BB, 6 K in 5 outings (1 start)
  • Career vs. Cubs: 0-1, 2.41 ERA (18 2/3 IP, 5 ER), 17 H, 9 BB, 9 K in 9 outings (2 starts)

Imanaga (6-1, 1.96 ERA) makes his 13th start. He has a 1.03 WHIP, 1.4 BB/9 and 9.4 K/9 through 69 innings.

  • Last start: Win, 6 2/3 IP, 2 ER, 5 H, 1 BB, 7 K in 4-2 win at Cincinnati Reds Sunday
  • 2024 home splits: 2-0, 1.31 ERA (34 1/3 IP, 5 ER), 0.84 WHIP, 10.0 K/9 in 6 starts
  • Never faced Cardinals before (MLB debut: April 1, 2024)

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Cardinals at Cubs odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:27 a.m. ET.

  • Moneyline (ML): Cardinals +140 (bet $100 to win $140) | Cubs -166 (bet $166 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-154) | Cubs -1.5 (+128)
  • Over/Under (O/U): 8 (O: -106 | U: -114)

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Cardinals at Cubs picks and predictions

Prediction

Cardinals 4, Cubs 2

Moneyline

BET CARDINALS (+140).

St. Louis is the slightly hotter team, going 6-4 in its last 10; Chicago is 4-6 in its last 10. The Cardinals are also 4-1 in their last 5 overall and have won back-to-back road games.

The Cardinals are 4-0 in the last 4 head-to-head meetings vs. the Cubs dating back to last season.

Run line/Against the spread

PASS.

The Cardinals +1.5 (-154) should cover here, but their run line requires too much juice. Bet on the moneyline and/or Over/Under instead.

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Over/Under

BET UNDER 8 (-114).

The Under has hit in 5 consecutive games for St. Louis and is 7-3 in its last 10 overall. For Chicago, the Under is 7-0 in its last 7 games. The Under has also hit in back-to-back St. Louis-Chicago matchups and is 5-1 in the last 6 meetings.

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St. Louis Cardinals at Chicago Cubs odds, picks and predictions

Analyzing Friday’s St. Louis Cardinals at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (33-34) and Chicago Cubs (33-35) begin a 3-game series Friday. First pitch from Wrigley Field is slated for 2:20 p.m. ET (MLB Network). Let’s analyze FanDuel Sportsbook’s lines around the Cardinals vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Cardinals lead 2-0

The Cardinals finished 4-3 in their 7-game homestand after Thursday’s 4-3 over the Pittsburgh Pirates. LF Brendan Donovan took Pirates RHP Mitch Keller deep in the 6th inning to snap the 3-all tie. St. Louis also got a 2-run HR from 1B Paul Goldschmidt. They are 16-19 away from Busch Stadium as they head off on a 6-game road trip.

The Cubs are thrilled to be heading back to Chicago after going 2-5 over their 7-game road trip. They dropped their series finale against the Tampa Bay Rays 3-2 on Thursday. Starting LHP Justin Steele was the hard-luck loser (6 IP, 0 ER, 3 H, 5 K) with the only offense coming on a fielder’s choice ground out followed by a sacrifice from C Yan Gomes.

Cardinals at Cubs projected starters

RHP Kyle Gibson vs. LHP Jordan Wicks

Gibson (4-2, 3.76 ERA) makes his 14th start. He has a 1.27 WHIP, 3.5 BB/9 and 7.9 K/9 in 76 2/3 IP.

  • Last start: No-decision, 6 IP, 3 ER, 8 H, 2 BB, 7 K in 6-5 loss against the Colorado Rockies Saturday
  • Last start vs Cubs: Loss, 6 IP, 3 ER, 3 H, 2 BB, 7 K in 3-2 road loss June 17, 2023, as a member of the Baltimore Orioles
  • Has lost all 4 of his career starts against the Cubs

Wicks (1-2, 4.44 ERA) makes his 6th start. He has a 1.48 WHIP, 3.4 BB/9 and 10.3 K/9 in 26 1/3 IP.

  • Last start: Win, 6 IP, 2 ER, 5 H, 0 BB, 4 K in 7-2 victory against the Houston Astros on April 23
  • Has never started against the Cubs
  • 2024 home splits: 1-1, 3.38 ERA (10 2/3 IP, 4 ER), 1.13 WHIP, 9.3 K/9 in 2 starts

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Cardinals at Cubs odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:23 a.m. ET.

  • Moneyline (ML): Cardinals -104 (bet $104 to win $100) | Cubs -112 (bet $112 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals -1.5 (+158) | Cubs +1.5 (-192)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Cardinals at Cubs picks and predictions

Prediction

Cubs 4, Cardinals 3

Moneyline.

BET CUBS (-104).

I like Chicago to take the opener of this series at home. The Cubs have owned Gibson and it doesn’t matter what team he’s pitching for at the time. He’s 0-4 with a 6.64 ERA against the Cubs. Gibson has also allowed at least 3 ER in both of his starts this month.

Chicago begins a 9-game homestand, which is music to their ears since they are 18-13 at Wrigley Field.

Run line/Against the spread

PASS.

I’ll save my wager for the money line in this game.

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Over/Under

BET UNDER 8 (-105)

It’s hard not to love the Under in this game with all the trends pointing you that direction. In their last 5 meetings, the Under has hit in 4 of them. The Cubs have been Under in their last 6 games and the Cardinals have been Under in their last 4.

Wicks has allowed 2 runs or fewer in 4 of his last 5 starts while Gibson has allowed a grand total of 7 ER over his last 4 starts (21 2/3 IP). This game should be low scoring.

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St. Louis Cardinals at Chicago Cubs odds, picks and predictions

Analyzing Sunday’s St. Louis Cardinals at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

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The St. Louis Cardinals (44-55) end their 4-game series with the Chicago Cubs (47-51) Sunday. First pitch from Wrigley Field is at 2:20 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 4-4

Multiple rain delays pushed Saturday’s game back for hours and the Cubs  used RHP Michael Fulmer as an opener before LHP Drew Smyly took over. Despite the strategic move by manager David Ross, the Cubs were playing catch-up the whole day.

Chicago trailed 1-0, 3-1, 5-3 and 6-5 before moving in front for the 1st time with 3 runs in the 6th inning. Cody Bellinger had a 2-run single and Seiya Suzuki followed with an RBI single, giving the Cubs an 8-6 lead. Bellinger drove in 4 runs and the 2019 NL MVP is batting .382 (42 for 110) with 21 RBI in his last 30 games.

The Cardinals, who are in 4th place and trail their NL Central rivals by 3 1/2 games, got HRs from Lars Nootbaar and Nolan Gorman. St. Louis has dropped 2 in a row after a 6-game win streak.

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Cardinals at Cubs projected starters

LHP Jordan Montgomery vs. RHP Jameson Taillon

Montgomery (6-7, 3.14 ERA) makes his 20th start. He has a 1.22 WHIP, 2.4 BB/9 and 8.3 K/9 in 109 innings.

  • Last start: No-decision, 6 IP, 1 ER, 6 H, 2 BB, 5 K in a 5-2 home win vs. Miami Marlins on Tuesday
  • Has .234 opponent batting average in his 9 road starts

Taillon (3-6, 6.05 ERA) makes his 17th start. He has a 1.39 WHIP, 2.7 BB/9 and 7.8 K/9 in 77 1/3 innings.

  • Last start: No-decision, 5.2 IP, 3 ER, 7 H, 1 BB, 4 K in 17-3 win versus the Washington Nationals on Tuesday
  • Home starts: 1-4, 7.06 ERA and a 1.59 WHIP

Cardinals at Cubs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:12 a.m. ET.

  • Moneyline (ML): Cardinals -145 (bet $145 to win $100) | Cubs +120 (bet $100 to win $120)
  • Run line (RL)/Against the spread (ATS): Cardinals -1.5 (+110) | Cubs +1.5 (-135)
  • Over/Under (O/U): 9 (O: -120 | U: +100)

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Cardinals at Cubs picks and predictions

Prediction

Cardinals 3, Cubs 2

Moneyline

You woud expect Cubs’ starter Taillon to be more relaxed at Wrigley Field,  but his splits are oddly reversed. On the road he allows just a .214 batting average and a 1.14 WHIP. But at home with the fans rooting for him it explodes to a .320 average and a 1.59 WHIP.

And this Cubs team struggles without rest. They are 37-48 on back-to-backs vs. 10-3 when they get a break.

BET CARDINALS (-145).

Run line/Against the spread

St. Louis’s ATS record has been dependent on whether they are the favorite or the underdog. As an underdog, St. Louis is 29-13 ATS, which is 4th-best in MLB. But as a as a favorite that record is 21-36. And against the NL Central the Cardinals are 11-17.

The Cubs aren’t much better with their 12-14 record ATS. Plus they have lost 20 straight games without covering, so I will PASS.

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Over/Under

While the Cardinals trend toward the Over this season (49-46-4), its almost all thanks to their home games (28-17-1). On the road they have the 4th-best Under record in MLB (28-21-2).

And in the last 3 games the Cardinals and Cubs have averaged the 4th (9.33) and 5th (8.67) most hits per game. I expect a regression to come today.

LEAN UNDER (+100).

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St. Louis Cardinals at Chicago Cubs odds, picks and predictions

Analyzing Thursday’s St. Louis Cardinals at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

The St. Louis Cardinals (43-53) visit the Chicago Cubs (45-50) on Thursday to kick off a 4-game series against their NL Central Division rival. First pitch from Wrigley Field is set for 8:05 p.m. ET (ESPN+). Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Cardinals lead 3-2

St. Louis won 6-4 as -107 home favorites Wednesday to complete a 3-game  sweep of the Miami Marlins. The Cardinals are on a 5-game win streak and sit at 21-27 on the road. St. Louis is 2 1/2 games behind the Cubs for 3rd place in the division.

Chicago beat the Washington Nationals 8-3 Wednesday as -146 home favorites to win the series 2-1. The game was tied at 3 when the Cubs scored 5 runs in the bottom of the 8th inning. The Cubs have won back-to-back games, but are only 5-5 in their last 10. Chicago is 24-25 at home on the year.

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Cardinals at Cubs projected starters

LHP Steven Matz vs. RHP Marcus Stroman

Matz (0-7, 4.86 ERA) makes his 13th start. He has a 1.51 WHIP, 3.3 BB/9 and 8.6 K/9 in 76 innings.

  • Last outing: No-decision, 4 1/3 IP, 4 ER, 4 H, 3 BB, 4 K in a 9-6 home win Saturday vs. the Washington Nationals
  • Career vs. Chicago (regular season): 0-2, 3.92 ERA (20 2/3 IP, 9 ER), 22 H, 7 BB, 20 K in 4 appearances (3 starts)

Stroman (10-6, 2.88 ERA) makes his 21st start. He has a 1.09 WHIP, 3.2 BB/9 and 7.7 K/9 in 118 2/3 innings.

  • Last outing: Win, 6 IP, 1 ER, 3 H, 1 BB, 3 K in a 10-4 home win Saturday vs. the Boston Red Sox
  • Career vs. St. Louis: 1-5, 4.96 ERA (49 IP, 27 ER), 61 H, 1.43 WHIP, 8.8 K/9 in 9 starts

Cardinals at Cubs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:28 a.m. ET.

  • Moneyline (ML): Cardinals +110 (bet $100 to win $110) | Cubs -130 (bet $135 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-190) | Cubs -1.5 (+155)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

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Cardinals at Cubs picks and predictions

Prediction

Cardinals 6, Cubs 4

Moneyline

BET CARDINALS (+110).

The Cardinals are 7-3 in the last 10 meetings and are the hotter team — on a 5-game win streak and 8-2 in their last 10. The Cubs are only 2-3 in Stroman’s last 5 starts and 0-3 in his last 3 starts vs. St. Louis. While Matz is 0-7, the Cardinals are 3-2 in his last 5 starts.

Run line/Against the spread

PASS.

St. Louis should cover here but at +1.5 (-190) the line is not worth the juice, bet on the moneyline and/or O/U instead.

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Over/Under

LEAN OVER 8.5 (-110).

The Over is 5-1 in the Cardinals’ last 6 games and 2-1 in Matz’s last 3 starts while the Over is 9-1 in the Cubs’ last 10 games inclduing 8 straight. Also, the Over is also 2-0 in Stroman’s last 2 starts.

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St. Louis Cardinals at Chicago Cubs odds, picks and predictions

Analyzing Wednesday’s St. Louis Cardinals at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

The St. Louis Cardinals (13-24) finish their 3-game road series with the Chicago Cubs (17-19) Wednesday. First pitch from Wrigley Field is at 7:40 ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Cardinals lead 2-0

The Cardinals may be pessimistic on how this season will play out after one of the slowest starts in franchise history but their rivalry with the Chicago Cubs is still as powerful as ever. St. Louis has come out of the gate running against its NL Central rival and can try to complete its first series sweep of the season with a win Wednesday.

The Cubs are still trying to figure themselves out. They have the 5th best batting average in the league (.255) but are only 10th in runs/game due to having a league-worst 273 runners left on base.

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Cardinals at Cubs projected starters

LHP Jordan Montgomery vs. LHP Justin Steele

Montgomery (2-4, 3.29 ERA) makes his 8th start. He has a 1.22 WHIP, 2.0 BB/9 and 8.3 K/9 through 41 IP.

  • Last start: No decision, 6 IP, 2 ER, 6 H, 1 B, 6 K vs. Detroit Tigers on Friday
  • 0.46 ERA in 3 road starts this season

Steele (5-0, 1.45 ERA) makes his 8th start. He has a 0.95 WHIP, 2.3 BB/9 and 7.5 K/9 through 43 1/3 IP.

  • Last start: Win, 7 IP, 1 ER, 6 H, 0 BB, 4 K vs. Miami Marlins on Friday
  • .153 opponent batting average (OBA) when they take the first pitch but  .289 OBA when they swing

Cardinals at Cubs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:07 a.m. ET.

  • Moneyline (ML): Cardinals -110 (bet $110 to win $100) | Cubs -110 (bet $110 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals -1.5 (+155) | Cubs +1.5 (-190)
  • Over/Under (O/U): 7.5 (O: -105 | U: -115)

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Cardinals at Cubs picks and predictions

Prediction

Cubs 7, Cardinals 5

Moneyline

Montgomery’s road splits are intimidating but the Cardinals, despite their success in games 1 and 2, still sport a 39% win percentage on the road and are just 4-8 after a win. It’s never easy to complete a sweep so I will take the CUBS (-110) to salvage a win Wednesday.

Run line/Against the spread

St. Louis has the 3rd worst cover percentage this season and picking the Cubs +1.5 (-190) is too chalky. It’s best to PASS on the run line and focus on the moneyline.

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Over/Under

The Cubs are not great at bringing their runners in as previously noted, but the Cardinals are nearly just as bad. Chicago has a league-worst 273 runners left on base, while St. Louis is the 2nd worst with 268 stranded. However, both teams are top 10 in batting average and just need a spark and some luck to break their way to get those runners to score.

Trends also point to a high-scoring affair Wednesday. The Cubs are 4-1 to the Over in their past 5 NL Central contests and the Cardinals have gone over in 6 of their last 7 outings overall.

BET OVER 7.5 (-105).

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St. Louis Cardinals at Chicago Cubs odds, picks and predictions

Analyzing Tuesday’s St. Louis Cardinals at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

The St. Louis Cardinals (12-24) and Chicago Cubs (17-18) clash Tuesday in the 2nd game of a 3-game set at Wrigley Field. First pitch is slated for 7:40 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Cardinals vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: Cardinals lead 1-0

St. Louis went into this series with its worst 35-game record since 1973. But the Redbirds got solid pitching in taking Monday’s 3-1 victory in the series opener and have now won 2 in a row.

The Cubs have lost 5 in a row to their rivals from Missouri dating back to last season. Chicago went 1-for-7 with runners in scoring position Monday. The Cubs are 2-5 and have hit just .181 with runners in scoring position over their last 7 games.

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Cardinals at Cubs projected starters

RHP Jack Flaherty vs. RHP Jameson Taillon

Flaherty (2-4, 6.29 ERA) makes his 8th start of the season. He has a 1.63 WHIP, 5.8 BB/9 and 9.4 K/9 through 34 1/3 IP.

  • Lit up for 10 runs in 2 1/3 IP against the Los Angeles Angels Thursday
  • Has allowed 4 ER or more in 3 of his last 4 starts
  • Got the green light to start after being struck in the hand by a comebacker last time out
  • Has held current Cubs batters to an aggregate .528 OPS

Taillon (0-2, 5.29 ERA) is making his 5th start. He has registered a 1.29 WHIP, 2.1 BB/9 and 10.6 K/9 through 17 IP.

  • Has battled through a .347 batting average on balls in play and a 53.4% left-on-base rate
  • Has allowed 7 ER in 9 IP across 2 starts at Wrigley Field this season
  • Has struggled against left-handed batters in 2023 (.872 OPS allowed)

Cardinals at Cubs odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 11:40 a.m. ET.

  • Moneyline: Cardinals +110 (bet $100 to win $110) | Cubs -130 (bet $130 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-200) | Cubs -1.5 (+164)
  • Over/Under (O/U): 8 (O: -104 | U: -118)

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Cardinals at Cubs picks and predictions

Prediction

Cubs 4, Cardinals 3

Moneyline

The runs scored/runs allowed numbers for both teams indicate that they are both below their “should-be” records. For example, the Cubs have scored 169 while allowing 125 and yet are under-.500.

The Redbirds had been just 2-8 over their last 10 road games prior to Monday’s contest. Recent Cubs missteps have been driven by not-so-predictable shortcomings in clutch hitting.

Look for Taillon and a fresher Chicago bullpen to give the Cubs more of a 60% chance to win this one. There is value in CHICAGO (-130).

Run line/Against the spread

An inward breeze is expected at Wrigley, and this game is likely to be a relatively low-scoring affair. That increases the risk of siding with the Cubs by margin. PASS.

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Over/Under

There is enough play to starter, bullpen and batting numbers — on both sides — that the middle is the place to be. STEER CLEAR.

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St. Louis Cardinals at Chicago Cubs odds, picks and predictions

Analyzing Monday’s St. Louis Cardinals at Chicago Cubs odds and lines, with MLB expert picks, predictions and best bets.

The St. Louis Cardinals (11-24) and Chicago Cubs (17-17) renew their rivalry in the opener of a 3-game set at Wrigley Field Monday. First pitch is at 7:40 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Cardinals vs. Cubs odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting. Cardinals won 13-6 last year.

The Cardinals snapped an 8-game losing streak with a 12-6 win over the Detroit Tigers Sunday. They tried to give it away though, as the bullpen came in and allowed 5 runs in the 6th inning to put Detroit up 6-3. 1B Paul Goldschmidt had other ideas as he went 4-for-5 with 3 homers and 4 RBI.

The Cubs have stumbled after a hot start to the season, losers of 7 of their last 10 games. They dropped the final game against the Miami Marlins Sunday, losing 5-4 in 14 innings. Their last 10 games were against the Marlins and Washington Nationals – 2 teams not expected to be in it. Chicago is 10-9 at home this season.

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Cardinals at Cubs projected starters

RHP Miles Mikolas vs. RHP Marcus Stroman

Mikolas (1-1, 5.79 ERA) makes his 8th start. He has a 1.66 WHIP, 2.2 BB/9 and 8.2 K/9 in 37 1/3 IP.

  • Last start Wednesday vs. Los Angeles Angels: 5 2/3 IP, 3 ER, 8 H, 0 BB, 5 K
  • Last 5 starts vs. Cubs: 2-1, 3.09 ERA, 1.09 WHIP, 25 K in 32 IP

Stroman (2-2, 2.18 ERA) makes his 8th start. He has a 1.09 WHIP, 3.5 BB/9 and 8.3 K/9 in 41 1/3 IP.

  • Last start Wednesday vs. Washington Nationals: 6 IP, 1 ER, 5 H, 3 BB, 5 K
  • Last 5 starts vs. Cardinals: 0-2, 5.97 ERA, 1.36 WHIP, 27 K in 28 2/3 IP

Cardinals at Cubs odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:36 a.m. ET.

  • Moneyline (ML): Cardinals +115 (bet $100 to win $115) | Cubs -140 (bet $140 to win $100)
  • Run line (RL)/Against the spread (ATS): Cardinals +1.5 (-190) | Cubs -1.5 (+155)
  • Over/Under (O/U): 7 (O: -110 | U: -110)

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Cardinals at Cubs picks and predictions

Prediction

Cubs 4, Cardinals 2

Moneyline

The Cubs have beaten the Cards just twice in the last 10 games. Stroman has an ERA near 6 against the Cards, and Mikolas has been solid, right? Well, if you look deeper, Stroman’s numbers are skewed from a 9 ER outing last year. Take that away, and his ERA in the other 4 contests is 3.65. Also, Mikolas’ last 2 starts at Wrigley haven’t been good, allowing a combined 7 ER in 11 2/3 IP. I’m siding with the Cubs but not at -140.

PASS and look to the spread.

Run line/Against the spread

There has been just one 1-run game between the teams in the last 9. The Cards are 13-22 on the RL and 7-9 RL on the road. Meanwhile, the Cubs are 20-14 RL and 11-8 RL at home. Just 7 of the Cards’ 24 losses have been by 1 run.

Take the CUBS -1.5 (+155).

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Over/Under

It’s slated to be 51 degrees with a 14-mph wind blowing in from left-center field. That means it’ll be difficult for balls to leave the yard. The Cubs are 2-8 O/U over the last 10, and the Cards are 6-4. The Under is 5-4-1 in the last 10 meetings between the teams.

With the weather and struggling bats, take the UNDER 7 (-110).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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