Seahawks open as double-digit underdogs vs. 49ers for wild card game

Their reward is facing the toughest defense to come along in several years.

The Seahawks finished their season strong and got a little bit lucky last night, clinching a playoff berth thanks to the Lions defying recent history and upsetting the Packers in Green Bay. Thanks to that and their own win over the Rams Seattle has snuck into the playoffs, clinching the NFC’s last seed.

Their reward is facing the toughest defense to come along in several years – one that has already embarrassed them twice this season. On Saturday afternoon, the Seahawks will travel to Santa Clara and face the freight train 49ers, who have won 10 straight games going into the postseason.

According to USA TODAY Sports Data, the Niners are favored by 10 points. The over/under is set at 43.5 points and the money line is San Francisco -550 and Seattle +425.

The NFL tends to schedule their least-compelling playoff matchup in the Saturday afternoon timeslot, usually reserved for whoever crawls out of the AFC South. That the Seahawks are competing in that spot is a reflection on what the league thinks of their chances.

Kickoff is 1:30 p.m. Pacific Time.

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Seahawks-49ers odds: Undefeated San Francisco favored over Seattle

Previewing Monday Night Football’s Seattle Seahawks at San Francisco 49ers betting odds and lines, with NFL Week 10 matchup analysis, picks and tips.

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The undefeated San Francisco 49ers (8-0) will host the rising Seattle Seahawks (7-2) Monday night at Levi’s Stadium for an 8:15 p.m. ET kickoff. We analyze the Seahawks-49ers odds and lines while providing betting tips and advice around this key Week 10 NFL matchup.

Seahawks at 49ers: Week 10 preview, betting trends and notes


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  • Seattle has won five of its last six games but has gone just 3-3 against the spread in that span.
  • The 49ers are 5-3 ATS this season but didn’t cover the spread in two of their last three games.
  • The Seahawks have won nine of their last 10 games against the 49ers, going 7-3 ATS in those meetings. Their average margin of victory is 11.8 points per game.
  • The 49ers are 13-2 ATS in their last 15 Monday Night Football games.
  • Seattle is 0-5 ATS after covering the spread the week before.
  • The total has gone Over in six of Seattle’s last seven games against the NFC West.
  • The 49ers rank second in the NFL in rushing yards, time of possession and plays run per game.

Seahawks at 49ers: Key injuries

WR Josh Gordon could make his Seahawks debut Monday night after being claimed by Seattle off waivers from the New England Patriots; he’s recovering from a knee injury. S Quandre Diggs‘ (hamstring) status for Monday is uncertain.

49ers K Robbie Gould (quad) is doubtful. TE George Kittle (knee) is questionable.

Seahawks at 49ers: Odds, betting lines and prediction

Odds via BetMGM; access USA TODAY Sports’ betting odds for a full list. Lines last updated Friday at 2 p.m. ET.

Prediction

Seahawks 23, 49ers 21

Moneyline (?)

The Seahawks are one of the best teams in the league and this is a game ripe for an upset. As good as the 49ers have been this year, they showed a few flaws against Arizona last week against dual-threat quarterback Kyler Murray.

Russell Wilson is having an MVP season and will lift the Seahawks to victory. Bet SEATTLE to win straight up with the moneyline (+220).

Against the Spread (?)

If we’re picking the Seahawks to win straight up, you bet we’re taking them with the points, too. Seattle is a 6.5-point underdog in Week 10, which is a huge spread for a divisional matchup – even if San Francisco is at home.

Happily take the points and take the SEAHAWKS (-110) to cover the 6.5-point margin. They’re 13-3 ATS in their last 16 against the 49ers.

Over/Under (?)

The Over/Under is a tough pick this week, since the total is just 46.5 points. The Seahawks offense can go on a tear at any moment thanks to Wilson, but San Francisco’s defense is dominant.

This should be a fairly low-scoring affair with both teams managing the clock. Bet the UNDER (-110) Monday night.

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