San Francisco Giants at Chicago White Sox odds, picks and predictions

Analyzing Thursday’s San Francisco Giants at Chicago White Sox odds and lines, with expert MLB picks, predictions and best bets.

The San Francisco Giants (2-3) and the Chicago White Sox (3-3) wrap up a 3-game series Thursday. First pitch at Guaranteed Rate Field is scheduled for 2:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. White Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Series tied 1-1 in 2023. White Sox won the series 3-0 in 2022.

The Giants won the interleague series opener Monday 12-3 — an early-season high in runs. San Francisco suffered a 7-3 loss in Game 2 on Wednesday to even up the series, although the Over (7.5) cashed for a 2nd consecutive contest. San Francisco has alternated losses and wins in each of its 5 outings.

The White Sox have scored 3 or more runs in each of their 6 games while yielding 3 or more runs in each of the past 5 contests. The Over has cashed in Chicago’s last 5 contests after an Under result on Opening Day last Thursday.

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Giants at White Sox projected starters

LHP Alex Wood vs. RHP Lance Lynn

Wood went 8-12 with a 5.10 ERA in 2022. He had a 1.24 WHIP, 2.1 BB/9 and 9.0 K/9 in 130 2/3 IP across 26 starts.

  • Recorded a 5-7 record and 5.51 ERA with 12 HR and a .247 opponent batting average (OBA) across 67 IP in 14 road starts last season.
  • Went 2-2 with a 5.95 ERA and 3 HR with 1 BB and 20 K across 19 2/3 IP in 4 interleague starts in ’22.

Lynn (0-0, 3.18) makes his 2nd start of the season. He allowed 2 ER on 3 H and 4 BB with 6 K across 5 2/3 IP in a 96-pitch debut Friday at the Houston Astros.

  • Posted a 4-3 record, 4.05 ERA and .232 OBA with 9 HR allowed across 53 1/3 IP in 9 home starts in 2022.
  • Allowed just 3 H and 2 BB with 5 K across 6 scoreless innings in a no-decision July 1 at San Francisco last season.

Giants at White Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:44 a.m. ET.

  • Moneyline (ML): Giants +110 (bet $100 to win $110) | White Sox -135 (bet $135 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-185) | White Sox -1.5 (+150)
  • Over/Under (O/U): 7.5 (O: -115 | U: -105)

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Giants at White Sox picks and predictions

Prediction

Giants 6, White Sox 3

Moneyline

The GIANTS (+110) are a solid play on the road on getaway day Thursday.

The Giants are 5-1 in the past 6 games in Game 3 of a series and 12-5 in the past 17 games against a right-handed starting pitcher dating back to last season.

The White Sox are just 3-9 in the past 12 games at home dating back to last season and have cashed just once in the past 5 interleague games against a left-handed pitcher.

Run line/Against the spread

The Giants +1.5 (-185) are just a little too expensive in the event you need a little insurance and can’t bring yourself to play San Francisco straight up.

Chicago has dropped 3 of the past 5 games, and it has lost each of the contests by 2 or more runs.

PASS.

Over/Under

OVER 7.5 (-115) is worth a look in this interleague series finale.

The Over has cashed in 5 straight games for the White Sox and is 3-1 in the past 4 games for the Giants. San Francisco has cashed the Over in 9 of the past 12 games against right-handed starting pitchers dating back to last season, too.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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