First look: San Francisco 49ers at Philadelphia Eagles odds and lines

Looking at Sunday’s San Francisco 49ers at Philadelphia Eagles NFC title game odds, lines and trends. Here’s what you need to know.

The San Francisco 49ers (15-4) visit the Philadelphia Eagles (15-3) in the NFC Championship Game Sunday. Kickoff from Lincoln Financial Field is set for 3 p.m. ET (FOX). Below, we look at 49ers vs. Eagles odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The 49ers won their 12th consecutive game Sunday, beating the Dallas Cowboys 19-12 in the Divisional Round. Second-seeded San Francisco, which was a 3.5-point home favorite, was able to pull out the victory and rookie QB Brock Purdy improved to 7-0 as a starter. The win marked the 2nd season in a row that San Francisco beat Dallas in the playoffs.

The Eagles are coming off a 38-7 Divisional Round blowout win as 8-point home favorites vs. the New York Giants Saturday in a game many expected to be close. The Eagles, who had the advantage of a bye the previous week as the No. 1 seed, jumped out to a 14-0 lead after the opening quarter and led 28-0 at the half. Philadelphia finished with 416 total yards, while holding New York to 227. Philly won the turnover battle (1-0), had double the 1st downs (26-13) and led time of possession (35:43 to 24:17).

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49ers at Eagles odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 4:26 a.m. ET.

  • Moneyline (ML): 49ers +145 (bet $100 to win $145) | Eagles -125 (bet $125 to win $100)
  • Against the spread (ATS): 49ers +2.5 (-105) | Eagles -2.5 (-115)
  • Over/Under (O/U): 45.5 (O: -108 | U: -112)

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2022 betting stats (including postseason)

  • ML: 49ers 15-4 | Eagles 15-3
  • ATS: 49ers 13-6 | Eagles 9-9
  • O/U: 49ers 10-9 | Eagles 10-8

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49ers vs. Eagles head-to-head

Sunday will mark the 36th meeting between these franchises. The 49ers lead the all-time series 20-14-1, including a 14-0 shutout at home in a 1996 NFC Wild Card Game — the only time these 2 met in the postseason.

Philly won 5 straight vs. San Francisco from 2005-10, but San Francisco leads the series 3-2 since. They last met in Week 2 of 2021 with the 49ers winning 17-11 as 3-road favorites.

Purdy has never faced the Eagles, while Philly QB Jalen Hurts is 0-1 as a starter vs. the 49ers. Hurts threw for 190 yards (12 of 23 attempts) with no TDs or INTs in the 2021 contest and played sparingly against the 49ers in 2020 — his rookie season — with just 3 carries and no pass attempts.

See also: AFC Championship first look: Bengals at Chiefs odds and lines

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First look: San Francisco 49ers at Philadelphia Eagles odds and lines

Looking at Sunday’s San Francisco 49ers at Philadelphia Eagles Week 2 NFL odds, lines and trends. Here’s what you need to know.

The San Francisco 49ers (1-0) and Philadephia Eagles (1-0) have a Week 2 meeting Sunday in Philadelphia. Kickoff from Lincoln Financial Field is set for 1 p.m. ET. Below, we look at the 49ers vs. Eagles odds and lines; check back for our NFL picks and predictions.

Also see: All Week 2 odds and lines

The 49ers opened their season with a commanding 41-33 victory at the Detroit Lions, but a 16-point quarter from the home side resulted in a backdoor over of the 9.5-point spread. QB Jimmy Garoppolo was 17-for-25 for 314 yards with 1 TD and rookie QB Trey Lance completed his only pass for a 5-yard TD.

WR Deebo Samuel led the way with 9 receptions on 12 targets for 189 yards and a score, while rookie RB Elijah Mitchell fronted the ground attack after starter Raheem Mostert was forced to exit the game with an injury. Mitchell racked up 104 yards on 19 carries and added a rushing TD. The game cleared the 46-point projected total in the third quarter.

The Eagles opened their season with a 32-6 victory as 3-point underdogs at the Atlanta Falcons. QB Jalen Hurts threw for 264 yards and 3 TD on 27-for-35 passing and added 62 rushing yards on 7 carries. First-round draft pick WR DeVonta Smith led the receiving corps with 71 yards on 6 receptions from 8 targets.

Philadelphia kept Atlanta in check by limiting QB Matt Ryan to 164 passing yards and starting RB Mike Davis to 49 yards on 15 carries as the game finished 11 points shy of the posted total of 49.

49ers at Eagles odds, spread and line

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 5:30 p.m. ET.

  • Money line: 49ers -200 (bet $200 to win $100) | Eagles +160 (bet $100 to win $160)
  • Against the spread (ATS): 49ers -3.5, -115 (bet $115 to win $100) | Eagles +3.5, -107 (bet $107 to win $100)
  • Total (O/U): 50.5, Over -105 (bet $105 to win $100) | Under -115 (bet $115 to win $100)

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2021 betting stats:

  • ML: 49ers 1-0 | Eagles 1-0
  • ATS: 49ers 0-1 | Eagles 1-0
  • O/U: 49ers 1-0 | Eagles 0-1

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49ers at Eagles head-to-head

The 49ers and Eagles have met just once since 2017.

Philadelphia picked up a 25-20 victory as an 8.5-point road underdog in Week 4 last season while the total stayed 1 point Under the number.

However, there has been significant changes to both rosters since that game as Garoppolo was sidelined for the 49ers in last season’s meeting and then-Eagles QB Carson Wentz has left.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.

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