The San Francisco 49ers and the Chicago Bears meet in Week 1 action with kickoff from Soldier Field on Sunday, Sept. 11, set for 1 p.m. ET (FOX). Below, we analyze Tipico Sportsbook‘s lines around the 49ers vs. Bears odds and lines; check back for our NFL picks and predictions.
A new era is set to officially begin for the visiting 49ers as last year’s 3rd-overall draft pick, Trey Lance, is set to take over at quarterback. San Francisco enters the season with lofty expectations and with the 2nd-best odds to win the NFC West behind only the defending champion Los Angeles Rams.
San Francisco finished the preseason 2-1 after falling 17-0 at the Houston Texans in their final appearance. Lance led 3 scoreless drives.
Also see: All Week 1 odds and lines
Chicago opens up on the absolute opposite end of the spectrum. The Bears have the worst odds to win the division in the NFC North and are amongst the longest odds in the league to win the Super Bowl. QB Justin Fields enters his 2nd season with what appears to be a weak supporting cast and will have an uphill battle to lead this team to many victories.
The Bears wrapped up a 3-0 preseason with a 21-20 squeaker at the Cleveland Browns. Fields notched 3 first-half TDs and finished 14-of-16 for 156 yards.
Play our free daily Pick’em Challenge and win! Play now!
49ers at Bears odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Sunday, Aug. 28, at 7:01 p.m. ET.
- Money line (ML): 49ers -350 (bet $350 to win $100) | Bears +265 (bet $100 to win $265)
- Against the spread (ATS): 49ers -7.5 (+102) | Bears +7.5 (-125)
- Over/Under (O/U): 41.5 (O: -110 | U: -110)
[the_huddle]
2021 betting stats (including postseason):
- ML: 49ers 12-8 | Bears 6-11
- ATS: 49ers 12-8 | Bears 6-11
- O/U: 49ers 8-12 | Bears 7-10
Exclusive USA TODAY Network offer: Deposit $10 or more, get $200 in instant bet credits at Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Place your legal, online sports bets at Tipico. Let’s make this interesting. Bet now!
49ers vs. Bears head-to-head
The 49ers lead the all-time series 35-32-1, including 3-0 in postseason play.
The 49ers have won 5 of the last 9 meetings vs. the Bears since 2006 — both straight-up and ATS. The Over has hit in 5 of 9 meetings, too.
The squads have met once with either QB under center, a 33-22 San Francisco road win and cover in Week 8 with Fields starting for the Bears. However, QB Jimmy Garoppolo played for the 49ers in that meeting.
Bet legally online with a trusted partner: Tipico Sportsbook, Sportsbook Wire’s official sportsbook partner in CO and NJ. Bet now!
If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.
Follow Andrew Reid on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.
Access more NFL coverage:
BetFTW | TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWire | TitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire
Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO).
[lawrence-newsletter]
[lawrence-auto-related count=3 category=1367]
