San Diego Padres at Boston Red Sox odds, picks and predictions

Analyzing Saturday’s San Diego Padres at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The San Diego Padres (45-41) and Boston Red Sox (43-38) face off in Game 2 of a 3-game series Saturday. First pitch from Fenway Park is set for 4:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Padres vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: San Diego leads 1-0

San Diego routed Boston 9-2 in Friday’s series opener while covering as a +139 road underdog. The Padres scored all 9 of their runs in the 5th inning after being down 1-0 entering the inning. San Diego has won 4 straight.

RHP Nick Pivetta picked up the loss, pitching 4 innings while allowing 5 ER, 7 H and 1 BB with 4 K. The Red Sox have lost back-to-back games.

Padres at Red Sox projected starters

RHP Michael King vs. RHP Tanner Houck

King (5-5, 3.75 ERA) makes his 17th start and 18th appearance. He has a 1.29 WHIP, 3.7 BB/9 and 10.5 K/9 through 93 2/3 innings.

  • Last start: Loss, 6 IP, 5 ER, 9 H, 1 BB, 8 K in a 6-2 loss vs. Milwaukee Sunday
  • Career vs. Boston: 2-4, 5.20 ERA (27 2/3 IP, 16 ER), 28 H, 8 BB, 29 K across 2 starts and 10 relief appearances

Houck (7-5, 2.18 ERA) makes his 17th start. He has a 0.97 WHIP, 1.6 BB/9 and 8.8 K/9 through 103 1/3 innings.

  • Last start: No-decision, 6 2/3 IP, 2 ER, 5 H, 1 BB, 7 K in a 7-6 win over Toronto Monday
  • Leads league with 2.18 ERA
  • First career start vs. San Diego

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Padres at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:40 a.m. ET.

  • Moneyline (ML): Padres +115 (bet $100 to win $115) | Red Sox -135 (bet $135 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres +1.5 (-175) | Red Sox -1.5 (+145)
  • Over/Under (O/U): 8.5 (O: -115 | U: -105)

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Padres at Red Sox picks and predictions

Prediction

Padres 6, Red Sox 4

Moneyline

LEAN PADRES (+115). 

San Diego has won 4-straight and is 2-0 in its last 2 on the road while Boston has dropped back-to-back home games. The Padres are also 8-2 in their last 10 overall.

This is a very slight lean as Boston is 7-3 in its last 10 overall and 6-4 in its last 10 vs. San Diego.

Run line/Against the spread

PASS. 

I like the Padres to cover here as they are 44-42 ATS this season while the Red Sox are only 36-45 ATS on the year, but they are not worth the risk of betting on as +1.5 (-160) underdogs. Bet on the moneyline and/or total instead.

Over/Under

BET OVER 8.5 (-115). 

The Over has hit in each of Boston’s last 4 games and is 7-3 in its last 10 overall, also hitting in 4 consecutive home games for the Red Sox. For San Diego, the Over has hit in each of its last 8 games.

Be aware that the Under is 6-3-1 in the last 10 San Diego-Boston matchups.

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San Diego Padres at Boston Red Sox odds, picks and predictions

Analyzing Friday’s San Diego Padres at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Boston Red Sox (43-37) welcome the San Diego Padres (44-41) to Fenway Park Friday for the opener of a 3-game series. First pitch is set for 7:10 p.m. ET (Apple TV+). Let’s analyze FanDuel Sportsbook’s lines around the Padres vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series:  First meeting; Boston won 2-1 in 2023

The Red Sox, who are 19-21 at home this season, split a 2-game series with the Toronto Blue Jays, closing with a 9-4 home loss on Tuesday. It has been on fire as of late, winning 8 of its last 10 games and is 5-2 in its last 7 at home. The Red Sox are 16-12 against NL teams this season.

The Padres are 20-19 away and are 1 of just 11 teams with a road record over .500. San Diego has won 3 straight games and 7 of its last 8. It is coming off an 8-5 victory Wednesday over the Washington Nationals to complete a 3-game sweep. San Diego is 42-42 against the spread (ATS).

Padres at Red Sox projected starters

RHP Randy Vasquez vs. RHP Nick Pivetta

Vasquez (2-4, 5.10 ERA) makes his 11th start. He has a 1.68 WHIP, 2.3 BB/9 and 5.9 K/9 in 47 2/3 IP.

  • Last start: Win, 5 IP, 0 ER, 5 H, 3 BB, 3 K in 6-4 home win over the Milwaukee Brewers Saturday
  • 2024 road splits: 1-2, 6.85 ERA (22 1/3 IP, 17 ER), 1.88 WHIP, 6 HR, 6.9 K/9 in 5 starts
  • Career vs. Red Sox: 0-0, 4.91 ERA (3 2/3 IP, 2 ER), 1. WHIP, 7.4 K/9 in 1 start

Pivetta (4-4, 4.06 ERA) makes his 12th start. He has a 1.16 WHIP, 2.3 BB/9 and 10.0 K/9 in 57 2/3 IP.

  • Last start: No-decision, 4 1/3 IP, 3 ER, 6 H, 1 BB, 5 K in 4-3 road win over the Cincinnati Reds Saturday
  • 2024 home splits: 1-2, 4.62 ERA (25 1/3 IP, 13 ER), 1.26 WHIP, 3 HR, 11.7 K/9 in 5 starts
  • Career vs. Padres: 0-3, 5.57 ERA (21 IP, 13 ER), 1.29 WHIP, 14.1 K/9 in 5 appearances (3 starts)

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Padres at Red Sox odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:46 a.m. ET.

  • Moneyline (ML): Padres +134 (bet $100 to win $134) | Red Sox -158 (bet $158 to win $100)
  • Run line (RL)/Against the spread (ATS): Padres +1.5 (-154) | Red Sox -1.5 (+128)
  • Over/Under (O/U): 9.5 (O: -108 | U: -112)

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Padres at Red Sox picks and predictions

Prediction

Red Sox 6, Padres 4

Moneyline

BET RED SOX (-158).

The Red Sox have been on fire as of late and have won 4 straight starts by Pivetta and have won 6 of his last 8 starts. Boston is 5-3 in its last 8 home games and won 2 of 3 in Fenway against the New York Yankees and Philadelphia Phillies among its last 3 home series.

While the Padres have won 7 of their last 8 games, they are just 1-9 in their last 10 road games. San Diego is 3-7 in Vasquez’s starts this season as well. Considering those trends, despite the juice, take RED SOX (-158).

Run line/Against the spread

PASS.

The Padres have strung together wins as of late, so they should be able to keep this game close. Despite consistently winning when Pivetta starts, Boston has won by a single run in 3 of the team’s 7 victories with him on the mound.

Avoid the moneyline and back the suggested moneyline play.

Over/Under

BET OVER 9.5 (-108).

The Padres have gone Over in 7 straight games and have scored at least 7 runs in 3 straight games. They are 45-38-1 O/U on the season and have gone Over in Vasquez’s last 2 starts.

The Red Sox have gone Over in 3 straight and are 7-3 O/U in their last 10. Boston has scored at least 4 in 9 of its last 10 and at least 7 in 6 of those. Considering those trends, back OVER 9.5 (-108).

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow @nathanbeighle_ on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Fantasy baseball help from BaseballHQ.com:
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