First look: Notre Dame Fighting Irish at Clemson Tigers odds and lines

Looking at Saturday’s Notre Dame Fighting Irish at Clemson Tigers college football odds, lines and trends. Here’s what you need to know.

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The Notre Dame Fighting Irish (7-2) visit the Clemson Tigers (4-4) on Saturday. Kickoff from Memorial Stadium is set for noon ET (NBC). Below, we look at Notre Dame vs. Clemson odds from BetMGM Sportsbook. Also see: SportsbookWire’s college football picks and predictions.

Notre Dame throttled Pitt 58-7 on Saturday covering as a 21-point home favorite. QB Sam Hartman went 18 of 25 for 288 yards and 2 INTs while QB Steve Angeli went 6 of 7 for 92 yards and a TD. The Fighting Irish scored in a multitude of ways with a passing TD, 4 rushing TDs, a Pick Six, and a punt return TD.

Clemson fell 24-17 against North Carolina State on Saturday but covered as a 9.5-point road underdog. QB Cade Klubnik went 33 of 50 for 263 yards and 2 INT and RB Phil Mafah carried the ball 16 times for 84 yards and 2 TDs in the loss.

Notre Dame is No. 12 in the US LBM Coaches Poll powered by USA TODAY Sports

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Notre Dame at Clemson odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 10:42 a.m. ET,

  • Moneyline (ML): Notre Dame -150 (bet $150 to win $100) | Clemson +120 (bet $100 to win $120)
  • Against the spread (ATS): Notre Dame -2.5 (-110) | Clemson +2.5 (-110)
  • Over/Under (O/U): 46 (O: -110 | U: -110)

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2023 betting stats

  • ML: Notre Dame 7-2 | Clemson 4-4
  • ATS: Notre Dame 7-2 | Clemson 2-6
  • O/U: Notre Dame 5-4 | Clemson 3-5

Notre Dame vs. Clemson head-to-head

Notre Dame last faced Clemson in November of 2022 when it won 35-14 to cover as a 4-point home underdog. The Over of 43.5 hit in that game.

These programs have faced off 5 times since 2015 with Clemson going 3-2 in that span. Notre Dame is 3-2 ATS in the matchups while the Over is 2-3. Notre Dame covered as the underdog in each of its 2 series wins while Clemson covered as a double-digit favorite in each of its 3 series wins.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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