The 5 best NFL prop bets for Week 16

The five best NFL player prop bets to make for the upcoming week.

As we hit the Christmas weekend, most of the games will be played on Saturday, forcing teams into short weeks of preparation. This week, we pick one of the hottest fantasy players in the league to score a touchdown (again), a Pro Bowl quarterback not to hit the Over a high number despite two huge weeks, and a running back, wide receiver and tight end to all go Over their respective O/U numbers.

Odds provided by Tipico Sportsbook

Vegas odds chart for daily fantasy football play: Week 16

A snapshot look at the NFL betting lines and odds for Week 16 sports betting and DFS action.

A good way to start your weekly homework for DFS (daily fantasy sports) play is to analyze the early Vegas odds around Week 16.

These guys have a long history of making money off of setting the right game spread and points scored. So it can be an early indicator of teams to target due to high-scoring potential, and teams to avoid for the opposite reason.

Odds provided by Tipico Sportsbook

NFL Odds: Week 16

Day Time (ET) Away Home Away odds Home Odds Total points O/U
Saturday, Dec. 24 1:00 PM Detroit Lions Carolina Panthers -2.5 +2.5 43.5
Saturday, Dec. 24 1:00 PM New York Giants Minnesota Vikings +4 -4 48.5
Saturday, Dec. 24 1:00 PM Buffalo Bills Chicago Bears -8.5 +8.5 40.0
Saturday, Dec. 24 1:00 PM Atlanta Falcons Baltimore Ravens +6 -6 35.5
Saturday, Dec. 24 1:00 PM Seattle Seahawks Kansas City Chiefs +10 -10 49.5
Saturday, Dec. 24 1:00 PM Houston Texans Tennessee Titans +3.5 -3.5 35.5
Saturday, Dec. 24 1:00 PM New Orleans Saints Cleveland Browns +3 -3 32.5
Saturday, Dec. 24 1:00 PM Cincinnati Bengals New England Patriots -3 +3 42.0
Saturday, Dec. 24 4:05 PM Washington Commanders San Francisco 49ers +6.5 -6.5 37.5
Saturday, Dec. 24 4:25 PM Philadelphia Eagles Dallas Cowboys +4.5 -4.5 47.0
Saturday, Dec. 24 8:15 PM Las Vegas Raiders Pittsburgh Steelers +2.5 -2.5 38.0
Saturday, Dec. 25 1:00 PM Green Bay Packers Miami Dolphins +3.5 -3.5 50.0
Saturday, Dec. 25 4:30 PM Denver Broncos Los Angeles Rams -3 +3 36.5
Saturday, Dec. 25 8:20 PM Tampa Bay Buccaneers Arizona Cardinals -7.5 +7.5 40.0
Monday, Dec. 26 8:15 PM Los Angeles Chargers Indianapolis Colts -4.5 +4.5 45.0

OFF = No odds currently listed.


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The 5 best bets for NFL Week 16

The smartest locks for Week 16 NFL betting action.

It’s beginning to look a lot like Christmas around the NFL (because the weather outside is frightful). This has led to some of the lowest Over/Under numbers in recent memory.

This week, we take three teams that need a win over inferior opponents to solidify their playoff stock and the Over in two games – one for two teams used to playing outside late in the season and the other with the highest O/U of the week.

Odds provided by Tipico Sportsbook

Betting the NFL Line: Week 16

Help pay for some of your holiday spending by making bank on these bets.

It’s been hard to avoid the discussion about a second massive weather system in two weeks that could impact a ton of games this week. As many as eight games could be played at or below freezing with wind and rain/snow potential for many of them.

As a result, nine of this Week’s 16 games have an Over/Under of 40 points or less. The oddsmakers are convinced we’re not going to see a lot of points and if wind is involved, they may well be right.

Odds provided by Tipico Sportsbook

NFL Betting Odds and Lines: Week 16

Jacksonville Jaguars (+105) at New York Jets (-125)

The Jets will have a big advantage in playing at home, but the Jaguars are on a roll after posting wins against the Baltimore Ravens, Tennessee Titans and Dallas Cowboys. This battle between the No. 1 and No. 2 picks of the 2021 draft should go to Trevor Lawrence. Take the Jaguars on the moneyline (+105).

Detroit Lions (-140) at Carolina Panthers (+120)

The Lions are steamrolling having won six of their last seven games. The Panthers have inconsistent, which helps explain why the Lions are small road favorites (2.5 points at -118 Lions, -102 Panthers). Dan Campbell has this team playing well and the Panthers offense can’t fully exploit Detroit’s defensive weaknesses. Take the Lions and lay 2.5 points (-118).

New York Giants (+170) at Minnesota Vikings (-200)

Minnesota is 11-3 but has had a horseshoe in its pocket that covers the Vikings’ mistakes. The only thing consistent about this team is it scores a lot of points and give up a lot as well. The Over/Under is high (48 points at -113 Over, 107 Under), but I’m willing to take my chances based on past performance that no lead is safe for either team. Take the Over (-113).

Buffalo Bills (-400) at Chicago Bears (+325)

The Bears kept things close with the Eagles last week, but their defense isn’t up for the challenge coming from Buffalo. The Over/Under on this game is low (40 points at -112 Over, -108 Under), but neither team is intimidated or limited by inclement weather, and the Bills should be able to take care of 30 of these points by themselves. Take the Over (-112).

Seattle Seahawks (+400) at Kansas City Chiefs (-500)

I’m leery of double-digit spreads, because I tend to take the team predicted to roll, but with this one I can’t help myself. The Chiefs are double-digit favorites (10 points at -111 Seahawks, -109 Chiefs). The No. 1 seed in the AFC is on the line, and nobody wants to get a scare like the Texans put in the Chiefs last week. They’ll be playing to knock out Seattle early. Take the Chiefs and lay 10 points (-109).

Atlanta Falcons (+280) at Baltimore Ravens (-340)

Lamar Jackson is not expected back, and the Ravens still have been established as a big favorite (7 points at -109 Falcons, -111 Ravens). I’m unconvinced the Falcons can generate enough offense to keep pace and, if they fall behind, a bad situation gets worse. Take the Ravens and lay 7 points (-111).

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New Orleans Saints (+130) at Cleveland Browns (-150)

This game a microscopic O/U (32.5 points), but dome teams heading into the kind of brutal weather anticipated for Cleveland on Saturday rarely succeed. The Browns are a modest favorite (3 points at -116 Saints, -104 Browns), and the number is begging people to bet on Cleveland’s running game and run defense. Count me in. Take the Browns and lay 3 points (-104).

Cincinnati Bengals (-170) at New England Patriots (+145)

The Bengals have won six straight and 10 of their last 12, and they’re up against a nondescript Patriots team that will struggle to control time of possession. The Pats are getting respect on the line as the Bengals are small road favorites (3 points at -118 Bengals, -102 Patriots). Cincinnati is capable of blowing out the Patriots. New England isn’t capable of doing the same. Take the Bengals and lay 3 points (-118).

Houston Texans (+140) at Tennessee Titans (-160)

The Titans are expected to be without Ryan Tannehill, so they are minimal favorites (3 points at -105 Texans, -115 Titans). Tennessee needs to win every game to assure they repeat as division champions, which means Derrick Henry will be saddled up and ridden as far as he can take them, which should be enough against Houston. Take the Titans and lay 3 points (-115).

Washington Commanders (+270) at San Francisco 49ers (-330)

Despite being on their third QB of the season, the 49ers have won seven straight games and are deservedly big favorites (7 points at -115 Commanders, -105 49ers). Washington has been a feel-good story this season, but the 49ers have a deep playoff run in front of them, and the Commanders won’t slow that down. Take the 49ers and lay 7 points (-105).

Philadelphia Eagles (+190) at Dallas Cowboys (-220)

With Jalen Hurts expected out, the line has jumped in favor of the Cowboys. The number I’m looking at the Over/Under (47 points at -112 Over, -108 Under). Gardner Minshew is among the better backup QBs in the league and shouldn’t prevent the Eagles from putting up points. Take the Over (-112).

Las Vegas Raiders (+120) at Pittsburgh Steelers (-140)

The Steelers are looking to prevent their first losing season under Mike Tomlin. They’re modest home favorites (2.5 points at -110 for both teams). The Pittsburgh fans are going to make life miserable, especially after the 50th anniversary honoring of Franco Harris takes place, and the Steelers will respond. Take the Steelers and lay 2.5 points (-110).

Green Bay Packers (+170) at Miami Dolphins (-200)

With all of the low Over/Under numbers this week, this is tied for the highest (49 points at -110 for both). It’s high for a reason. The Packers defense doesn’t have an answer for the explosive Dolphins receivers, and if you force Aaron Rodgers to pass 40 times, he will produce points. Take the Over (-110).

Denver Broncos (-135) at Los Angeles Rams (+115)

This is one of the lowest O/U numbers (36.5 points at -109 Over, -111 Under) of the week, but both defenses are stout and both offenses are not. When it number gets this low, it dares you to take the Over, but I’m not biting … or watching this train wreck. Take the Under (-111).

Tampa Bay Buccaneers (-350) at Arizona Cardinals (+280)

The Buccaneers have been a joke much of this season for the talent they have but are still massive road favorites (7.5 points at -110 for both teams). It looks like Arizona will down to its third quarterback (Trace McSorley). Seeing as their top two QBs struggled to put up points, it’s hard to imagine McSorley will be different. Take the Buccaneers and lay 7.5 points (-110).

Los Angeles Chargers (-210) at Indianapolis Colts (+180)

The Chargers are road favorites (4.5 points at -111 Chargers, -109 Colts). That isn’t enough. In their last two games, Indianapolis allowed Dallas to score 33 points in the fourth quarter and blew the biggest lead in NFL history against the Vikings. The Chargers are willing to pass every down, and the Colts are bad enough that it will succeed. Take the Chargers and lay 4.5 points (-111).


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NFL Picks: Office pool pick’em – Week 16

Use our staff’s weekly pick’em against the spread and straight up for the win.

The Huddle staff makes its weekly NFL game picks every Thursday.

NFL picks are provided for straight up (moneyline) and against the spread (ATS) NFL pick pools.

Each week’s spread picks are graded by the line as of when the person entered their picks. This will create situations in which a movement of the line can result in two participants having the correct pick but with different teams chosen during an individual game.

Odds provided by Tipico Sportsbook

NFL Week 16 picks: moneyline & against the spread


Season-to-date rankings: moneyline


Season-to-date rankings: ATS


NFL all-time picks leaderboard: moneyline

Straight Up DMD SG KP HS CC CJB HCG
2021 Record 167-104-1 159-112-1 179-92-1 176-95-1 175-96-1 176-95-1 174-97-1
2020 Record 161-94-1 161-94-1 165-90-1 164-91-1 174-81-1 166-89-1 172-83-1
2019 Record 162-93-1 156-99-1 161-94-1 161-94-1 164-91-1 157-98-1 163-92-1
2018 Record 167-87-2 158-96-2 179-75-2 153-101-2 165-89-2 157-97-2 n/a
2017 Record 168-88 161-95 171-85 165-91 180-76 160-96 n/a
2016 Record 157-97-2 149-105-2 156-98-2 152-102-2 156-98-2 139-115-2 n/a
2015 Record 154-102 137-119 156-100 155-101 165-91 n/a n/a
2014 Record 166-89-1 158-97-1 164-91-1 163-92-1 177-78-1 n/a n/a
2013 Record 163-92-1 160-95-1 170-85-1 153-102-1 n/a n/a n/a
Accuracy entering 2022 1,465-846-9
(63.1%)
1,399-912-9
(60.3%)
1,501-801-9
(64.7%)
1,442-869-9
(62.2%)
1,356-700-8
(65.7%)
955-590-7
(61.5%)
509-272-3
(64.9%)

NFL all-time picks leaderboard: ATS

ATS DMD SG KP HS CC CJB HCG
2021 Record 141-130-1 142-129-1 154-117-1 136-135-1 152-119-1 143-128-1 151-120-1
2020 Record 118-138 122-134 123-133 129-127 130-126 143-113 130-126
2019 Record 121-135 133-123 133-123 139-117 121-135 137-119 139-117
2018 Record 132-124 131-125 145-111 133-123 132-124 130-126 n/a
2017 Record 129-127 136-120 135-121 132-124 136-120 131-125 n/a
2016 Record 110-146 125-131 127-129 124-132 132-124 127-129 n/a
2015 Record 125-131 121-135 126-130 123-133 141-115 n/a n/a
2014 Record 122-134 124-132 143-113 132-124 123-133 n/a n/a
2013 Record 115-136-5 119-132-5 117-134-5 117-134-5 n/a n/a n/a
Accuracy entering 2022 1,113-1,201-6
(48.1%)
1,153-1,161-6
(50.7%)
1,203-1,111-6
(51.9%)
1,165-1,149-6
(50.2%)
1,067-996-1
(51.7%)
811-740-1
(52.3%)
420-363-1
(54.1%)

DMD – David Dorey, SG – Steve Gallo, KP – Ken Pomponio, HS – Harley Schultz, CC – Cletis Cutts, CJB – Cory Bonini, HCG – HC Green


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