5 Best NFL Predictions Against The Spread: Week 1

What 5 NFL games appear to be the best bets and the best picks against the spread going into Week 1 of the 2021 season? Here you go. Enjoy.

What 5 NFL games appear to be the best bets and the best picks against the spread going into Week 1 of the 2021 season? Here you go. Enjoy.


Week 1 NFL Predictions, Game Previews 
Week 1 NFL Predictions, Schedule, Times, Lines, Previews
CFN Fearless Predictions & Game Previews
CFN Expert Picks: NFL

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5. Chicago Bears at Los Angeles Rams

Line: Los Angeles -7.5
ATS Pick: Los Angeles

In Week 1, always like the underdogs by more than a touchdown – like Dallas on Thursday night against Tampa Bay – and always assume that the professional coaching staff on the big underdog side has something interesting ready to go to counteract what everyone knows is true.

In this case, just assume that Matt Nagy and the Bear coaches will find some way to overcome their abysmal offensive line to prevent Aaron Donald and company from jumping on Andy Dalton’s head all game long.

And about Dalton – he’s not going to be awful. It still won’t be enough.

The Bears will be okay, and the defense will have its moments, but Khalil Mack isn’t anywhere close to 100% – the line has to get to Matthew Stafford, or uh oh – and the Chicago offensive line really is going to be an issue.

LA won last year 24-10, and this time around it’s the opener in front of a whole lot of fans in the shiny stadium on Sunday night with the world watching.

Under pressure, Dalton throws a late pick that turns into Ram points to cover.

NEXT: Green Bay at New Orleans, Part 1

NFL Predictions, Schedule, Game Previews, Lines, TV: Week 1

NFL predictions, schedule, game previews, lines, and TV listings for Week 1 of the season.

NFL predictions, schedule, game previews, lines, and TV listings for Week 1 of the season.


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Click on each game for game preview & prediction

Results So Far
SU: 0-0, ATS: 0-0, Point Total: 0-0

Thursday, September 9

Dallas at Tampa Bay

8:20, NBC
Tampa Bay -7.5, o/u: 51

Sunday, September 12

Philadelphia at Atlanta

1:00, FOX
Line: Atlanta -3.5, o/u: 48

Pittsburgh at Buffalo

1:00, CBS
Line: Buffalo -6.5, o/u: 48.5

2021 Preseason NFL Predictions For Every Game

Minnesota at Cincinnati

1:00, FOX
Line: Minnesota -3, o/u: 48

San Francisco at Detroit

1:00, FOX
Line: San Francisco -7.5, o/u: 45.5

Arizona at Tennessee

1:00, CBS
Line: Tennessee -3, o/u: 52

Seattle at Indianapolis

1:00, FOX
Line: Seattle -2.5, o/u: 48.5

Los Angeles Chargers at Washington

1:00, CBS
Line: Los Angeles Chargers -1, o/u: 44.5

Week 1 NFL Expert Picks

New York Jets at Carolina

1:00, CBS
Line: Carolina -4.5, o/u: 44.5

Jacksonville at Houston

1:00, CBS
Line: Jacksonville -3, o/u: 45

Cleveland at Kansas City

4:25, CBS
Line: Kansas City -6, o/u: 53

Miami at New England

4:25, CBS
Line: New England -3, o/u: 43.5

2021 NFL Predictions For Every Game This Season

Green Bay at New Orleans

4:25, FOX
Line: Green Bay -3, o/u: 50

Denver at New York Giants

4:25, FOX
Line: Denver -2.5, o/u: 42

Chicago at Los Angeles Rams

8:20, NBC
Line: Los Angeles Rams -7.5, o/u: 44.5

Monday, September 13

Baltimore at Las Vegas

8:15, ESPN/ABC
Line: Baltimore -4.5, o/u: 51

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Week 1 NFL Expert Picks
2021 Preseason NFL Predictions For Every Game

NFL Expert Picks, Predictions, Lines: Week 1

NFL expert picks, predictions, lines for Week 1 highlighted by Dallas at Tampa Bay, Cleveland at Kansas City, and Green Bay at New Orleans

NFL expert picks, predictions, and lines for Week 1 highlighted by Dallas at Tampa Bay, Cleveland at Kansas City, and Green Bay at New Orleans.


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* next to the pick means the team will win, but not cover.
Click on each game for the game preview and CFN Prediction

CFN Fearless Predictions & Game Previews

Week 1 NFL Expert Picks
Dallas at TB | Phil at Atlanta
Pitt at Buff | Minn at Cincinnati
SF at Detroit | Arizona at Tenn
Seattle at Indy | Chargers at Wash

Jets at Carolina | Jax at Houston
Cleveland at KC | Miami at NE
GB at NO | Denver at Giants
Chicago at Rams | Balt at LV
The Experts and Picks So Far

Dallas at Tampa Bay

8:20, NBC
Line: Tampa Bay -7.5, o/u: 50.5

Gill Alexander, VSIN: Tampa Bay*
Jeff Feyerer, CFN: Tampa Bay
Pete Fiutak, CFN: Tampa Bay*
Phil Harrison, BuckeyesWire.com: Tampa Bay
Jeremy Mauss, , MWwire.com: Tampa Bay
Zac Neel, DucksWire.com: Tampa Bay*
Tyler Nettuno, GatorsWire.com: Tampa Bay
Big Game Ben Niewoehner, CFN Tampa Bay
Nick Shepkowski, @Shep670, FightingIrishWire.com: Tampa Bay*
John Williams, SoonersWire.com: Tampa Bay*
Clucko the Chicken, CFN: Dallas
CONSENSUS PICK: Tampa Bay*

NFL Predictions For Every Team

NEXT: Philadelphia at Atlanta Expert Picks, Predictions

NFL Predictions, Schedule, Game Previews, Lines, TV: Week 1

The Week 1 NFL predictions, TV schedules, fantasy players to watch, game previews and game times.

The Week 1 NFL predictions, TV schedules, game previews, fantasy players to watch, and game times.


All Listed Gametimes EST

Results So Far: SU 1-0, ATS 0-1, o/u: 0-0-1

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Click on each game for game preview & prediction

Thursday, September 10

Houston at Kansas City

CFN Houston at Kansas City Prediction, Preview
Line:
Kansas City -9.5, o/u: 54
Prediction: Kansas City 38, Houston 31
Final Score: Kansas City 34, Houston 20

Sunday, September 13

Seattle at Atlanta

CFN Seattle at Atlanta Prediction, Preview
1:00, FOX
Line: Seattle -1, o/u: 49
Bet on this at BetMGM

New York Jets at Buffalo

CFN New York Jets at Buffalo Prediction, Preview
1:00, CBS
Line: Buffalo -7, o/u: 40
Bet on this at BetMGM

Chicago at Detroit

CFN Chicago at Detroit Prediction, Preview
1:00, FOX
Line: Detroit -2.5, o/u: 42
Bet on this at BetMGM

Green Bay at Minnesota

CFN Green Bay at Minnesota Prediction, Preview
1:00, FOX
Line: Minnesota -2.5, o/u: 44.5
Bet on this at BetMGM

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Miami at New England

CFN Miami at New England Prediction, Preview
1:00, CBS
New England -7, o/u: 41.5
Bet on this at BetMGM

Philadelphia at Washington

CFN Philadelphia at Washington Prediction, Preview
1:00, FOX
Line: Philadelphia -5.5, o/u: 42
Bet on this at BetMGM

Las Vegas at Carolina

CFN Las Vegas at Carolina Prediction, Preview
1:00, CBS
Line: Las Vegas -3, o/u: 48
Bet on this at BetMGM

Indianapolis at Jacksonville

CFN Indianapolis at Jacksonville Prediction, Preview
1:00, CBS
Line: Indianapolis -8, o/u: 46
Bet on this at BetMGM

Cleveland at Baltimore

CFN Cleveland at Baltimore Prediction, Preview
1:00, CBS
Line: Baltimore -7.5, o/u: 47.5
Bet on this at BetMGM

Los Angeles Chargers at Cincinnati

CFN LA Chargers at Cincinnati Prediction, Preview
4:05, CBS
Line: Los Angeles -3, o/u: 41.5
Bet on this at BetMGM

Tampa Bay at New Orleans

4:25, FOX
Line: New Orleans -4, o/u: 47.5
CFN Tampa Bay at New Orleans Prediction, Preview
Bet on this at BetMGM

Arizona at San Francisco

CFN Arizona at San Francisco Prediction, Preview
4:25, FOX
Line: San Francisco -7, o/u: 48
Bet on this at BetMGM

Dallas at Los Angeles Rams

CFN Dallas at LA Rams Prediction, Preview
8:20, NBC
Line: Dallas -2, o/u: 51.5
Bet on this at BetMGM

Monday, September 14

Pittsburgh at New York Giants

CFN Pittsburgh at New York Giants Prediction, Preview
7:15, ESPN
Line: Pittsburgh -5.5, o/u: 46
Bet on this at BetMGM

Tennessee at Denver

CFN Tennessee at Denver Prediction, Preview
10:10, ESPN
Line: Tennessee -3, o/u: 41
Bet on this at BetMGM

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NFL Expert Picks, Predictions: Week 1

NFL expert picks, predictions for Week 1, highlighted by Tampa Bay vs New Orleans, Chicago vs Detroit, Houston at Kansas City

NFL expert picks, predictions for Week 1, highlighted by Tom Brady and Tampa Bay vs Drew Brees and New Orleans, Chicago vs Detroit, and Houston at Kansas City


Experts, Results So Far …

Gill Alexander: SU: 0-0, ATS: 0-0
@beatingthebook, VSIN
Jeff Feyerer: SU: 0-0, ATS: 0-0
@JeffFeyererFightingIrishWire.com
Pete Fiutak: SU: 0-0, ATS: 0-0
@PeteFiutakCFN 
Phil Harrison: SU: 0-0, ATS: 0-0
@PhilHarrisonBW, BuckeyesWire.com
Jeremy Mauss: SU: 0-0, ATS: 0-0
@MWCWire, MWwire.com
Scott Steehn: SU: 0-0, ATS: 0-0
@Steehnroller, WinnersandWhiners.com
Keith Stewart: SU: 0-0, ATS: 0-0
WinnersandWhiners.com
Brian Stultz: SU: 0-0, ATS: 0-0
Clucko The Chicken (a coin flip): SU: 0-0, ATS: 0-0
CONSENSUS PICK: SU: 0-0, ATS: 0-0

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Week 1 Expert Picks 
Cleveland at Baltimore | NY Jets at Buffalo
Las Vegas at Carolina | Seattle at Atlanta
Phil at Washington | Chicago at Detroit
Indy at Jacksonville | GB at Minnesota
LA Chargers at Cincinnati | Arizona at SF
Tampa Bay at New Orleans | Dallas at LA Rams
Pitt at NY Giants | Tennessee at Denver


If there’s an *next to the pick, that means the team will win, but not cover.

INSTRUCTIONS: Make your pick against the spread. For example …
– If you think Chicago will win -4 over Detroit: Chicago
– If you think Detroit will win outright: Detroit
– If you think Chicago will win, but NOT cover: Chicago*

Thursday, September 10

Houston at Kansas City

8:20, NBC
BetMGM Line: Kansas City -9.5, o/u: 54
Bet on this with BetMGM or for latest line 

Gill Alexander, VSIN: Kansas City*
Jeff Feyerer, Fighting Irish Wire: Kansas City*
Pete Fiutak, CFN: Kansas City*
Phil Harrison, Buckeyes Wire: Kansas City
Jeremy Mauss, MW Wire: Kansas City*
Scott Steehn, WinnersandWhiners: Kansas City
Keith Stewart, WinnersandWhiners: Kansas City
Clucko the Chicken, CFN: Houston
CONSENSUS PICK: Kansas City*

CFN College Football Week 1 Experts Picks

Sunday, September 13

Miami at New England

1:00, CBS
BetMGM Line: New England -6, o/u: 43
Bet on this with BetMGM or for latest line 

Gill Alexander, VSIN: Miami
Jeff Feyerer, Fighting Irish Wire: New England*
Pete Fiutak, CFN: New England
Phil Harrison, Buckeyes Wire: New England
Jeremy Mauss, MW Wire: New England*
Scott Steehn, WinnersandWhiners: New England*
Keith Stewart, WinnersandWhiners: New England*
Clucko the Chicken, CFN: Miami
CONSENSUS PICK: New England*

Week 1 Expert Picks 
Cleveland at Baltimore | NY Jets at Buffalo
Las Vegas at Carolina | Seattle at Atlanta
Phil at Washington | Chicago at Detroit
Indy at Jacksonville | GB at Minnesota
LA Chargers at Cincinnati | Arizona at SF
Tampa Bay at New Orleans | Dallas at LA Rams
Pitt at NY Giants | Tennessee at Denver

NEXT: Cleveland at Baltimore, NY Jets at Buffalo