The Pittsburgh Steelers and Buffalo Bills get their regular-season campaigns underway Sunday. Kickoff from Highmark Stadium in Buffalo, N.Y., is scheduled for 1 p.m. ET. Below, we look at the Steelers vs. Bills odds and lines; check back for our NFL picks and predictions.
Pittsburgh captured the AFC North title in 2020 before bowing out of the playoffs in the AFC Wild Card Round to the division rival Cleveland Browns. The AFC North is expected to be tightly contested again in 2021 and Pittsburgh will be looking for an improved run game.
The Steelers were the only team to average fewer than 90 rushing yards per game last year and selected RB Najee Harris in the first round of the NFL draft to rectify the situation. Pittsburgh finished the preseason 3-1 straight up, 2-2 against the spread and 3-1 against the Over/Under.
The Bills also captured a division title when they won the AFC East for the first time since 1995. Buffalo has seen consistent improvement from fourth-year signal-caller Josh Allen and is looking to build off last year’s AFC Championship Game appearance. The Bills concluded the preseason with a perfect 3-0 SU/ATS record and 1-2 O/U mark.
Steelers at Bills odds, spread and line
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 3:15 p.m. ET.
- Money line: Steelers +220 (bet $100 to win $220) | Bills -280 (bet $280 to win $100)
- Against the spread (ATS): Steelers +6.5, -110 (bet $110 to win $100) | Bills -6.5, -110 (bet $110 to win $100)
- Total (O/U): 47.5, Over -112 (bet $112 to win $100) | Under -108 (bet $1108 to win $100)
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2020 betting stats (regular season):
- ML: Steelers 12-4-0 | Bills 13-3-0
- ATS: Steelers 10-6-0 | Bills 11-5-0
- O/U: Steelers 7-7-2 | Bills 10-5-1
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Steelers at Bills head-to-head
The Steelers and Bills have met twice during the Josh Allen era. Buffalo picked up a decisive 26-15 victory at home in Week 14 last season and easily covering as a 2-point favorite while the game came in more than a touchdown below the projected total of 48.5 points.
The clubs last met in Pittsburgh in 2019 and the Bills emerged with a 17-10 victory while covering the spread as 1-point underdogs. The total sailed well Under the 37-point projected number that day too, although QB Ben Roethlisberger didn’t play.
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