Minnesota Vikings at San Francisco 49ers odds, picks and prediction

Analyzing Sunday’s Minnesota Vikings at San Francisco 49ers odds and lines, with expert NFL picks, predictions and best bets.

Two teams that looked dead in the water a couple of weeks ago – the Minnesota Vikings (5-5) and San Francisco 49ers (5-5) – meet up with a potential playoff spot at stake at 4:25 p.m. ET Sunday at Levi’s Stadium. Below, we look at the Vikings vs. 49ers odds and lines, and make our best NFL picks, predictions and bets.

The Vikings haven’t been above .500 all season, but coming off wins over the Chargers and Packers, Minnesota is playing some of its best ball of the season and, as things currently stand, are in possession of the second wild-card spot.

After dropping four straight in late September and October, the 49ers have won two straight in blowout fashion, including a 31-10 upset over the Rams and a 30-10 beatdown of the Jaguars.

The 49ers are the only NFC team other than Minnesota with a record of 5-5, which places San Francisco as the third wild card team.

Also see: All Week 12 odds and lines

Vikings at 49ers odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Saturday at 2:15 p.m. ET.

  • Money line: Vikings +140 (bet $100 to win $140) | 49ers -175 (bet $175 to win $100)
  • Against the spread (ATS): Vikings +3.5 (-120) | 49er -3.5 (+100)
  • Over/Under (O/U): 49.5 (O: -110 | U: -110)

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Vikings at 49ers key injuries

Vikings

  • DE Everson Griffen (personal) out
  • DT Dalvin Tomlinson (COVID-list) out
  • S Camryn Bynum (ankle) questionable

49ers

  • DT Maurice Hurst (calf) doubtful
  • RB Elijah Mitchell (finger) questionable

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Vikings at 49ers odds, lines, predictions and picks

Prediction

49ers 27, Vikings 24

Money line

The Vikings are really good at keeping games close. Eight of their nine games (including all five of their losses) have come by seven points or less. The 49ers have overcome numerous injuries to win three of their last four by 11, 21 and 20 points.

Like so many Minnesota games, this could come down to the last possession to determine a winner and, while either team could just as easily win, I’m leaning toward a late score that wins it for the 49ERS (-175)

Against the spread

There hasn’t been a blowout loss against the Vikings all season because they’re the only team in the NFL that has had a lead of seven points or more in every game this season. If they can make it 10 in a row, it could set the tone for the game because the 49ers aren’t a team built to erase a big deficit.

That’s why this one should stay close. There are plenty who will take the Vikings straight up. I’m much more comfortable hedging my bet and taking the VIKINGS +3.5 (-120)

Over/Under

The Vikings have scored 27 or more points in their last three games and four of their last five. The 49ers have scored 30 or more in each of their last three wins.

That helps explain why the Over/Under is so high (49.5 points). It’s there for a reason because that is the type of ball both teams are playing.

Take the OVER 49.5 (-110)

Also seeBet Slippin’ Podcast: NFL Week 12 picks and predictions

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First look: Minnesota Vikings at San Francisco 49ers odds and lines

Looking at Sunday’s Minnesota Vikings at San Francisco 49ers Week 12 NFL odds, lines and trends. Here’s what you need to know.

The Minnesota Vikings (5-5) and San Francisco 49ers (5-5) meet Sunday in Week 12 for a 4:25 p.m. ET kickoff at Levi’s Stadium. Below, we look at the Vikings vs. 49ers odds and lines; check back for our NFL picks and predictions.

The Vikings beat the visiting Green Bay Packers 34-31 in Week 11. PK Greg Joseph kicked a 29-yard field goal as time expired for Minnesota, which covered the spread as a 1-point underdog.

QB Kirk Cousins finished with 341 passing yards and 3 touchdowns as the Vikings claimed a second consecutive win and a third cover in a row.

The 49ers scored on their first five possessions in a 30-10 rout at the Jacksonville Jaguars Sunday.

QB Jimmy Garoppolo (176 passing yards) threw 2 touchdowns, RB Deebo Samuel (79 rushing yards) had a 25-yard TD run and PK Robbie Gould kicked 3 field goals as the 49ers won and covered a second game in a row.

Vikings at 49ers odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 12:03 a.m. ET.

  • Money line: Vikings +120 (bet $100 to win $120) | 49ers -145 (bet $145 to win $100)
  • Against the spread (ATS): Vikings +2.5, +100 (bet $100 to win $100) | 49ers -2.5, -120 (bet $120 to win $100)
  • Over/Under (O/U): 48.5, O: -110 (bet $110 to win $100) | U: -110 (bet $110 to win $100)

PLAY: Try our new, free daily Pick’em Challenge and win. Play now!

2021 betting stats:

  • ML: Vikings 5-5 | 49ers 5-5
  • ATS: Vikings 6-4 | 49ers 4-6
  • O/U: Vikings 5-5 | 49ers 5-5

WIN YOUR FANTASY FOOTBALL LEAGUE!

For 25 years, TheHuddle.com has been helping fantasy players just like you win. This year, it’s your turn! Custom player rankings, tools and more to give you the edge over your competition.

Use code SBW21 to take 20% OFF a new subscription. Join now!

Vikings at 49ers head-to-head

Minnesota leads 22-19-1 in regular-season meetings, but San Francisco holds a 5-1 edge in postseason matchups.

They last met in the 2019-20 postseason with the 49ers claiming a 27-10 NFC Divisional Round victory as 7-point home favorites.

They split their four games since 2010 with the home team going 4-0 SU and 4-0 ATS. The Under cashed in each of the four meetings.

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

Follow @JohnnyParlay11 on Twitter. SportsbookWire on Twitter and like us on Facebook.

Access more NFL coverage:

TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | WashingtonFootballWire | DraftWire | TouchdownWire | TheListWire

Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. See Tipico.com for Terms and Conditions. 21+ only. Gambling problem? Call 1-800-GAMBLER (NJ), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA).

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