Minnesota Twins at Cleveland Guardians odds, picks and predictions

Analyzing Thursday’s Minnesota Twins at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Minnesota Twins (80-72) and Cleveland Guardians (88-65) wrap up a 4-game series Thursday. First pitch from Progressive Field is set for 1:10 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s MLB odds around the Twins vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 9-3

The Twins took a 4-2 lead in the top of the 10th inning in Wednesday’s game, but the Guardians erupted for 3 runs in the bottom of the frame to escape with the 5-4 win as slight favorites (-128). OF Brayan Rocchio drove in the game-winning run.

It was a terrible way for Twins moneyline (ML) bettors to lose, but even worse for those betting the Under (7). It was 2-2 after 9 innings, but the teams combined for 5 runs in the 10th.

Minnesota is now just 5-10 across the past 15 games, while cashing the Over at a 6-1-1 pace in the previous 8 outings. The Twins are just 2-7 in the past 9 road contests, too.

Twins OF Trevor Larnach is nursing a hamstring injury, and he has been limited to DH duties in the past 6 games.

The Guardians have posted 4 wins in the past 5 outings. The miraculous Over result Wednesday was rare, as the Under was 13-1-2 in the previous 16 contests. Cleveland’s magic number now stands at 1.

Twins at Guardians projected starters

RHP Simeon Woods Richardson vs. LHP Joey Cantillo

Woods Richardson (5-5, 4.08 ERA) makes his 27th start. He has a 1.25 WHIP, 3.2 BB/9 and 7.7 K/9 in 128 IP.

  • Last start: Loss, 3 IP, 3 ER, 5 H, 3 BB, 3 K in 11-1 home setback vs. Cincinnati Reds Saturday
  • 2024 road splits: 4-3, 4.25 ERA, 65 2/3 IP, 31 ER, 8 HR, 1.36 WHIP, .263 opponents’ batting average (OBA), 22 BB, 49 K in 14 starts
  • Last 7 games: 2-3, 4.68 ERA, 32 2/3 IP, 17 ER, 15 BB, 25 K, 1.32 WHIP
  • Career vs. Guardians: 0-1, 2.19 ERA (12 1/3 IP, 3 ER), 2 HR, 0 BB, 9 K, 0.65 WHIP, 6.6 K/9 in 2 starts

Cantillo (2-3, 4.99 ERA) makes his 7th start and 8th career appearance. He has a 1.17 WHIP, 2.9 BB/9 and 9.1 K/9 in 30 2/3 IP.

  • Last start: Win, 5 IP, 0 ER, 3 H, 1 BB, 6 K in 6-1 home victory vs. Tampa Bay Rays Saturday
  • 2024 home splits: 1-1, 2.53 ERA, 10 2/3 IP, 3 ER, 0 HR, 0.94 WHIP, .225 OBA, 1 BB, 11 K in 2 starts (3 appearances)
  • Career vs. Twins: Loss, 5 2/3 IP, 3 ER, 5 H, 3 BB, 2 K in 1 start, a 4-2 road setback Aug. 9

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Twins at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated Wednesday at 11:53 p.m. ET.

  • Moneyline: Twins -105 (bet $105 to win $100) | Guardians -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): Twins -1.5 (+155) | Guardians +1.5 (-190)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

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Twins at Guardians picks and predictions

Prediction

Guardians 4, Twins 3

Moneyline

The GUARDIANS (-115) are the play, as they look to clinch a postseason spot Thursday afternoon.

It will be interesting to see how the Twins (-105) react to Wednesday’s gut-wrenching defeat. They’re likely not going to fare terribly well, as the Twins are just 21-22 this season against left-handed starting pitchers.

Run line/Against the spread

If you can’t trust Cleveland at home, backing Guardians +1.5 (-190) is just a little too expensive for insurance. Cleveland will cost you nearly 2 times your potential return.

If you were to toss the Guardians into a multi-leg parlay, it’s perfectly OK to include them, but playing Cleveland straight up on the run line is not recommended.

PASS.

Over/Under

UNDER 8.5 (-110) is a strong play in the series finale under the sun.

The winds will be blowing in from the left-center field power alley into the face of the batters at a 6-10 mph pace, picking up as the game goes along.

Despite the Over Wednesday, the Under is still 13-2-2 in the past 17 games for the Guardians, while going 4-2-2 in the past 8 in the series.

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Minnesota Twins at Cleveland Guardians odds, picks and predictions

Analyzing Wednesday’s Minnesota Twins at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Minnesota Twins (80-71) and Cleveland Guardians (87-65) meet for the 3rd game of a 4-game series Wednesday. First pitch from Progressive Field is set for 6:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Twins vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Cleveland leads 8-3

Minnesota beat Cleveland 4-1 Tuesday as a +121 road underdog. The Twins scored 3 unanswered runs after the 5th inning to break the 1-1 tie.

Guardians SP Gavin Williams allowed 2 earned runs on 5 hits and 2 walks with 7 K’s in 5 innings and recorded the loss. The setback ended a 3-game win streak for the Guardians, who are battling for the division title with Minnesota and the Kansas City Royals.

Twins at Guardians projected starters

RHP Bailey Ober vs. RHP Tanner Bibee

Ober (12-7, 3.90 ERA) makes his 29th start. He has a 0.99 WHIP, 2.3 BB/9 and 9.4 K/9 through 161 2/3 innings.

  • Last start: Loss, 6 2/3 IP, 5 ER, 6 H, 2 BB, 6 K in 8-4 home defeat vs. Cincinnati Reds Friday
  • Career vs. Cleveland: 2-2, 2.13 ERA (38 IP, 9 ER), 0.90 WHIP, 8.1 K/9 in 7 starts

Bibee (11-8, 3.60 ERA) makes his 30th start. He has a 1.14 WHIP, 2.3 BB/9 and 9.8 K/9 through 160 innings.

  • Last start: Loss, 6 IP, 3 ER, 8 H, 0 BB, 9 K in 3-1 home setback vs. Tampa Bay Rays Friday
  • Career vs. Minnesota: 2-0, 2.73 ERA (33 IP, 10 ER), 1.18 WHIP, 10.9 K/9 in 6 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Twins at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated Tuesday at 12:05 a.m. ET.

  • Moneyline (ML): Twins +100 (bet $100 to win $100) | Guardians -120 (bet $120 to win $100)
  • Run line (RL)/Against the spread (ATS): Twins -1.5 (+170) | Guardians +1.5 (-210)
  • Over/Under (O/U): 7.5 (O: -105 | U: -115)

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Twins at Guardians picks and predictions

Prediction

Guardians 4, Twins 2

Moneyline

BET GUARDIANS (-120).

Cleveland is 3-1 in its last 4 home games and 6-3 in its last 9 overall, while the Twins are 1-3 in their last 4 on the road and 4-6 in their last 10 overall.

The Guardians are also 4-1 in the last 5 meetings between these teams in Cleveland and 7-3 in the last 10 overall.

Run line/Against the spread

PASS.

I expect the Guardians to cover here as +1.5 (-210) underdogs, but their odds are better on the ML and this line is not worth the risk. Bet the ML and/or total instead.

Over/Under

BET UNDER 7.5 (-115).

The Under has hit in 5 of Cleveland’s last 6 home games and is 8-1-1 in its last 10 overall. For Minnesota, the Under is 3-0-1 in its last 4 road games. The Under is also 3-1-1 in the last 5 meetings in Cleveland and 6-2-2 in the last 10 overall.

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Minnesota Twins at Cleveland Guardians odds, picks and predictions

Analyzing Tuesday’s Minnesota Twins at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Minnesota Twins (79-71) and the Cleveland Guardians (87-64) play the 2nd contest of a 4-game series on Tuesday. First pitch from Progressive Field is set for 6:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Twins vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 8-2

The Twins fired out to a 3-0 lead in the top of the 3rd inning Monday, but Cleveland outscored Minnesota 4-0 in the final 5 innings, including a go-ahead 2-run HR by rookie Kyle Manzardo in the bottom of the 8th inning.

Cleveland has managed 40 come-from-behind victories this season, and the magic number for the Guardians to clinch a playoff spot is now just 2. Closer Emmanuel Clase was able to nail down his 46th save, as Cleveland improved to 46-27 at home, best mark in the AL.

The Under (7.5) hung on in the series opener, halting a 5-game Over streak for the Twins.

For the Guardians, the Under is now 13-1-2 across the previous 16 outings. Cleveland has posted 6 wins in the past 8 games, while going 6-3 in the previous 9 outings at Progressive Field.

Twins at Guardians projected starters

RHP Zebby Matthews vs. RHP Gavin Williams

Matthews (1-3, 7.11 ERA) makes his 7th career start. He has a 1.66 WHIP, 1.8 BB/9 and 9.6 K/9 in 25 1/3 IP.

  • Last start: No-decision, 3 1/3 IP, 2 ER, 5 H (2 solo HR), 2 BB, 5 K in 6-4 home victory vs. Los Angeles Angels last Wednesday
  • 2024 road splits: 0-2, 5.40 ERA, 10 IP, 6 ER, 1 HR, 1.60 WHIP, .295 opponents’ batting average (OBA), 3 BB, 5 K in 2 starts
  • 2024 splits vs. Central Division: 1-1, 5.40 ERA, 10 IP, 6 ER, 2 HR, .318 OBA, 1 BB, 9 K in 2 starts
  • Has never faced Guardians

Williams (3-9, 5.23 ERA) makes his 15th start. He has a 1.39 WHIP, 3.9 BB/9 and 9.5 K/9 in 65 1/3 IP.

  • Last start: Loss, 5 1/3 IP, 3 ER, 7 H (1 HR), 2 BB, 5 K in 5-2 setback vs. Tampa Bay Rays Thursday
  • 2024 home splits: 0-6, 7.07 ERA, 28 IP, 22 ER, 5 HR, 1.75 WHIP, .319 OBA, 12 BB, 35 K in 6 starts
  • Career vs. Twins: 2-0, 1.50 ERA, 12 IP, 2 ER, 5 BB, 7 K, 0.83 WHIP in 3 starts

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Twins at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 12:27 a.m. ET.

  • Moneyline (ML): Twins +105 (bet $100 to win $105) | Guardians -125 (bet $125 to win $100)
  • Run line (RL)/Against the spread (ATS): Twins +1.5 (-225) | Guardians -1.5 (+165)
  • Over/Under (O/U): 8 (O: -125 | U: -105)

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Twins at Guardians picks and predictions

Prediction

Twins 4, Guardians 3

Moneyline

Look for the TWINS (+105) to return the favor in Game 2 of this series after a heartbreaking loss in Monday’s opener.

Minnesota got off to a tremendous start, but it was unable to hang onto the lead, as Josh Naylor and Manzardo provided the late-game heroics to get the game to Clase to close it out.

While Matthews isn’t a rock-solid option as a starter for the Twins, Williams has been a disaster at Progressive Field, going 0-6 with a 7.07 ERA in 28 IP across 6 starts in front of the home fans.

Run line/Against the spread

If you need a little insurance, Twins +1.5 (-225) will set you back more than 2 times your potential return. That’s just too much risk for not nearly enough reward.

If you like Minnesota, just pick it straight up.

AVOID.

Over/Under

UNDER 8 (-105) is the play in all Guardians games until further notice.

The Under held on in Monday’s game, and it is now 13-1-2 in the past 16 contests for Cleveland. The Under is also 4-1-1 in the past 6 meetings in this series, too.

In addition, the Over-Under is 1-1 in 2 road starts for Matthews, so not much to glean there. The total has gone low at a 4-0-1 clip in the past 5 starts for Williams.

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Minnesota Twins at Cleveland Guardians odds, picks and predictions

Analyzing Monday’s Minnesota Twins at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Minnesota Twins (79-70) and the Cleveland Guardians (86-64) open a 4-game series on Monday (ESPN+). First pitch from Progressive Field is set for 6:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s MLB odds around the Twins vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 7-2

The Twins salvaged the series final against the Cincinnati Reds on Sunday, winning 9-2 as a moderate (-166) favorite as the Over (9) cashed. Minnesota has won 3 of the past 5 games, while cashing the Over in all 5 outings.

The Guardians earned the split of the 4-game series against the Tampa Bay Rays on Sunday, winning 2-0 behind RHP Ben Lively. The Under cashed in all 4 games of the series at home, with Cleveland averaging 2.8 runs per game (RPG) on offense, while allowing just 2.3 RPG.

Cleveland has won 5 of the past 7 games, while going 5-3 in the previous 8 contests at Progressive Field. The Under is 12-1-2 in the previous 15 games, too.

These teams met in Cleveland May 17-19, with the Guardians earned the 3-game sweep while outscoring the Twins 19-8, as the Under cashed in 2 of the 3 outings.

Twins at Guardians projected starters

RHP Pablo Lopez vs. LHP Matthew Boyd

Lopez (15-8, 3.88 ERA) makes his 30th start. He has a 1.13 WHIP, 1.9 BB/9 and 9.7 K/9 in 169 1/3 IP.

  • Last start: Win, 7 IP, 4 R (0 ER), 8 H (1 HR), 1 BB, 10 K in 10-5 home victory vs. Los Angeles Angels last Tuesday
  • 2024 road splits: 8-4, 4.11 ERA, 87 2/3 IP, 40 ER, 14 HR, 1.11 WHIP, .222 opponents’ batting average (OBA), 24 BB, 100 K in 15 starts
  • Last 7 games: 5-1, 1.79 ERA, 45 1/3 IP, 9 ER, 7 BB, 41 K, 1.13 WHIP
  • Career vs. Guardians: 2-2, 3.64 ERA, 29 2/3 IP, 12 ER, 32 H, 10 BB, 21 K in 5 starts

Boyd (2-1, 2.18 ERA) makes his 7th start. He has a 0.91 WHIP, 1.9 BB/9 and 9.6 K/9 in 33 IP.

  • Last start: No-decision, 4 1/3 IP, 4 R (1 ER), 6 H, 2 BB, 9 K in 6-4 road win vs. Chicago White Sox Wednesday
  • 2024 home splits: 1-1, 1.56 ERA, 17 1/3 IP, 3 ER, 0 HR, 0.63 WHIP, .167 OBA, 1 BB, 18 K in 3 starts
  • Career vs. Twins: 9-8, 4.62 ERA, 132 1/3 IP, 68 ER, 40 BB, 134 K, 1.10 WHIP in 23 starts (1 CG)

Who’s going yard? Here’s a breakdown of today’s best home run props with our top picks. Include the BetMGM bonus code SBWIRE to score a $1,500 first-bet offer.

Twins at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list of MLB odds. Lines last updated at 6:33 a.m. ET.

  • Moneyline (ML): Twins -115 (bet $115 to win $100) | Guardians -105 (bet $105 to win $100)
  • Run line (RL)/Against the spread (ATS): Twins -1.5 (+150) | Guardians +1.5 (-185)
  • Over/Under (O/U): 7.5 (O: -125 | U: -105)

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Twins at Guardians picks and predictions

Prediction

Twins 4, Guardians 2

Moneyline

The TWINS (-115) are a solid play as a slight road favorite in this series opener.

Lopez has been on fire lately, going 5-1 with a 1.79 ERA across his past 7 starts. It won’t be easy, as the left-hander Boyd has also pitched well since making his team debut. It will be tough, but Minnesota is a strong option to get off on the right foot.

Run line/Against the spread

If you’re a little more on the adventurous side, play the TWINS -1.5 (+150) on the run line rather than the moneyline.

Minnesota has just 3 wins in the past 9 games, but it has won by 2 or more runs in each of those victories. So, if you like the Twins to win, you should like them to get the job done on the run line, too.

Over/Under

UNDER 7.5 (-105) is a great play in this AL Central Division showdown.

The Under is 3-1-1 in the past 5 meetings. While the Over has connected at a 5-0 pace for the Twins, the total has gone low at a crazy 12-1-2 pace across the previous 15 outings for the Guardians.

The Under is 3-1 in Boyd’s past 4 starting assignments, too, while the total has gone low at a 2-1-1 clip in Lopez’s past 4 outings.

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Minnesota Twins at Cleveland Guardians odds, picks and predictions

Analyzing Saturday’s Minnesota Twins at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Cleveland Guardians (28-17) welcome the Minnesota Twins (24-20) to Progressive Field Saturday. First pitch in the 2nd game of the 3-game series is set for 6:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Twins vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 1-0

The Guardians won the first game of the series 3-2, closing as -125 favorites. They failed to cover as run-line favorites, but they are still 3-2 against the spread (ATS) over their last 5 games. Cleveland is the 3rd-best team in MLB at home with a 13-6 record.

The Twins have struggled as of late, losing 4 straight games and going 1-3 ATS in that stretch. They were swept by the New York Yankees in their last series but were 5-2 over the 2 series prior. Minnesota is 13-9 on the road.

Twins at Guardians projected starters

RHP Bailey Ober vs. LHP Logan Allen

Ober (4-1, 3.77 ERA) makes his 9th start. He has a 0.88 WHIP, 1.7 BB/9 and 9.4 K/9 in 43 innings.

  • Last start: Win, 6 1/3 IP, 0 ER, 1 H, 0 BB, 10 K in 5-1 road win over Toronto Blue Jays May 11
  • 2024 road splits: 3-1, 4.67 ERA (27 IP, 14 ER), 22 H, 4 HR, 4 BB, 25 K in 5 starts
  • Career vs. Guardians: 1-1, 1.29 ERA (28 IP, 4 ER), 0.75 WHIP, 6.8 K/9 in 5 starts

Allen (4-2, 5.56 ERA) makes his 10th start. He has a 1.50 WHIP, 3.0 BB/9 and 7.1 K/9 in 45 1/3 innings.

  • Last start: Win, 6 IP, 0 ER, 6 H, 1 BB, 3 K in 7-0 road win over Chicago White Sox Sunday
  • 2024 home splits: 1-0, 9.87 ERA (17 1/3 IP, 19 ER), 25 H, 6 HR, 8 BB, 14 K in 4 starts
  • Career vs. Twins: 1-0, 3.09 ERA (11 /23 IP, 4 ER), 1.54 WHIP, 5.4 K/9 in 2 starts

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Twins at Guardians odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:05 a.m. ET.

  • Moneyline (ML): Twins -118 (bet $118 to win $100) | Guardians +100 (bet $100 to win $100)
  • Run line (RL)/Against the spread: Twins -1.5 (+146) | Guardians +1.5 (-178)
  • Over/Under (O/U): 7.5 (O: +102 | U: -124)

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Twins at Guardians picks and predictions

Prediction

Twins 4, Guardians 3

Moneyline

BET TWINS (-118).

The Twins have been a strong side with Ober on the mound, and the opposite can be said of Allen. In Allen’s last 3 starts, the Guardians have given up 19 runs and gone 1-2. Ober has allowed 2 or fewer ER in 6 of his last 7 starts.

Minnesota is 17-10 straight up as a favorite and did have a 12-game win streak earlier in the season. With a strong starting option on the mound and success as a favorite, back TWINS (-118).

Run line/Against the spread

PASS.

There’s just no value on the run line here. The Twins are too risky as favorites, while the Guardians are far too expensive as run-line underdogs.

Over/Under

LEAN UNDER 7.5 (-124).

The Twins have gone Under in 5 straight games and struggled immensely on offense, scoring 2 or fewer in 4 straight. Allen’s recent issues could aid Minnesota, but it still hasn’t batted well as of late.

The Guardians have gone Under in 5 of their last 6 games. They are 4-8 O/U in their last 12 games. Given those recent trends, bet UNDER 7.5 (-124).

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Minnesota Twins at Cleveland Guardians odds, picks and predictions

Analyzing Friday’s Minnesota Twins vs. Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Minnesota Twins (24-19) and Cleveland Guardians (27-17) open a 3-game series at Progressive Field on Friday. First pitch is scheduled for 7:10 p.m. ET (Apple TV+). Let’s analyze FanDuel Sportsbook’s lines around the Twins vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 2-0

The Twins were blanked in the final 2 outings in a 3-game sweep against the New York Yankees at Target Field. And in the first game, Minnesota lost 5-1 on Tuesday night. The Under has cashed in 4 straight games, although the total has gone high in 5 of the past 6 outings against AL Central teams.

The Guardians were blanked 4-0 against the Texas Rangers Wednesday in the series finale, but Cleveland won the 1st 2 games by a combined score of 14-4, with a shutout in Monday’s game. In fact, Cleveland has allowed 4 or fewer runs in 5 consecutive games. The Under is 4-1 in the past 5 contests for the Guardians.

Twins at Guardians projected starters

RHP Simeon Woods Richardson vs. RHP Triston McKenzie

Woods Richardson (1-0, 3.24 ERA) makes his 6th start. He has a 1.24 WHIP, 2.2 BB/9 and 8.3 K/9 in 25 IP.

  • Last start: No-decision, 4 1/3 IP, 5 ER, 8 H (2 HR), 1 BB, 2 K in 10-8 road loss vs. Toronto Blue Jays last Saturday
  • 2024 vs. AL Central: (1-0, 2.45 ERA), 14 2/3 IP, 5 R (4 ER), 16 H, 4 BB, 13 K in 3 starts

McKenzie (2-3, 3.54 ERA) makes his 9th start. He has a 1.38 WHIP, 5.3 BB/9 and 7.8 K/9 in 40 2/3 innings.

  • Last start: Loss, 6 2/3 IP, 2 R (1 ER), 4 H, 3 BB, 5 K in 3-1 road loss vs. Chicago White Sox May 11
  • 2024 home splits: (2-1, 3.42 ERA), 23 2/3 IP, 10 R (9 ER), 19 H, 18 BB, 22 K in 5 starts

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Twins at Guardians odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 7:01 a.m. ET.

  • Moneyline (ML): Twins +100 (bet $100 to win $100) | Guardians -118 (bet $118 to win $100)
  • Run line (RL)/Against the spread (ATS): Twins -1.5 (+158) | Guardians +1.5 (-192)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Twins at Guardians picks and predictions

Prediction

Guardians 4, Twins 3

Moneyline

The GUARDIANS (-118) are worth playing in the series opener Friday at Progressive Field.

Cleveland has won 3 of the past 4 games, including a pair of shutouts. The Guardians topped the Twins (+100) in a pair of home games April 4-6.

Run line/Against the spread

The Guardians +1.5 (-192) are too expensive to play on the run line, so PASS, if you normally like a little insurance.

On the flip side, the Twins -1.5 (+158) also cannot be trusted. Remember, this is a Minnesota team which lost 3 in a row against the Yankees earlier this week, accounting for just a single run in 3 outings.

Over/Under

UNDER 8 (-115) is the play in this AL Central Division battle between 2 rivals.

The Under has cashed in 4 of the past 5 games for Cleveland, and the winning team has ended up shutting out the opposition 3 times during the span.

For the Twins, the total has gone low in 4 straight games. But be careful, as the Over cashed May 11, the last time out for Woods Richardson in a loss to the Blue Jays.

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Minnesota Twins at Cleveland Guardians odds, picks and predictions

Analyzing Wednesday’s Minnesota Twins at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Minnesota Twins (73-66) and Cleveland Guardians (66-73) meet Wednesday for the finale of their 13-game season series. First pitch from Progressive Field is set for 1:10 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Twins vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 6-6

Minnesota won 8-3 as a -110 road favorite to take a 2-0 series lead Tuesday. Minnesota trailed 3-2 heading into the 6th, but scored 6 runs in the 6th and 8th innings to win the game.

The Twins have won back-to-back games and are 6-4 in their last 10 overall. Minnesota is 33-37 on the road. Cleveland is 35-36 at home and has lost 3-straight. The Guardians are 5-5 in their last 10.

Twins at Guardians projected starters

RHP Joe Ryan vs. RHP Gavin Williams

Ryan (10-8, 4.20 ERA) makes his 25th start. He has a 1.12 WHIP, 1.8 BB/9 and 10.9 K/9 in 137 innings.

  • Last outing: Win, 6 IP, 1 ER, 3 H, 0 BB, 7 K in a 5-1 road win Friday vs. the Texas Rangers
  • Career vs. Cleveland: 3-2, 1.83 ERA (44 1/3 IP, 9 ER), 28 H, 0.74 WHIP, 6.9 K/9 in 7 starts

Williams (1-5, 3.46 ERA) makes his 14th start. The rookie has a 1.28 WHIP, 3.4 BB/9 and 9.4 K/9 in 65 innings.

  • Last outing: No-decision, 1 IP, 0 ER, 0 H, 1 BB, 0 K in a 4-2 road loss Aug. 29 vs. Minnesota Twins
  • Career vs. Minnesota: 1 IP, 0 ER, 0 H, 1 BB, 0 K in 1 start

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Twins at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:03 a.m. ET.

  • Moneyline (ML): Twins -135 (bet $135 to win $100) | Guardians +110 (bet $100 to win $110)
  • Run line (RL)/Against the spread (ATS): Twins -1.5 (+125) | Guardians +1.5 (-150)
  • Over/Under (O/U): 8.5 (O: -115 | U: -105)

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Twins at Guardians picks and predictions

Prediction

Twins 6, Guardians 5

Moneyline

LEAN TWINS (-135).

These teams have been very evenly matched as a 6-6 season series attests, but the Twins do have a slight edge with the Guardians starting a rookie and this likely being a bullpen game for Cleveland. Neither pitcher is hot, but Ryan is the better SP here.

Run line/Against the spread

BET GUARDIANS +1.5 (-155).

I believe the Twins will win as they carry all the momentum, but the Guardians’ home crowd should give them some life and propel them to keep the game close. Of course, it’s understandable if you do not want to pay the juice here.

Over/Under

LEAN OVER 8.5 (-115).

The Over has hit in the 1st 2 games of the series. The Over is also 4-0 in Minnesota’s last 4 games overall and 6-4 in Cleveland’s last 10. The Over is 3-1-1 in Ryan’s last 5 starts, but it’s a lean because the Under is 3-0 in Ryan’s last 3 starts vs. Cleveland.

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Minnesota Twins at Cleveland Guardians odds, picks and predictions

Analyzing Tuesday’s Minnesota Twins at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Minnesota Twins (72-66) and the Cleveland Guardians (66-72) play the middle contest of a 3-game series Tuesday at Progressive Field. First pitch is scheduled for 6:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Twins vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 6-5

The Twins entered Monday’s series opener having won just 4 of the first 10 meetings against the Guardians this season, but Minnesota did plenty of work on Labor Day. The Twins belted out a 20-6 victory, with 6 different players smacking homers.

Twins rookie 3B Royce Lewis socked his 3rd grand slam and 5th home run in an 8-game span. That feat puts him in an exclusive 2-player club with Lou Gehrig, who also accomplished it in 1931.

The Guardians scratched out 3 of their 6 runs in the bottom of the 9th inning when the game was already well in hand for the Twins. Cleveland is averaging a respectable 5.1 runs per game (RPG) across the past 10 outings, well above the season average of 4.1 RPG.

Twins at Guardians projected starters

RHP Sonny Gray vs. RHP Tanner Bibee

Gray (7-6, 2.92 ERA) makes his 28th start. He has a 1.17 WHIP, 2.9 BB/9 and 8.9 K/9 in 157 innings.

  • Last start: No-decision, 7 IP, 0 ER, 3 H, 1 BB and 5 K in 5-2 home loss vs. Guardians Wednesday
  • 2023 road splits: 3-3, 3.07 ERA (73 1/3 IP, 25 ER), 3 HR, .225 opponent batting average (OBA) in 13 starts
  • 2023 vs. Cleveland: 0-1, 2.89 ERA (18 2/3 IP, 6 ER), 1 HR, 13 K and .239 OBA in 3 starts

Bibee (10-3, 3.03 ERA) makes his 23rd start. He has a 1.21 WHIP, 2.9 BB/9 and 9.0 K/9 in 124 2/3 innings.

  • Last start: No-decision, 5 IP, 2 ER, 4 H, 3 BB, 8 K in 5-2 road win vs. Twins Wednesday
  • 2023 home splits: 5-2, 2.02 ERA (58 IP, 13 ER), 2 HR, .194 OBA in 10 starts
  • 2023 vs. Minnesota: 0-0, 4.50 ERA (10 IP, 5 ER), 1 HR, 14 K and .256 OBA in 2 starts

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Twins at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 5:21 a.m. ET.

  • Moneyline (ML): Twins -115 (bet $115 to win $100) | Guardians -105 (bet $105 to win $100)
  • Run line (RL)/Against the spread (ATS): Twins -1.5 (+150) | Guardians +1.5 (-185)
  • Over/Under (O/U): 8 (O: -105 | U: -115)

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Twins at Guardians picks and predictions

Prediction

Twins 3, Guardians 2

Moneyline

The TWINS (-115) broke out the hitting shoes Monday, leaving the yard frequently like it was batting practice. Minnesota should have less success against the rookie Bibee, who has been a revelation for Tito Francona in Cleveland. The right-hander will keep the Guardians in it, but the hot-hitting Twins will still get it done eventually.

Run line/Against the spread

The Guardians +1.5 (-185) will cost you nearly 2 times your potential return if you like them to keep it within a single run. While it’s likely Cleveland keeps this one close in a pitcher’s duel, it’s just too much risk and not enough reward.

PASS.

Over/Under

UNDER 8 (-115) is the lean, as Gray has tremendous splits on the road, and Bibee has done most of his very good work at home.

While it’s risky business going low on the total after Minnesota registered 20 runs on Monday, it’s the way to go. Despite the Over on Monday, the Under is still 5-2 in the past 7 meetings between these AL Central rivals.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Minnesota Twins at Cleveland Guardians odds, picks and predictions

Analyzing Monday’s Minnesota Twins at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Minnesota Twins (71-66) and the Cleveland Guardians (66-71) open a 3-game series Monday at Progressive Field. First pitch is scheduled for 4:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Twins vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 6-4

The Twins fell 6-5 in the series finale of a 3-game set at the Texas Rangers Sunday, failing to complete the 3-game sweep. The Over cashed in the final 2 games of the Texas series and has hit at an 8-3-1 clip in the past 12 contests overall for Minnesota.

The Guardians took 2 of 3 games from the Twins last week in Minneapolis as they continue to hang around in the AL Central. Cleveland is 5 games back of the first-place Twins with 25 regular-season games remaining.

Cleveland added veteran RHP Lucas Giolito from the Los Angeles Angels last week on waivers, and he makes his team debut.

Twins at Guardians projected starters

RHP Pablo Lopez vs. RHP Lucas Giolito

Lopez (9-7, 3.72 ERA) makes his 28th start. He has a 1.16 WHIP, 2.4 BB/9 and 10.7 K/9 in 164 2/3 innings.

  • Last start: Loss, 6 IP, 3 ER, 8 H, 3 BB and 5 K in 4-2 home loss vs. Guardians Tuesday
  • 2023 road splits: 5-4, 2.87 ERA (84 2/3 IP, 27 ER), 11 HR, .221 opponent batting average (OBA) in 14 starts

Giolito (7-11, 4.45 ERA) makes his 28th start. He has a 1.28 WHIP, 3.3 BB/9 and 9.7 K/9 in 153 2/3 innings for the Chicago White Sox and Angels.

  • Last start (with Angels): Loss, 5 2/3 IP, 5 ER, 4 H (3 HR), 4 BB, 6 K in a 6-4 road loss vs. the Philadelphia Phillies last Monday
  • 2023 home splits: 4-3, 2.53 ERA (74 2/3 IP, 21 ER), 9 HR, .186 OBA in 12 starts

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Twins at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:02 a.m. ET.

  • Moneyline (ML): Twins -140 (bet $140 to win $100) | Guardians +115 (bet $100 to win $115)
  • Run line (RL)/Against the spread (ATS): Twins -1.5 (+125) | Guardians +1.5 (-155)
  • Over/Under (O/U): 8 (O: -115 | U: -105)

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Twins at Guardians picks and predictions

Prediction

Guardians 4, Twins 3

Moneyline

The GUARDIANS (+115) are solid short ‘dogs at home in this crucial series opener.

After pulling the plug on a playoff push in late July and trading RHP Aaron Civale to the Tampa Bay Rays, the Guardians have re-engaged in the playoff race after treading water and staying afloat in August. Giolito is an innings eater who will try to help Cleveland get over the hump.

Run line/Against the spread

The GUARDIANS +1.5 (-155) are a decent play on the run line at a rather moderate and reasonable price if you’d like a little insurance.

Cleveland has got the better of the Twins in 6 of 10 meetings this season, and Giolito has had great home splits in his previous 2 stops.

Over/Under

UNDER 8 (-105) is the lean, but play a half-unit at most.

The Guardians have cashed the Under in 4 of the past 5 games, including the final 2 contests of the Minnesota series in the Twin Cities earlier in the week.

It’s been all about the Over for the Twins lately, but the Under has connected in 5 of the past 6 meetings with the Guardians.

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Minnesota Twins at Cleveland Guardians odds, picks and predictions

Analyzing Sunday’s Minnesota Twins at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

The Minnesota Twins (19-15) and Cleveland Guardians (15-18) close out a 3-game set at Progressive Field Sunday. First pitch is at 1:40 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Twins vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1

The Twins have stalled of late, going 5-5 over the last 10 and 9-11 over the last 20 games. Runs have been hard to come by as they have plated just 3.6 per game over the last 5 games.

The Guardians snapped a 3-game losing streak with the 4-3 win Saturday. They improved to 11-2 when they score 4 or more runs. Their 17 one-run games are the most in the majors, to which they are 8-9. Cleveland is just 5-9 at home this year.

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Twins at Guardians projected starters

RHP Joe Ryan vs. RHP Cal Quantrill

Ryan (5-0, 2.37 ERA) makes his 7th start. He has a league-leading 0.76 WHIP, 1.4 BB/9 and 10.2 K/9 in 38 2/3 IP.

  • Last start Tuesday vs. Chicago White Sox: 6 IP, 0 ER, 1 H, 2 BB, 7 K
  • Last 5 GS vs. Guardians: 3-0, 1.42 ERA, 0.69 WHIP, 26 K in 31 2/3 IP

Quantrill (1-2, 4.73 ERA) makes his 7th start. He has a 1.49 WHIP, 2.5 BB/9 and 4.7 K/9 in 32 1/3 IP.

  • Last start Monday vs. New York Yankees: 7 1/3 IP, 2 ER, 6 H, 1 BB, 2 K
  • Last 5 GS vs. Minnesota: 4-0, 2.20 ERA, 1.19 WHIP, 21 K in 32 2/3 IP

Twins at Guardians odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:20 a.m. ET.

  • Moneyline (ML): Twins -135 (bet $135 to win $100) | Guardians +110 (bet $100 to win $110)
  • Run line (RL)/Against the spread (ATS): Twins -1.5 (+125) | Guardians +1.5 (-155)
  • Over/Under (O/U): 8.5 (O: -115 | U: -105)

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Twins at Guardians picks and predictions

Prediction

Twins 4, Guardians 2

Moneyline

The Twins are 2-10 in the last 12 meetings and 2-7 in the last 9 in Cleveland. But this is a Twins team on the come up. Ryan has quietly been one of the better starters in the AL. Cleveland doesn’t boast much of a home-field advantage with a 5-9 mark on the season.

Take the TWINS -135.

Run line/Against the spread

The Twins’ last 9 victories have been of the multiple-run variety. They have really been stingy, ranking 3rd in runs/9 (3.66), 3rd in OBA (.219), 2nd in OPS allowed (.633) and 2nd in pitcher K’s (9.87). Conversely, Cleveland scores the 3rd-fewest runs/9 at 3.62.

Take the TWINS -1.5 (+125).

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Over/Under

Cleveland is 1-9 O/U over the last 10, and rain is in the forecast Sunday. The Under is 12-4 in the last 16 meetings in Cleveland and 6-2 in the last 8 meetings overall. The Under is 5-0 in the Guardians’ last 5 divisional games, last 5 against a righty and last 5 at home against a righty. The Twins have cashed Unders in 4 of 7.  So this 8.5 looks like 18.5.

Take the UNDER 8.5 (-105).

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