Minnesota Twins at Cleveland Guardians odds, picks and predictions

Analyzing Saturday’s Minnesota Twins at Cleveland Guardians odds and lines, with MLB expert picks, predictions and best bets.

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The Cleveland Guardians (28-17) welcome the Minnesota Twins (24-20) to Progressive Field Saturday. First pitch in the 2nd game of the 3-game series is set for 6:10 p.m. ET. Let’s analyze FanDuel Sportsbook’s lines around the Twins vs. Guardians odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 1-0

The Guardians won the first game of the series 3-2, closing as -125 favorites. They failed to cover as run-line favorites, but they are still 3-2 against the spread (ATS) over their last 5 games. Cleveland is the 3rd-best team in MLB at home with a 13-6 record.

The Twins have struggled as of late, losing 4 straight games and going 1-3 ATS in that stretch. They were swept by the New York Yankees in their last series but were 5-2 over the 2 series prior. Minnesota is 13-9 on the road.

Twins at Guardians projected starters

RHP Bailey Ober vs. LHP Logan Allen

Ober (4-1, 3.77 ERA) makes his 9th start. He has a 0.88 WHIP, 1.7 BB/9 and 9.4 K/9 in 43 innings.

  • Last start: Win, 6 1/3 IP, 0 ER, 1 H, 0 BB, 10 K in 5-1 road win over Toronto Blue Jays May 11
  • 2024 road splits: 3-1, 4.67 ERA (27 IP, 14 ER), 22 H, 4 HR, 4 BB, 25 K in 5 starts
  • Career vs. Guardians: 1-1, 1.29 ERA (28 IP, 4 ER), 0.75 WHIP, 6.8 K/9 in 5 starts

Allen (4-2, 5.56 ERA) makes his 10th start. He has a 1.50 WHIP, 3.0 BB/9 and 7.1 K/9 in 45 1/3 innings.

  • Last start: Win, 6 IP, 0 ER, 6 H, 1 BB, 3 K in 7-0 road win over Chicago White Sox Sunday
  • 2024 home splits: 1-0, 9.87 ERA (17 1/3 IP, 19 ER), 25 H, 6 HR, 8 BB, 14 K in 4 starts
  • Career vs. Twins: 1-0, 3.09 ERA (11 /23 IP, 4 ER), 1.54 WHIP, 5.4 K/9 in 2 starts

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Twins at Guardians odds

Provided by FanDuel Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 10:05 a.m. ET.

  • Moneyline (ML): Twins -118 (bet $118 to win $100) | Guardians +100 (bet $100 to win $100)
  • Run line (RL)/Against the spread: Twins -1.5 (+146) | Guardians +1.5 (-178)
  • Over/Under (O/U): 7.5 (O: +102 | U: -124)

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Twins at Guardians picks and predictions

Prediction

Twins 4, Guardians 3

Moneyline

BET TWINS (-118).

The Twins have been a strong side with Ober on the mound, and the opposite can be said of Allen. In Allen’s last 3 starts, the Guardians have given up 19 runs and gone 1-2. Ober has allowed 2 or fewer ER in 6 of his last 7 starts.

Minnesota is 17-10 straight up as a favorite and did have a 12-game win streak earlier in the season. With a strong starting option on the mound and success as a favorite, back TWINS (-118).

Run line/Against the spread

PASS.

There’s just no value on the run line here. The Twins are too risky as favorites, while the Guardians are far too expensive as run-line underdogs.

Over/Under

LEAN UNDER 7.5 (-124).

The Twins have gone Under in 5 straight games and struggled immensely on offense, scoring 2 or fewer in 4 straight. Allen’s recent issues could aid Minnesota, but it still hasn’t batted well as of late.

The Guardians have gone Under in 5 of their last 6 games. They are 4-8 O/U in their last 12 games. Given those recent trends, bet UNDER 7.5 (-124).

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