The Florida State Seminoles (2-0, 0-0 ACC) and the Louisville Cardinals (1-1, 0-1 ACC) meet Friday at Cardinal Stadium. Kickoff is scheduled for 7:30 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook‘s lines around the Florida State vs. Louisville school odds, and make our expert college football picks and predictions.
The Seminoles picked up a 47-7 win over Duquesne in the Week 0 opener, before beating LSU 24-23 on a neutral field in New Orleans Saturday. The Seminoles allowed the game-tying touchdown with zeroes on the clock to end regulation but blocked the extra point that was required to force overtime. Twitter exploded. The end.
The Cardinals were humbled 31-7 on the road against Syracuse in the ACC opener, so it is trying to avoid an 0-2 hole in conference play. Louisville did rebound with a strong defensive effort in a 20-14 road win at UCF last week.
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Florida State at Louisville odds
Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 6:24 a.m. ET.
- Money line (ML): Florida State -145 (bet $145 to win $100) | Louisville +122 (bet $100 to win $122)
- Against the spread (ATS): Florida State -2.5 (-117) | Louisville +2.5 (-103)
- Over/Under (O/U): 56.5 (O: -115 | U: -105)
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Florida State at Louisville picks and predictions
Prediction
Louisville 31, Florida State 28
Money line
LOUISVILLE (+122) didn’t look very good in its first game, getting drilled by Syracuse in the opener. However, the defense was sound at UFC, and QB Malik Cunningham got back on track with a long scoring run to get the Cardinals over the hump. Cunningham has yet to toss a touchdown pass, but Louisville should be a lot more comfortable in its home opener.
Against the spread
LOUISVILLE +2.5 (-103) is a better play on the money line if you like them, but the option to get a couple of points of insurance is there. However, taking the Cardinals with less than 3 points is such a small amount. The Seminoles are just 1-5 ATS in the past 6 meetings in this series, and the home team is 5-2 ATS across the past 7 meetings.
Over/Under
The OVER 56.5 (-115) is the lean here. The Under is 2-0 for FSU so far and has cashed in 6 of its last 7 on the road, but the Over is 6-2 in the previous 8 meetings between these teams and 4-0 in the past 4 meetings in Louisville.
The Cardinals have managed just 13.5 PPG through 2 games, but this offense is certainly due. The Over is 11-5 in their last 16 home games, too, so expect a much better performance Friday — especially through the air.
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