The Chicago White Sox (1-2) visit the division rival Cleveland Indians (2-1) Monday at Progressive Field for a 7:10 p.m. ET first pitch. We analyze the White Sox-Indians MLB betting odds and picks, with betting advice and tips around the matchup.
White Sox at Indians: Projected starting pitchers
RHP Dylan Cease vs. RHP Aaron Civale
Cease posted a dismal 4-7 record, 5.79 ERA and 1.55 WHIP across 73 innings over 14 starts in 2019, his rookie year.
- The right-hander was a little better on the road than at home last season. He went 2-3 with a 4.89 ERA over 38 2/3 innings in seven road starts, while finishing 2-4 with a 6.82 ERA across 34 1/3 innings in seven home outings.
- Cease made just one start in 2019 against the Indians, allowing four earned runs on four hits and two walks with a career-high 11 strikeouts across 6 2/3 innings in a no-decision Sept. 3, 2019 in Cleveland.
Civale posted a 3-4 record with a 2.34 ERA, 1.04 WHIP and 46 strikeouts over 57 2/3 innings across 10 starts last season, also his rookie campaign.
- Civale was nearly untouchable at home last year, going 2-1 with a 1.09 ERA and .195 opponent batting average across 24 2/3 innings in four starts.
- Civale went 1-1 with a 5.40 ERA and .313 opponent batting average while serving up two homers in two starts against the White Sox in 2019.
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White Sox at Indians: Key injuries
(List of injuries around the league)
White Sox
- OF Eloy Jimenez (head) questionable
- 2B Nick Madrigal (head) questionable
- OF Nomar Mazara (illness) out
Indians
- CF Delino DeShields (COVID-19 symptoms) out
- OF Tyler Naquin (toe) out
White Sox at Indians: Odds, lines, picks and betting tips
MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated Monday at 5:40 a.m. ET.
Prediction
Indians 6, White Sox 4
Moneyline (ML)
The INDIANS (-129) are a solid value at home with Civale on the bump, as he was money at home last season. On the flip side, Cease was rather shaky, although he was much better on the road than at home. Still, Chicago’s pitching was shaky in its opening series against the Minnesota Twins, losing two out of three games while coughing up 27 total runs. Look for Cleveland’s offense to take advantage.
New to sports betting? A $10 bet on the Indians (-129) to win straight up nets a return of just $7.75 if they do so.
Run line/Against the spread (ATS)
The INDIANS (-1.5, +145) are worth a small-unit wager against Cease. Plus, the White Sox have won just six of their past 20 games at Progressive Field, so the home side is definitely the play.
Over/Under (O/U)
OVER 9.5 (-110) is worth a look, but don’t get crazy. Civale was untouchable at home in 2019, while Cease was better on the road than at home. However, Chicago’s pitching staff was tattooed for 27 runs (nine runs per game) in the first series against the Twins. After a slow start, totaling four runs in the first two games, the Indians racked up nine in their series-clinching win on Sunday against the Kansas City Royals.
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