Houston Texans vs. Tennessee Titans odds predictions pick betting line spread

The Houston Texans (1-12-1) are set to face the Tennessee Titans (7-7) on Saturday in Week 16 at Nissan Stadium. Kickoff is scheduled for 2:02 p.m. ET (CBS). Below, we analyze Tipico Sportsbook’s lines around the Texans vs. Titans odds, and make our expert NFL picks and predictions.

The Texans were defeated 30-24 by the Kansas City Chiefs in overtime in Week 15, but covered as 14.5-point underdogs. Despite losing 9 straight games, Houston has played Kansas City and the Dallas Cowboys close in the last 2 weeks.

The Titans suffered a 17-14 loss to the Los Angeles Chargers in Week 15 to push as 3-point underdogs. Tennessee has lost 4 games in a row and is now only 1 game ahead of the Jacksonville Jaguars in the AFC South.

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Texans at Titans odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 12:59 p.m. ET.

Moneyline (ML): Texans +145 (bet $100 to win $145) | Titans -170 (bet $170 to win $100)
Against the spread (ATS): Texans +3 (-103) | Titans -3 (-117)
Over/Under (O/U): 34 (O: -110 | U: -110)

Texans at Titans key injuries

Texans

WR Nico Collins (foot) out
WR Brandin Cooks (calf) questionable
OL Kenyon Green (ankle) out
OL Justin McCray (hamstring) questionable
WR Chris Moore (foot) questionable
DB Steven Nelson (foot, knee) questionable

Titans

CB Tre Avery (concussion) questionable
OL Aaron Brewer (rib) questionable
WR Treylon Burks (concussion) questionable
OL Nate Davis (ankle) out
CB Kristian Fulton (groin) out
S Amani Hooker (knee) questionable
C Ben Jones (concussion) out
CB Terrance Mitchell (hamstring) out
OL Nicholas Petit-Frere (ankle) questionable
OL Dillon Radunz (knee) out
QB Ryan Tannehill (ankle) out

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Texans at Titans picks and predictions

Prediction

Titans 24, Texans 20

Moneyline

PASS.

The current odds for Tennessee (-170) to win straight up aren’t worth taking as the Titans will have rookie QB Malik Willis under center.

Against the spread

TITANS -3 (-117) is where I’m leaning in this game despite the loss of Tannehill. Tennessee still has RB Derrick Henry, who has rushed for 200-plus yards and multiple TDs in 4 straight matchups against Houston.

The Titans are 6-1 ATS in their last 7 games against a team with a losing record. The home team is also 9-4 ATS in the last 13 meetings between the Texans and the Titans.

Over/Under

Even with both of these teams not having high-flying offenses, OVER 34 (-110) is an intriguing bet in this contest. Henry could score nearly half or more than half of the points needed to hit the Over while the Texans have been more competitive in recent weeks.

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The Minnesota Vikings and New Orleans Saints came through for us and covered as underdogs in Week 10, while the Las Vegas Raiders fell far short.

That makes it eight winning weeks out of 10 here this season for an overall against-the-spread (ATS) record of 22-8 with 18 outright winners.

Here are our NFL underdog ATS picks and predictions of Week 11.

NFL underdog predictions: Week 11

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Wednesday at 5:06 p.m. ET.

Houston Texans +9.5 (+100) at Tennessee Titans

The AFC-leading Titans (8-2 straight up, 7-3 ATS) have won six in a row and covered in five of their last six with the last five coming against 2020 playoff teams.

But with a road game at the suddenly surging New England Patriots looming in Week 12, this is prime letdown spot for Tennessee.

Take the TEXANS +9.5 (+100) and QB Tyrod Taylor and to keep things close in a division game coming off a bye.

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New Orleans Saints +2.5 (-105) at Philadelphia Eagles

Is the wrong team favored here? Here’s the case:

The Saints are a league-best 11-3 SU and 12-2 ATS as an underdog since 2018, including 3-1 and 4-0, respectively, this season.

The Eagles are 0-4 SU and 1-3 ATS at home this season.

We’ll bank on the league’s best run defense negating the league’s third-best rushing attack and go with the SAINTS +2.5 (-105), hitting the +110 money line as well.

Also see: All Week 11 odds and lines

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Indianapolis Colts +7.5 (-117) at Buffalo Bills

This is a rematch of last January’s AFC Wild Card Game won 27-24 by the host Bills.

Buffalo didn’t cover as a touchdown favorite that day and has failed to cover in three of its previous four games this season heading into Sunday’s meeting.

Indy has won four of its last five – losing only to the Titans 34-31 in overtime in Week 8 – and figures to keep things tight in Orchard Park. Take the COLTS +7.5 (-117) catching more than a TD.

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