Best NFL underdog picks and predictions for Week 12

Analyzing NFL Week 12 betting odds and lines, with expert predictions and picks of the 3 best underdogs to cash in on.

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Thanksgiving Day means an accelerated start to Week 12, so before you sit down for some turkey and good fixings, it’s time to look at some underdog picks for the week.

Week 11 wasn’t a good week for the underdog. Only 3 underdogs — the Tennessee TitansDetroit Lions and Las Vegas Raiders — won outright, although 6 underdogs covered the spread in their losses, including the Indianapolis Colts and Carolina Panthers.

Below, we analyze Tipico Sportsbook’s NFL odds and lines, and tab the best NFL Week 12 underdog bets to cash in on among SportbookWire’s NFL expert picks and predictions.

All 3 of our best underdog picks from Week 11 hit — the Bears and Chargers covered the spread and the Raiders won outright — bringing our season record to 16-17.

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NFL underdog predictions: Week 12

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Thursday at 11:16 a.m. ET. All games Sunday and ET unless noted.

Buffalo Bills at DETROIT LIONS +9.5 (-106) – Thursday, 12:30 p.m. ET (CBS)

The Lions have won 3 straight games and, of their 6 losses this season, they have lost by double digits only twice. Detroit has scored at least 30 points in 5 of its games and has a 6th with 27 points. It has proven the offense can keep games close.

The Bills have 4 double-digit wins, but 2 came in the first 2 weeks.

Buffalo is 5-4-1 ATS and Detroit is 6-4 ATS.

Check out: All Week 12 odds and lines

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

HOUSTON TEXANS +13 (-108) at Miami Dolphins – 1 p.m. (CBS)

The Texans have lost by more than 13 points only once this season and the Dolphins have only won by more than 13 points once.

The Texans are 1-8-1 but 4-5-1 ATS. Meanwhile, the Dolphins are 7-3 straight up and 5-5 ATS.

Play our free daily Pick’em Challenge and win! Play now!

Los Angeles Chargers at ARIZONA CARDINALS (+145) – 4:05 (CBS)

The Cardinals are expected to get QB Kyler Murray and WR Marquise Brown back this week. The Arizona offense works best when it can run the ball, which it does much better when Murray plays. The Chargers are awful against the run, ranking 30th in rushing yards allowed per game (148.4) and last in yards per carry allowed (5.5).

The Cardinals are 4-0 when opponents rush for fewer than 100 yards and 0-6 when they rush for 100 or more. The Chargers have only passed 100 rushing yards as a team twice this season.

More NFL Week 12 picks and predictions

Want action on any of these NFL underdogs or other matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

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NFL Week 12 parlay: Let’s make some money

Analyzing NFL Week 12 betting odds and lines, with predictions and picks for the best parlay bet to make.

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While it’s the season to stuff ourselves with fixings of the Thanksgiving holiday, let’s stuff our pockets with some money.

After looking at Tipico Sportsbook’s NFL Week 12 odds, here is the latest “Let’s make some money” NFL parlay bet to cash in on among SportbookWire’s NFL expert picks and predictions.

This is a difficult week for a parlay. With 3 games being played on Thanksgiving, it limits the number of plays available on Sunday if we don’t include any Thursday contests. No worries though. We are still going to choose the best plays to make some money for you.

Tossing out the Thursday slate, we can’t play the Buffalo Bills, but the Seattle Seahawks and Miami Dolphins are back off byes. So, there are still some solid teams ready to cash in for us. Let’s do it!

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Live games, analysis and more 7 days a week: Get ESPN+

NFL Week 12: Let’s make some money parlay

Odds provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated on Wednesday at 9:37 p.m. ET. All games Sunday and ET unless noted.

Leg 1: Buccaneers at Browns UNDER 43 (-109) – 1 p.m. (FOX)

While the Over is 7-2-1 in Cleveland games this season, coach Kevin Stefanski will deploy a ground attack behind RBs Nick Chubb and Kareem Hunt vs. Tampa Bay.

In last week’s 31-23 loss to Buffalo, Cleveland ran 33 times for 171 yards. The plan will be the same this Sunday, while Tampa Bay will also look to run the ball — essentially running the clock — especially if the weather is cold, which the forecast calls for. With Chubb and Hunt for Cleveland and RBs Leonard Fournette and Rachaad White for Tampa Bay, this will be a game of long, time-filled drives.

This feels like another game for the Buccaneers where the Under 43 hits, something which has taken place in 8 of Tampa Bay’s 10 games this season.

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

Leg 2: Bears at Jets OVER 38 (-109) – 1 p.m. (FOX)

Chicago has put up at least 24 points in each of its last 4 games — all losses. After giving up at least 31 in 3 of those games, the Atlanta Falcons scored 27 against the Bears defense last Sunday.

QB Justin Fields is back at practice and hopes to play Sunday after suffering a separated shoulder on the final drive last week vs. Atlanta. His participation in the Jets game is key. His running ability will be a crucial factor as the Jets are tied for 4th in the NFL with 32 sacks. Fields will be forced to use his legs and get the ball out early playing behind a shaky offensive line.

The Jets have officially made the change away from QB Zach Wilson. Coach Robert Saleh decided to bench the No. 2 overall pick of the 2021 NFL Draft and start QB Mike White vs. the Bears. This can only help New York’s offense as White showed last season in 3 starts, including during a win over the eventual AFC champion Cincinnati Bengals.

Jets CB Sauce Gardner is the favorite for Defensive Rookie of the Year — listed at -200 by Tipico Sportsbook. But with Chicago not passing the ball, this will limit Gardner’s impact Sunday. If the Bears can sustain a run game, they will score, and with the Bears defense being bad, the Jets will score, too. The O/U of 38 is far too low.

Play our free daily Pick’em Challenge and win! Play now!

Leg 3: Texans at DOLPHINS -13 (-112) – 1 p.m. (CBS)

Coming off a bye week, the Dolphins are going to be fired up to get out on the field.

Currently tied for 1st in the AFC East, Miami needs to keep winning to remain ahead of the Bills (7-3), who they hold the head-to-head tiebreaker over. WR Tyreek Hill is having an incredible season, while WR Jaylen Waddle is becoming one of the best WR 2’s in the NFL. QB Tua Tagovailoa has completely transformed under coach Mike McDaniel and with Hill at wideout.

Along with the passing game showing up, the run game with RBs Raheem Mostert and Jeff Wilson has come alive, too. Wilson has rushed for 170 yards and 1 TD on 26 carries in 2 games since joining the Dolphins after being acquired in a trade from the San Francisco 49ers. He has brought a balance to the backfield, which McDaniel — who learned under Kyle Shanahan — needed to allow the pass game to flourish.

While the defense for Miami is not a strength, especially with CB Byron Jones out and CB Xavien Howard banged up, it did get stronger at the trade deadline. The addition of LB Bradley Chubb provides help in a much-needed run defense, which should be critical against the Texans as RB Dameon Pierce is really their only threat on offense.

Houston QB Davis Mills, who started off OK in 2021, has not progressed in 2022 and coach Lovie Smith has not committed to him as the starter moving forward. If Mills gets benched, QB Kyle Allen will take over.

Either way, Miami is having a special season and Houston (1-8-1) owns the league’s worst record and is looking at winning the No. 1 draft pick in next summer’s draft.

Laying 13 points is a lot, but the Dolphins should still be favored by more. TAKE MIAMI -13 (-112) as the 3rd leg of our parlay.

Parlay payout: Bet $10 to win $69.59 (profit $59.59).

Try out the USA TODAY Parlay Calculator.

Leg 4-*: Raiders at SEAHAWKS -3.5 (-112) – 4:05 p.m. (CBS)

*-If you want to add a 4th play to this parlay:

While Las Vegas and Seattle both can score, the Seahawks defense is starting to get better, while the Raiders defense is not.

Coming off a bye week after a 21-16 loss in Germany to Tampa Bay, Seattle returns home and looks to get back on track in a big way. With WRs Tyler Lockett and WR DK Metcalf and RB Kenneth Walker III, QB Geno Smith has played to a pro bowl level under coach Pete Carroll.

The Raiders have been dysfunctional to say the least under coach Josh McDaniel. This will be another mark in the win column for Seattle.

Parlay payout: Bet $10 to win $131.73 (profit $121.73).

More NFL Week 12 picks and predictions

Want action on any of these games or other sports matchups? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire’s official sportsbook partner in CO and NJ. Bet now!

If you’re looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW. Please gamble responsibly.

Follow Dominick Petrillo on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Access more NFL coverage:

BetFTW | TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | ColtsWire | CommandersWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWireTitansWire | VikingsWire | DraftWire | TouchdownWire | ListWire

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