Cleveland Guardians at Boston Red Sox odds, picks and predictions

Analyzing Thursday’s Cleveland Guardians at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Cleveland Guardians (12-6) and Boston Red Sox (10-9) wrap up a 4-game series Thursday. First pitch is scheduled for 1:35 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Guardians vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 2-1

Cleveland won the first 2 games of this series Monday (6-0) and Tuesday (10-7 in 11 innings), but Boston posted a 2-0 victory Wednesday as the Under (8) was never in question.

The Guardians had scored at least 2 runs in each of their first 17 games before Wednesday’s shutout loss. Cleveland had 16 runs in the first 2 outings of this series, and 24 total runs in the 3 games prior to Wednesday night. The Over has a slight 5-3 edge in the past 8 contests for the Guardians.

Boston allowed a season-high 10 runs in Tuesday’s loss, but it recorded a 3rd shutout win in just 19 games. The Under has connected in 5 of the past 6 games for the Red Sox.

Guardians at Red Sox projected starters

RHP Carlos Carrasco vs. LHP Brennan Bernardino

Carrasco (0-1, 3.55 ERA) makes his 4th start of the season. He has a 1.66 WHIP, 6.4 BB/9 and 7.8 K/9 in 12 2/3 innings.

  • Last start: Loss, 4 2/3 IP, 1 ER, 5 H, 5 BB, 2 K in 3-2 home loss to New York Yankees Saturday
  • 2024 road splits: 0-0, 4.50 ERA (8 IP, 4 ER), 7 H, 4 BB, 9 K, .241 opponent batting average (OBA) in 2 starts

Bernardino (0-1, 1.69 ERA) makes his 1st start and 5th appearance of the season. He has a 0.75 WHIP, 3.4 BB/9 and 13.5 K/9 in 5 1/3 innings.

  • Last start: No-decision, 1 IP, 0 ER, 2 H, 0 BB, 2 K as an opener in a 13-1 home loss vs. Toronto Blue Jays on Aug. 6, 2023
  • Career vs. Guardians: 1-1, 1.59 ERA (5 2/3 IP, 1 ER), 3 H, 2 BB, 5 K in 6 relief appearances

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Guardians at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:40 a.m. ET.

  • Moneyline (ML): Guardians +105 (bet $100 to win $105) | Red Sox -125 (bet $125 to win $100)
  • Run line (RL)/Against the spread (ATS): Guardians +1.5 (-185) | Red Sox -1.5 (+150)
  • Over/Under (O/U): 9.5 (O: -105 | U: -115)

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Guardians at Red Sox picks and predictions

Prediction

Guardians 5, Red Sox 4

Moneyline

The GUARDIANS (+105) are worth a look at plus-money as Cleveland looks to get back on track after Wednesday’s shutout loss.

Cleveland has posted an impressive 9-3 road record. The Guardians have lost consecutive road games just once (March 31-April 1) so far this season. They had won 6 road games in a row until Wednesday’s loss.

The Red Sox (-125) have managed just 3 victories in 9 tries at Fenway Park, and that isn’t likely to change with the opener Bernardino on the hill — before he turns it over the bullpen.

Run line/Against the spread

The Red Sox +1.5 (-185) aren’t worth playing. The -185 juice is too much the little insurance of a run and a half.

PASS.

Over/Under

UNDER 9.5 (-115) is a good play in this matinee series finale.

The Under is on a 5-1 run for the Red Sox, including 2-1 in the first 3 games of this series.

For the Guardians, the Over-Under has split 3-3 in the past 6 games. The Under has cashed in 4 of the past 5 games on the road, too.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Cleveland Guardians at Boston Red Sox odds, picks and predictions

Analyzing Wednesday’s Cleveland Guardians at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Cleveland Guardians (12-5) and Boston Red Sox (9-9) play the 3rd contest of a 4-game series Wednesday. First pitch is scheduled for 7:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Guardians vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 2-0 after posting wild 10-7 victory in 11 innings Tuesday as slight underdogs (+106) with Over (8.5) easily cashing

The Guardians have unexpectedly fired out to a 12-5 start, which gives them the best record in baseball at the moment. Their success has been aided by an ability to win on the road as Cleveland is 9-2 away from home, while posting a plus-38 run differential, 2nd-best in the majors behind the equally surprising Kansas City Royals (+39).

The Red Sox have been tripped up in 6 of the past 8 games as the pitching has conceded at least 6 runs in each of the 6 losses. The Under is 4-1 in the past 5, though, as the offense has cobbled together just 3.8 runs per game (RPG), including a pair of shutout losses.

Guardians at Red Sox projected starters

RHP Ben Lively vs. RHP Tanner Houck

Lively (4-7, 5.38 ERA in 2023 with Cincinnati) makes his 1st start of 2024. He had a 1.36 WHIP, 2.5 BB/9 and 8.0 K/9 in 88 2/3 innings last season.

  • Last start: Loss, 4 IP, 13 ER, 13 H (4 HR), 2 BB, 2 K in 20-9 road loss at Chicago Cubs Aug. 1, 2023 for Cincinnati
  • 2023 road splits: 2-5, 5.90 ERA, 50.1 IP, 33 ER, 62 H, 9 BB, 40 K in 6 starts and 5 relief appearances

Houck (2-1, 2.04 ERA) makes his 4th start of the season. He has a 1.19 WHIP, 1.0 BB/9 and 9.7 K/9 in 17 2/3 innings.

  • Last start: Loss, 5 2/3 IP, 7 R (4 ER), 12 H (1 HR), 0 BB, 2 K in 7-0 home setback to Los Angeles Angels Friday
  • Career vs. Guardians: 0-1, 3.52 ERA (15 1/3 IP, 6 ER), 10 H, 4 BB, 14 K in 2 starts and 5 relief appearances

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Guardians at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 2:11 p.m. ET.

  • Moneyline (ML): Guardians +110 (bet $100 to win $110) | Red Sox -130 (bet $130 to win $100)
  • Run line (RL)/Against the spread (ATS): Guardians +1.5 (-175) | Red Sox -1.5 (+145)
  • Over/Under (O/U): 8.5 (O: -115 | U: -105)

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Guardians at Red Sox picks and predictions

Prediction

Red Sox 7, Guardians 4

Moneyline

The RED SOX (-130) are a good play as moderate favorites against the surprising Guardians (+110).

After the season-ending injury to RHP Shane Bieber, and a doubleheader with the New York Yankees, the Guardians had to get creative with the starting rotation. Lively gets the nod here in his 1st start — coming off the 10-day injury list due to an illness — to make his Cleveland debut. It might be a bit rocky.

Run line/Against the spread

The RED SOX -1.5 (+140) are worth a look on the run line, as they try to turn things around and avoid slipping under .500. The Guardians have won the first 2 in the set, but they turn to the unproven Lively who was pounded last season, pitching for the Reds. He is likely to show some rust since it’s his 1st start of 2024, and the expectation is that Boston’s offense jumps on him early.

Divvy up 1½ UNITS between the 2 wagers — Boston ML and Boston RL — as you see fit.

Over/Under

OVER 8.5 (-115) is the play here with Lively being the driving factor.

He hasn’t pitched in a meaningful game since last summer — while with another organization. Expect nerves to be rampant as he debuts for his new team in a tough pitcher’s park.

In addition, while Houck pitched well in his first 3 starts, he is coming off a rough outing against the Halos, so the Guardians should be able to get to him.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Cleveland Guardians at Boston Red Sox odds, picks and predictions

Analyzing Tuesday’s Cleveland Guardians at Boston Red Sox odds and lines, with MLB expert picks, predictions and best bets.

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The Cleveland Guardians (11-5) and Boston Red Sox (9-8) square off for the 2nd time in a 4-game series on Tuesday. First pitch is scheduled for 7:10 p.m. ET (ESPN). Let’s analyze BetMGM Sportsbook’s lines around the Guardians vs. Red Sox odds and make our expert MLB picks and predictions for the best bets.

Season series: Guardians lead 1-0 after a 6-0 Patriot’s Day win in Boston, cashing as an underdog (+140) while the Under (9.5) hit

The Guardians have won 2 straight as an underdog after going 1-3 in the previous 4 outings. As an underdog, Cleveland is 8-1 on the run line, winning 6 of those games outright. The Over has cashed at a 4-2 pace in the past 6 contests.

The Red Sox have been shut out in 2 of the past 4 games, bookending a pair of victories against the Los Angeles Angels over the weekend. The Under has cashed in 4 in a row, too.

Cleveland has won 3 straight in the series, while the Under and Over has alternated in each of the past 7 meetings since April 28, 2023.

Guardians at Red Sox projected starters

RHP Tanner Bibee vs. RHP Garrett Whitlock

Bibee (1-0, 5.93 ERA) makes his 4th start. He has a 1.83 WHIP, 5.3 BB/9 and 9.9 K/9 in 13 2/3 innings.

  • Last start: No-decision, 4 1/3 IP, 5 ER, 6 H, 3 BB, 2 K in 7-6 win in 10 innings last Wednesday vs. Chicago White Sox
  • Last road start: Win, 5 1/3 IP, 1 ER, 5 H (1 HR), 0 BB, 9 K in 4-2 win vs. Minnesota Twins April 4

Whitlock (1-0, 1.26 ERA) makes his 4th start. He has a 1.19 WHIP, 3.8 BB/9 and 10.1 K/9 in 14 1/3 innings.

  • Last start: No-decision, 5 IP, 1 ER, 4 H (1 HR), 2 BB, 4 K in 9-4 loss in 10 innings Thursday vs. Baltimore Orioles
  • Career vs. Guardians: 1-0, 2.84 ERA, 6.1 IP, 2 ER, 2 H, 1 BB, 7 K, 2 SV in 4 relief appearances

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Guardians at Red Sox odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:26 a.m. ET.

  • Moneyline (ML): Guardians -105 (bet $105 to win $100) | Red Sox -115 (bet $115 to win $100)
  • Run line (RL)/Against the spread (ATS): Guardians -1.5 (+155) | Red Sox +1.5 (-190)
  • Over/Under (O/U): 9 (O: $100 | U: -120)

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Guardians at Red Sox picks and predictions

Prediction

Red Sox 5, Guardians 3

Moneyline

The RED SOX (-115) are a decent play Tuesday night at Fenway Park, as Boston looks for the bounce back.

The Guardians (-105) were sharp in a 6-0 win in matinee action on Monday, but look for the Boston bats to come alive against Bibee.

Run line/Against the spread

The Red Sox +1.5 (-190) will cost you nearly 2 times your potential return, and that’s too expensive if you require a little bit of insurance and you can’t back Boston straight up.

PASS, and just play the moneyline.

Over/Under

UNDER 9 (-120) is the lean, but go with a half-unit play at most.

The Under has a 5-3 edge in the past 8 meetings since July 28, 2022. The Under also has a 5-4 edge in the past 9 games for the Guardians, while cashing in each of the past 3 outings on the road.

For the Red Sox, the Under has cashed in 4 straight games, averaging 3.0 runs per game (RPG), while allowing 4.8 RPG.

Play our free daily Pick’em Challenge and win! Play now!

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Kevin J. Erickson on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Additional MLB coverage:
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