San Francisco Giants at Houston Astros odds, picks and predictions

Analyzing Tuesday’s San Francisco Giants at Houston Astros odds and lines, with MLB expert picks, predictions and best bets.

The San Francisco Giants (11-17) and Houston Astros (16-13) play the middle game of a 3-game set at Minute Maid Park Tuesday. First pitch is at 8:10 p.m. ET. Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Astros odds and make our expert MLB picks and predictions for the best bets.

Season series: Houston leads 1-0

The roof caved in on the Giants’ bullpen Monday as they lost 7-3 after allowing 5 runs in the 7th inning with the game tied 2-2. 1B LaMont Wade Jr. homered for the 3rd straight game. He’s riding a 6-game hitting streak and is hitting .364 with 4 homers during that stretch.

Houston had to navigate 9 innings with its bullpen after RHP Luis Garcia (elbow) left the game after 8 pitches. They allowed just 3 ER on 4 H and struck out 9. However, that may have an effect over the course of the rest of the series.

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Giants at Astros projected starters

RHP Anthony DeSclafani vs. RHP Hunter Brown

DeSclafani (2-1, 2.70 ERA) makes his 6th start. He has a 0.93 WHIP, 0.9 BB/9 and 8.1 K/9 through 30 IP.

  • Last start vs. the St. Louis Cardinals Wednesday: 6 IP, 2 ER, 6 H, 1 BB, 6 K
  • 1 career start vs. Houston in 2019: 5 1/3 IP, 1 ER, 6 H, 1 BB, 4 K

Brown (3-0, 2,37 ERA) makes his 6th start. He has a 1.06 WHIP, 3.0 BB/9 and 9.5 K/9 through 30 1/3 IP.

  • Has thrown 7 IP with 0 ER in 3 of last 4 starts
  • Has 5 K or more in each start this year

Giants at Astros odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:37 p.m. ET.

  • Moneyline (ML): Giants +155 (bet $100 to win $155) | Astros -190 (bet $190 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-130) | Astros -1.5 (+105)
  • Over/Under (O/U): 8 (O: -110 | U: -110)

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Giants at Astros picks and predictions

Prediction

Astros 6, Giants 4

Moneyline

Brown has only allowed an earned run in 2 of his 5 starts, and the Astros need length from him Tuesday. He has yet to give up a homer this season, and that’s what the Giants do best. San Francisco is 3rd in MLB with 1.74 HR/game but lost OF Mike Yastrzemski (hamstring) and SS Brandon Crawford (calf) to the IL Monday, and the Astros should have enough to take down the thin club.

Since Brown induces strikeouts, and the Giants whiff the most (10.79/game), take the parlay of ASTROS ML+BROWN 5 K (-120) at a much more reasonable price than the -190 ML.

Run line/Against the spread

The Astros’ pen threw the entire Monday game, and it’s a lot to ask to hit the RL with just a +105 incentive.

PASS.

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Over/Under

This one is a wild card. The Giants are 4-5-1 O/U over the last 10 games, and Houston is 4-6. However, it’s 79 degrees with an 8-mph gust toward the Crawford Boxes in left-center field. DeSclafani has given up a homer in 3 straight starts, and 4 have left the park overall. It’s not a sure thing, but I’ll lean OVER 8 (-110).

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San Francisco Giants at Houston Astros odds, picks and predictions

Analyzing Monday’s San Francisco Giants at Houston Astros odds and lines, with MLB expert picks, predictions and best bets.

The San Francisco Giants (11-16) begin a 3-game series against the Houston Astros (15-13) on Monday at Minute Maid Park. First pitch is scheduled for 8:10 p.m. ET (FS1). Let’s analyze BetMGM Sportsbook’s lines around the Giants vs. Astros odds and make our expert MLB picks and predictions for the best bets.

Season series: First meeting since the 2021 season (Giants won 2-1)

The Giants lost 6-4 to the San Diego Padres on Sunday as they dropped both games in the Mexico City series. San Francisco is on a 3-game losing streak following a 5-game winning streak.

The Astros beat the Philadelphia Phillies 4-3 on Sunday to end a 2-game losing streak. Houston has won 7 of its last 10 games.

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Giants at Astros projected starters

RHP Ross Stripling vs. RHP Luis Garcia

Stripling (0-1, 6.89 ERA) makes his 3rd start. He has a 1.60 WHIP, 2.9 BB/9 and 8.0 K/9 in 15 2/3 IP.

  • Has given up 6 HR in 5 appearances (2 starts)
  • Has a 1-1 record with a 4.97 ERA, 1.82 WHIP, and 6.4 K/9 in 3 career starts against the Astros

Garcia (2-2, 4.00 ERA) makes his 6th start. He has a 1.26 WHIP, 3.3 BB/9 and 10.3 K/9 in 27 IP.

  • Allowed a combined 0 ER on 5 H with 3 BB and 16 K in his last 2 starts after giving up 12 ER on 19 H in his 1st 3 starts
  • Has 7-plus K’s in his last 3 starts and has won back-to-back starts

Giants at Astros odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:26 a.m. ET.

  • Moneyline (ML): Giants +155 (bet $100 to win $155) | Astros -190 (bet $190 to win $100)
  • Run line (RL)/Against the spread (ATS): Giants +1.5 (-125) | Astros-1.5 (+105)
  • Over/Under (O/U): 8.5 (O: -110 | U: -110)

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Giants at Astros picks and predictions

Prediction

Astros 5, Giants 2

Moneyline

PASS.

While the Astros are favored to secure the win at home, taking them straight up at nearly -200 odds isn’t worth the risk. That being said, you can pair Garcia’s strikeouts and Houston’s moneyline for decent odds in this contest.

Run line/Against the spread

ASTROS -1.5 (+105) is the pick in this contest after the Giants travel to Houston after playing in high-altitude Mexico City the previous 2 days. On top of that, Stripling has struggled with a whopping 15.4% barrel percentage and a 117.8 mph max EV (exit velocity).

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Over/Under

UNDER 8.5 (-110) is the ideal bet with Garcia taking the mound for the Astros. Garcia has shut out the Toronto Blue Jays and the Tampa Bay Rays in his last 2 starts.

The Astros are 4-0 to the Under in their last 4 interleague games and 5-0 in their last 5 games overall.

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For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

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Additional MLB coverage:
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