Sunday updates will begin when teams start releasing official pregame inactives and starter information to the league. This is typically around 60-90 minutes prior to the kickoff of their game.
Weather forecasts are courtesy of The Football Database.
Week 5 gameday inactives, weather and notes
KEY GAME-TIME DECISIONS
Early games: WR Zay Jones (active), WR Odell Beckham Jr. (active), RB Justice Hill (active), WR Amon-Ra St. Brown (inactive), RB Jahmyr Gibbs (inactive), RB Rhamondre Stevenson (active), RB Saquon Barkley (inactive)
Afternoon games: WR Tee Higgins (inactive)
Sunday night:
Monday night: WR Davante Adams, RB Aaron Jones
Jacksonville Jaguars at Buffalo Bills in London (9:30 a.m. ET)
Kickoff Weather: 72 degrees, cloudy
Jaguars
Inactives: LB Devin Lloyd, WR Elijah Cooks, CB Christian Braswell and OG Cole Van Lanen
Lineup notes: WR Zay Jones (knee) was limited all week and deemed questionable but will play. LT Cam Robinson was activated after serving a four-game suspension for violating the league’s performance-enhancing drug policy. LB Devin Lloyd (thumb) is out.
Bills
Inactives: OG Alec Anderson, DT Poona Ford, OT Germain Ifedi, DE Gregory Rousseau, CB Christian Benford, S Damar Hamlin and DE Shaq Lawson
Lineup notes: TE Dawson Knox (quadriceps) made it back for a full session Friday. He’ll continue to play through the injury. RB Damien Harris (neck) was limited Wednesday but practiced fully the rest of the week. He’ll go. LB Von Miller (knee) will make his season debut, whereas CB Tre’Davious White (Achilles) was placed on IR.
Houston Texans at Atlanta Falcons (1:00 p.m. ET)
Kickoff Weather: Dome stadium
Texans
Inactives: RB Dare Ogunbowale, CB Shaquill Griffin, LB Garret Wallow, CB Tavierre Thomas, QB Case Keenum, LB Christian Harris and OT Joshua Jones
Lineup notes: RB Dameon Pierce (knee) had a limited session Wednesday but was all good the rest of the week. He’ll play. WR John Metchie (illness) overcame a questionable tag and is active. RT Tytus Howard was activated from injured reserve, and LT Laremy Tunsil is on the field, too. LB Christian Harris (concussion) is out.
Falcons
Inactives: LB Andre X. Smith, QB Logan Woodside, LB DeAngelo Malone, DT Ta’Quon Graham, DE Joe Gaziano and OG Jovaughn Gwyn
Lineup notes: No injuries of fantasy relevance.
Carolina Panthers at Detroit Lions (1:00 p.m. ET)
Kickoff Weather: Dome stadium
Panthers
Inactives: OT David Sharpe, LB Deion Jones, CB Donte Jackson, RB Raheem Blackshear and S Xavier Woods
Lineup notes: RB Miles Sanders (groin) had a full session Friday and will play.
Lions
Inactives: WR Amon-Ra St. Brown, RB Jahmyr Gibbs, TE James Mitchell, DT Levi Onwuzurike, S Brian Branch and DL Brodric Martin
Lineup notes: WR Amon-Ra St. Brown (abdomen) and RB Jahmyr Gibbs (hamstring) were doubtful and now officially inactive. WR Josh Reynolds (groin) and WR Jameson Williams (activated from suspension) will play, and LT Taylor Decker (ankle) joins them, though S Brian Branch (ankle) is unavailable.
Tennessee Titans at Indianapolis Colts (1:00 p.m. ET)
Kickoff Weather: 54 degrees, cloudy, WNW 10 mph (retractable-roof dome)
Titans
Inactives: OT Jaelyn Duncan, LB Luke Gifford, DT Teair Tart, DL Caleb Murphy, WR Treylon Burks and QB Will Levis
Lineup notes: WR Treylon Burks (knee) is out again.WR Kyle Philips was activated from injured reserve.
Colts
Inactives: LB Shaquille Leonard, OT Bernhard Raimann, TE Will Mallory, DE Kwity Paye and QB Sam Ehlinger
Lineup notes: RB Jonathan Taylor (ankle) was a full participant all week and had his questionable designation removed after being activated from the Reserve/Physically Unable to Perform list. DE Kwity Paye (concussion) and LB Shaquille Leonard (groin) are out. LT Bernhard Raimann (concussion) is out, but C Ryan Kelly cleared the protocol and will return.
New York Giants at Miami Dolphins (1:00 p.m. ET)
Kickoff Weather: 83 degrees, cloudy
Giants
Inactives:DT Jordon Riley, RB Saquon Barkley, S Gervarrius Owens, OG Shane Lemieux, OT Andrew Thomas, LB Micah McFadden and C John Michael Schmitz
Lineup notes: RB Saquon Barkley (ankle) still isn’t ready to return from a high-ankle sprain. New York will be without its starting left tackle and center, as well as a key reserve lineman.
Dolphins
Inactives: CB Kelvin Joseph, WR Chase Claypool, RB Salvon Ahmed, LB Jaelan Phillips, QB Skylar Thompson and DL Brandon Pili
Lineup notes: WR Braxton Berrios (knee) had full sessions Thursday and Friday and will play. LT Terron Armstead went on IR. WR Chase Claypool was acquired from Chicago but isn’t ready to play.
New Orleans Saints at New England Patriots (1:00 p.m. ET)
Kickoff Weather: 56 degrees, mostly clear, WSW 11 mph
Saints
Inactives: WR A.T. Perry, OG Andrus Peat, TE Juwan Johnson, DL Kyle Phillips, OT Landon Young, QB Jake Luton and CB Lonnie Johnson
Lineup notes: TE Juwan Johnson (calf) has been ruled out. QB Derek Carr (shoulder) is questionable after limited practices all week. OG Andrus Peat (concussion) won’t play.
Patriots
Inactives: OG Cole Strange, LB Matt Judon, WR Kayshon Boutte, OT Calvin Anderson, OT Tyrone Wheatley Jr. and QB Will Grier
Lineup notes: RB Rhamondre Stevenson (thigh) was questionable after limited work all week but is on the field. LB Matt Judon (biceps) and will not play but wasn’t put on the Reserve/Injured list, unlike CB Christian Gonzalez (shoulder) who was placed on IR. CB J.C. Jackson returns to the Pats after being reacquired via trade. CB Jonathan Jones (ankle) is active.
Baltimore Ravens at Pittsburgh Steelers (1:00 p.m. ET)
Kickoff Weather: 51 degrees, cloudy, W 17 mph
Ravens
Inactives: OT Morgan Moses, LB Odafe Oweh, CB Jalyn Armour-Davis, OT Malaesala Aumavae-Laulu, TE Charlie Kolar and QB Josh Johnson
Lineup notes: WR Odell Beckham Jr. (ankle) and WR Rashod Bateman (hamstring) will play. RB Justice Hill (foot, hamstring) graduated to a full practice Friday and is active. RB Kenyan Drake was elevated from the practice squad. RT Morgan Moses (shoulder) won’t go, but LT Ronnie Stanley (knee) is ready to play. LB Odafe Oweh (ankle) remains out, though CB Marlon Humphrey (foot) returns.
Steelers
Inactives: Dan Moore Jr., TE Pat Freiermuth, OG James Daniels, P Pressley Harvin III, DL DeMarvin Leal, QB Mason Rudolph and RB Godwin Igwebuike
Lineup notes: WR Diontae Johnson (hamstring) remains on IR with a hamstring injury. TE Pat Freiermuth (hamstring) is also out. RB Najee Harris (hamstring) was limited Friday but doesn’t carry an injury designation. QB Kenny Pickett (knee) practiced Thursday and Friday and is good to go. LB Alex Highsmith (groin) was questionable but is active. Pittsburgh is without its starting left tackle and right guard.
Philadelphia Eagles at Los Angeles Rams (4:05 p.m. ET)
Kickoff Weather: 69 degrees, clear (open-air dome)
Eagles
Inactives: TE Albert Okwuegbunam, DT Marlon Tuipulotu, S Sydney Brown, QB Tanner McKee, DL Fletcher Cox and RB Rashaad Penny
Lineup notes: DT Fletcher Cox (back) will not play.
Rams
Inactives: OG Joe Noteboom, DL Nick Hampton, WR Demarcus Robinson, DL Desjuan Johnson and OG Zachary Thomas
Lineup notes: WR Cooper Kupp (hamstring) was activated and will make his debut in Week 5. QB Matthew Stafford (hip) and RB Kyren Williams (hip) both had full sessions Friday and will play. Starting RG Joe Noteboom is inactive.
Cincinnati Bengals at Arizona Cardinals (4:05 p.m. ET)
Kickoff Weather: 94 degrees, cloudy (retractable-roof dome)
Bengals
Inactives: LB Akeem Davis-Gaither, OT D’Ante Smith, WR Tee Higgins, C Trey Hill, CB Chidobe Awuzie and DL Josh Tupou
Lineup notes: WR Tee Higgins (ribs) will miss this one after last week’s injury.
Cardinals
Inactives: S Qwuantrezz Knight, TE Elijah Higgins, DL Jonathan Ledbetter, OT Carter O’Donnell and RB Keaontay Ingram
Lineup notes: QB Kyler Murray (knee) is on the PUP as he recovers from a torn ACL.
New York Jets at Denver Broncos (4:25 p.m. ET)
Kickoff Weather: 70 degrees, clear
Jets
Inactives: WR Mecole Hardman, WR Jason Brownlee, CB D.J. Reed, CB Brandin Echols, RB Israel Abanikanda, LB Zaire Barnes and DE Carl Lawson
Lineup notes: Starting CB D.J. Reed (concussion) has been ruled out. WR Mecole Hardman and DE Carl Lawson are healthy scratches.
Broncos
Inactives: C Alex Forsyth, RB Javonte Williams, S JL Skinner, DL Thomas Incoom and DB Fabian Moreau
Lineup notes: RB Javonte Williams (quadriceps) is a somewhat surprising inactive after fully practicing Friday. Jerry Jeudy (knee) had full practices Thursday and Friday and will go.
Kansas City Chiefs at Minnesota Vikings (4:25 p.m. ET)
Kickoff Weather: Dome stadium
Chiefs
Inactives: LB Nick Bolton, DE B.J. Thompson, DE Matt Dickerson, OG Mike Caliendo and DL Keondre Coburn
Lineup notes: WR Kadarius Toney (toe) was a full participant all week and will play. LB Nick Bolton (ankle) isn’t ready just yet after being questionable.
Vikings
Inactives: LB Andre Carter II, QB Nick Mullens, TE Nick Muse, DT Khyiris Tonga, S Lewis Cine and OT Hakeem Adeniji
Lineup notes: C Garrett Bradbury (back) has no injury tag and will play.
Sunday Night Football
Dallas Cowboys at San Francisco 49ers (8:20 p.m. ET)
Kickoff Weather: 64 degrees, clear, NW 11 mph
Cowboys
Inactives: OT Asim Richards, QB Trey Lance, CB Eric Scott Jr., TE Peyton Hendershot, CB Israel Mukuamu, DL Villami Fehoko Jr. and WR Jalen Brooks
Lineup notes: WR CeeDee Lamb (knee) sat out Wednesday but was good to go the rest of the week and has no injury tag.
49ers
Inactives: DT Kalia Davis, LB Jalen Graham, TE Brayden Willis, OT Nick Zakelj, LB Randy Gregory and RB Elijah Mitchell
Lineup notes: RB Elijah Mitchell (knee) has been ruled out. WR Deebo Samuel (ribs, knee) avoids an injury designation, but he will be less than 100 percent. He was limited until a full session Friday. WR Brandon Aiyuk (shoulder) was limited early in the week but practiced fully Friday and will play. LB Randy Gregory was acquired from Denver but won’t be available this week.
Monday Night Football
Green Bay Packers at Las Vegas Raiders (8:15 p.m. ET)
Kickoff Weather: Dome stadium
Packers
Lineup notes: RB Aaron Jones (hamstring) is questionable, while WR Christian Watson (hamstring) avoided an injury tag; both were limited all week. OG Elgton Jenkins (knee) will return after being out since Week 2. CB Jaire Alexander (back) is questionable.
Raiders
Lineup notes: QB Jimmy Garoppolo (concussion) had a full practice Friday. WR Davante Adams (shoulder) advanced to just a limited status in Saturday’s practice and is questionable.